Mebeverine+chlordiazepoxide
About
Mebeverine+chlordiazepoxide belongs to a class of drugs called 'antispasmodics' primarily used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. Irritable bowel syndrome is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together.
Mebeverine+chlordiazepoxide is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort.
Take Mebeverine+chlordiazepoxide as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Most of these side effects of Mebeverine+chlordiazepoxide do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Mebeverine+chlordiazepoxide or any other medicines, please tell your doctor. Mebeverine+chlordiazepoxide is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised not to take Mebeverine+chlordiazepoxide if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Mebeverine+chlordiazepoxide may be excreted in breast milk. Therefore, avoid taking Mebeverine+chlordiazepoxide if you are breastfeeding. Mebeverine+chlordiazepoxide should be used with caution in the elderly as it may confuse them. Do not take Mebeverine+chlordiazepoxide for longer than the prescribed period as it may cause dependence. Please do not stop taking Mebeverine+chlordiazepoxide on your own as it might cause withdrawal symptoms. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), kidney or liver problems, inform your doctor before taking Mebeverine+chlordiazepoxide.
Uses of Mebeverine+chlordiazepoxide
Medicinal Benefits
Mebeverine+chlordiazepoxide is a combination of two drugs: Mebeverine and Chlordiazepoxide to treat symptoms of irritable bowel syndrome (IBS) and painful stomach cramps. Mebeverine belongs to the class of antispasmodics that works by relieving contractions associated with smooth muscles of the stomach and intestine. Chlordiazepoxide is a benzodiazepine that increases GABA (nerve-calming agent) activity in the brain and decreases nerve cells' abnormal active cells. Thereby relaxing muscles and reducing anxiety caused due to painful stomach cramps.
Directions for Use
Storage
Side Effects of Mebeverine+chlordiazepoxide
- Drowsiness
- Dizziness
- Light-headedness
- Slurred speech
- Tiredness
- Lack of coordination
- Difficulty in controlling movements
In-Depth Precautions and Warning
Drug Warnings
If you are known to be allergic to Mebeverine+chlordiazepoxide or any other medicines, please tell your doctor. Mebeverine+chlordiazepoxide is not recommended for children below 18 years of age, as the safety and effectiveness were not established. Avoid taking Mebeverine+chlordiazepoxide if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Mebeverine+chlordiazepoxide may be excreted in breast milk. Therefore, avoid taking Mebeverine+chlordiazepoxide if you are breastfeeding. Mebeverine+chlordiazepoxide should be used with caution in the elderly as it may cause confusion in them. Do not take Mebeverine+chlordiazepoxide for longer than the prescribed period as it may cause dependence. Please do not stop taking Mebeverine+chlordiazepoxide on your own as it might cause withdrawal symptoms. If you cannot digest or tolerate any sugars, please tell your doctor as Mebeverine+chlordiazepoxide contains sucrose and lactose. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Mebeverine+chlordiazepoxide.
Drug Interactions
Drug-Drug Interaction: Mebeverine+chlordiazepoxide may interact with pain killers (codeine, morphine), blood thinner (warfarin), benzodiazepine (diazepam), anticonvulsants (phenobarbitone, phenytoin), antibiotics (rifampicin), muscle relaxant (baclofen), antiparkinson drug (levodopa), antacids (cimetidine, omeprazole), heart-related medicines (digoxin), water pills (furosemide), bronchodilator (theophylline), anti-allergic drug (chlorphenamine).
Drug- Food Interaction: Avoid the intake of alcohol with Mebeverine+chlordiazepoxide as it may increase drowsiness.
Drug-Disease Interaction: If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and starts repeatedly during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Mebeverine+chlordiazepoxide.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption with Mebeverine+chlordiazepoxide as it may increase drowsiness. Please consult a doctor before consuming alcohol while using Mebeverine+chlordiazepoxide.
Pregnancy
unsafeMebeverine+chlordiazepoxide is not recommended for pregnant women as it may cause harm the foetus. However, please consult a doctor if you are pregnant.
Breast Feeding
unsafeMebeverine+chlordiazepoxide is not recommended for breastfeeding mothers as it is excreted in breast milk.
Driving
cautionMebeverine+chlordiazepoxide may cause drowsiness, dizziness or blurred vision in some people. So, drive only if you are alert and your vision is clear after taking Mebeverine+chlordiazepoxide.
Liver
cautionTake Mebeverine+chlordiazepoxide with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Mebeverine+chlordiazepoxide with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeMebeverine+chlordiazepoxide is not recommended for children below 18 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption.
- Maintain a healthy weight by exercising regularly.
- Avoid carbonated and caffeinated beverages.
- Practise relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
- Avoid deep-fried and spicy foods.
- Foods containing probiotics may help in providing relief from gas and bloating.
Special Advise
Please consult a doctor if the symptoms persist or worsen after using Mebeverine+chlordiazepoxide for more than 2 weeks.
Patients Concern
Disease/Condition Glossary
Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods, and beverages, irregular hormone levels, certain food, and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea.
FAQs
Mebeverine+chlordiazepoxide contains Mebeverine and Chlordiazepoxide. Mebeverine belongs to the class of antispasmodics that relaxes the muscles in the walls of the intestine and provides relief from painful muscle spasms. Thus, it reduces stomach pain caused by spasm, cramps, and gas formation, bloating, and discomfort. Chlordiazepoxide works by increasing GABA (nerve-calming agent) activity in the brain and decreasing the abnormal activity of nerve cells. Thereby, relaxes muscles, increases its calming action and reduces anxiety.
Mebeverine+chlordiazepoxide may cause dependence in patients especially when taken at high doses, for longer durations, or in patients with a history of drug abuse or alcoholism. Therefore, take Mebeverine+chlordiazepoxide only as prescribed.
Dizziness may be a side effect of Mebeverine+chlordiazepoxide. However, you are recommended to avoid driving if you feel dizzy after taking Mebeverine+chlordiazepoxide.
Yes, Mebeverine+chlordiazepoxide reduces stomach pain which is a symptom of irritable bowel syndrome. Mebeverine+chlordiazepoxide contains Mebeverine, an antispasmodic agent which reduces spasms, cramps and stomach pain. However, please consult a doctor before taking Mebeverine+chlordiazepoxide.
You are not recommended to take Mebeverine+chlordiazepoxide with diazepam as co-administration of these two medicines may increase the risk of adverse effects such as drowsiness, dizziness, difficulty in concentrating, or confusion. However, please consult your doctor before taking Mebeverine+chlordiazepoxide with other medicines.
Mebeverine+chlordiazepoxide should be used with caution in elderly patients. Mebeverine+chlordiazepoxide contains Chlordiazepoxide which may cause confusion in the elderly. However, please consult a doctor so that the dose may be adjusted appropriately.
