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Metformin+myo Inositol

About

Metformin+myo Inositol is a combination medicine used to treat polycystic ovary syndrome (PCOS). Polycystic ovary/ovarian syndrome is a hormonal disorder that causes enlarged ovaries with numerous small follicles. Symptoms include irregular periods, excess hair growth, acne, and obesity.

Metformin+myo Inositol is composed of two medicines, namely: Myo-inositol and Metformin. Myo-inositol reduces blood glucose levels and improves the ovulation process in women with PCOS. Metformin is an antidiabetic medicine that belongs to the class of biguanides. The majority of women with PCOS have higher insulin levels. Metformin is an insulin sensitizer that improves insulin sensitivity (body cells utilize insulin effectively to produce glucose) and thus increases the effects of insulin.

Your doctor will decide the dose and duration based on your medical condition. The common side effects of Metformin+myo Inositol include nausea, taste changes, diarrhoea, dizziness, stomach pain, and loss of appetite. Although not everyone experiences these side effects, if they occur, please seek medical attention. 

Before starting Metformin+myo Inositol, let your doctor know if you have any medical history of heart, kidney and liver diseases. Pregnant and breastfeeding women should consult their doctor before starting Metformin+myo Inositol. Metformin+myo Inositol may affect your blood sugar levels that can alter your driving ability, hence do not drive or operate machinery until you feel better. It is not recommended to consume alcohol along with Metformin+myo Inositol. Metformin+myo Inositol is not recommended in children younger than 10 years of age.

Uses of Metformin+myo Inositol

Polycystic ovarian syndrome (PCOS)

Medicinal Benefits

Metformin+myo Inositol is used to treat polycystic ovary/ovarian syndrome. It consists of Myo-inositol and Metformin. Myo-inositol is a vitamin-like substance. It reduces blood glucose levels and improves the ovulation process in women with PCOS. Metformin is an antidiabetic medicine that belongs to the class of biguanides. The majority of women with PCOS have higher insulin levels. Metformin is an insulin sensitizer that improves insulin sensitivity (body cells utilize insulin effectively to produce glucose) and thus increases the effects of insulin. This further decreases the inflammation in PCOS conditions and regularizes the ovulation process.

Directions for Use

Take Metformin+myo Inositol with or without food as prescribed by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Metformin+myo Inositol

  • Nausea
  • Changes in taste
  • Diarrhoea
  • Dizziness
  • Stomach pain
  • Loss of appetite 

In-Depth Precautions and Warning

Drug Warnings

Before starting Metformin+myo Inositol, let your doctor know if you have any medical history of mental disorders, thyroid diseases, hypervitaminosis D (high levels of vitamin D), hypercalcaemia (high levels of calcium in the blood), ketoacidosis (excess blood acids), tumours, and pernicious anaemia (decrease in red blood cells due to low vitamin B12). Metformin in Metformin+myo Inositol has an increased risk of lactic acidosis (a rare but serious metabolic complication of excess lactic acid in the blood caused by metformin accumulation). The risk of lactic acidosis is high in older people with kidney, liver and heart diseases. Pregnant and breastfeeding women should consult their doctor before starting Metformin+myo Inositol. Metformin+myo Inositol may affect your blood sugar levels that can alter your driving ability, hence so not drive or operate machinery until you feel better. Avoid consuming excessive alcohol as it can potentiate lactic acidosis.

Drug Interactions

Drug-Drug Interaction: Metformin+myo Inositol may interact with medicines used to treat high blood pressure (propranolol, metoprolol), pain killers, anti-depressants (fluoxetine, amitryptiline), cholesterol-lowering agents (cholestyramine), chemotherapy drugs (fluorouracil), anti-ulcers (sulfasalazine), anti-inflammatory drugs (ibuprofen, celecoxib), heart-related drugs (digoxin, digitalis), and corticosteroids (prednisone, hydrocortisone). 

Drug-Food Interaction: Limit alcohol intake since it affects blood sugar levels. Avoid fatty foods and include healthy carbohydrates in your diet.

Drug-Disease Interaction: Tell your doctor before taking Metformin+myo Inositol if you have liver, kidney or heart diseases, mental disorders, thyroid diseases, hypervitaminosis D, hypercalcaemia, ketoacidosis, tumours, and pernicious anaemia.

Drug-Drug Interactions Checker List:

  • PROPRANOLOL
  • METOPROLOL
  • FLUOXETINE
  • AMITRIPTYLINE
  • CHOLESTYRAMINE
  • FLUOROURACIL
  • SULFASALAZINE
  • IBUPROFEN
  • CELECOXIB
  • DIGOXIN
  • DIGITALIS
  • PREDNISONE
  • HYDROCORTISONE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is unsafe to consume alcohol since it may worsen the side effects.

    • Safety Warning

      Pregnancy

      caution

      There is limited data on how Metformin+myo Inositol affects pregnancy. Please consult your doctor before starting Metformin+myo Inositol if you are pregnant or planning to conceive.

    • Safety Warning

      Breast Feeding

      caution

      There is no sufficient data on how Metformin+myo Inositol affects breastfeeding. It is safe to seek medical advice before you start Metformin+myo Inositol if you are lactating.

    • Safety Warning

      Driving

      caution

      Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience dizziness or drowsiness.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases or hepatic impairment when prescribed Metformin+myo Inositol.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases when you are prescribed Metformin+myo Inositol.

    • Safety Warning

      Children

      caution

      Metformin+myo Inositol is not recommended in children younger than 10years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
    • Eat at regular intervals
    • Keep a check on your weight and exercise regularly.
    • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
    • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas.

    Special Advise

    • Timely ultrasound abdominal scanning is recommended to monitor your PCOS condition.

    Patients Concern

    Disease/Condition Glossary

    Polycystic ovary/ovarian syndrome: It is a hormonal disorder that causes enlarged ovaries with numerous small follicles. Women with PCOS produce higher levels of male hormones than usual. This hormonal imbalance can lead to irregularity in the menstrual cycle and problems in getting pregnant. Symptoms include irregular periods, excess hair growth, acne, and obesity. Treatment for PCOS includes birth control pills, cholesterol-lowering drugs, antidiabetic drugs, physical exercise, and weight loss.

    FAQs

    Metformin+myo Inositol contains Myo-inositol and Metformin. Metformin+myo Inositol reduces blood glucose levels and improves the ovulation process in women with PCOS. Decreased blood glucose levels are associated with decreased inflammation in PCOS, and further regularize the menstrual cycles. Thus, Metformin+myo Inositol effectively treats PCOS conditions.

    To minimize the occurrence of side effects, it is advised to take Metformin+myo Inositol at bedtime.

    Oral administration of Metformin+myo Inositol may decrease your blood sugar levels. Hence, it is advised to take Metformin+myo Inositol with a meal.

    Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

    Do not stop taking Metformin+myo Inositol on your own. To treat your condition effectually, continue taking Metformin+myo Inositol for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Metformin+myo Inositol.

    Available Medicines for

    Metformin+myo Inositol

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