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Methylcobalamin+folic Acid+pyridoxine+vitamin D3

About

Methylcobalamin+folic Acid+pyridoxine+vitamin D3 belongs to the multivitamins class, primarily used to treat nutritional deficiencies. It is used to treat and prevent vitamin B6 deficiency, folate deficiency, and vitamin B12 deficiency. Nutritional deficiency occurs when the body cannot absorb or get enough nutrients from food. It could lead to various health problems, including defective bone growth, skin disorders, digestive issues, and dementia (memory loss).

Methylcobalamin+folic Acid+pyridoxine+vitamin D3 is a combination of four essential vitamin supplements; Methylcobalamin, Folic acid, Pyridoxine, and Vitamin D3. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis. Folic acid helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. Pyridoxine is involved in protein, fat, and carbohydrate metabolism, the formation of red blood cells and neurotransmitters. Vitamin D3 (Cholecalciferol) helps maintain blood calcium and phosphorus levels and the mineralization of bone.

Use Methylcobalamin+folic Acid+pyridoxine+vitamin D3 as recommended. Sometimes, Methylcobalamin+folic Acid+pyridoxine+vitamin D3 may cause common side effects like vomiting, stomach upset, diarrhoea, drowsiness, flushing, and nausea. Most of these side effects do not require medical attention and gradually resolve over time. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use Methylcobalamin+folic Acid+pyridoxine+vitamin D3 if you are allergic to any of the components present in Methylcobalamin+folic Acid+pyridoxine+vitamin D3. Please consult your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food) so that the dosage form may be changed to intravenous administration for better absorption of vitamins. If you are a pregnant or breastfeeding mother, please consult your doctor before taking Methylcobalamin+folic Acid+pyridoxine+vitamin D3.

Uses of Methylcobalamin+folic Acid+pyridoxine+vitamin D3

Folate deficiency, Vitamin D deficiency, Vitamin B12 deficiency, and Vitamin B6 deficiency. 

Medicinal Benefits

Methylcobalamin+folic Acid+pyridoxine+vitamin D3 is used to treat nutritional deficiencies and contains Methylcobalamin, Folic acid, Pyridoxine, and Vitamin D3 (Cholecalciferol). Methylcobalamin regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Folic acid helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. Pyridoxine (vitamin B6) is involved in protein, fat, and carbohydrate metabolism, the formation of red blood cells and neurotransmitters. Vitamin D3 (Cholecalciferol) helps maintain blood calcium and phosphorus levels and mineralization of bone.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Methylcobalamin+folic Acid+pyridoxine+vitamin D3

  • Stomach upset
  • Diarrhoea
  • Drowsiness
  • Flushing
  • Nausea
  • Vomiting

In-Depth Precautions and Warning

Drug Warnings

Brief your medical history to doctor if you have any heart/kidney/liver diseases, kidney stones, Crohn's disease (inflammatory bowel disease), blood disorders like pernicious anaemia, Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food). Pregnant or breastfeeding women should consult their doctor before taking Methylcobalamin+folic Acid+pyridoxine+vitamin D3. Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Alcohol can also worsen the side effects like drowsiness and stomach upset. Hence, please avoid alcohol while using Methylcobalamin+folic Acid+pyridoxine+vitamin D3.

Drug Interactions

Drug-Drug Interactions: Methylcobalamin+folic Acid+pyridoxine+vitamin D3 may interact with anti-cancer drugs (altretamine, cisplatin, and arsenic trioxide), fits medicines (phenytoin, phenobarbital, primidone), antibiotic (chloramphenicol), medicines treating Parkinson's disease (levodopa), drugs used to treat tumours (Fluorouracil), antibiotics (trimethoprim), stomach related drugs (sulfasalazine), and cholesterol-lowering drugs (cholestyramine).

Drug-Food Interactions: Excessive alcohol consumption reduces absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Methylcobalamin+folic Acid+pyridoxine+vitamin D3.

Drug-Disease Interactions: Use Methylcobalamin+folic Acid+pyridoxine+vitamin D3 with medical advice if you have malabsorption syndrome (difficulty absorbing nutrition from food), hypercalcaemia (excess calcium levels), hypervitaminosis D (high vitamin D levels), malabsorption syndrome, Vitamin D toxicity, heart/kidney/liver/blood vessel diseases, kidney stones, Crohn's disease, Whipple's disease, achlorhydria, low levels of bile, phosphate imbalance, diabetes, and phenylketonuria.

Drug-Drug Interactions Checker List:

  • ALTRETAMINE
  • CISPLATIN
  • ARSENIC TRIOXIDE
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • CHLORAMPHENICOL
  • LEVODOPA
  • FLUOROURACIL
  • TRIMETHOPRIM
  • SULFASALAZINE
  • CHOLESTYRAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Methylcobalamin+folic Acid+pyridoxine+vitamin D3.

    • Safety Warning

      Pregnancy

      caution

      Methylcobalamin+folic Acid+pyridoxine+vitamin D3 should be used during pregnancy only when advised by your doctor. Let your doctor know if you are pregnant or planning to conceive before taking Methylcobalamin+folic Acid+pyridoxine+vitamin D3.

    • Safety Warning

      Breast Feeding

      caution

      Pyridoxine and Folic acid in Methylcobalamin+folic Acid+pyridoxine+vitamin D3 is excreted into the breast milk. Please consult your doctor before taking Methylcobalamin+folic Acid+pyridoxine+vitamin D3 if you are a breastfeeding mother.

    • Safety Warning

      Driving

      caution

      If you experience any dizziness while using Methylcobalamin+folic Acid+pyridoxine+vitamin D3, do not drive or operate machinery. Please consult your doctor if you experience any dizziness.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before taking Methylcobalamin+folic Acid+pyridoxine+vitamin D3. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

    • Safety Warning

      Kidney

      caution

      It is advised to seek doctor advice before starting Methylcobalamin+folic Acid+pyridoxine+vitamin D3 if you have kidney diseases like kidney stones or undergoing dialysis.

    • Safety Warning

      Children

      caution

      Please consult a doctor. The doctor will recommend the dosage of Methylcobalamin+folic Acid+pyridoxine+vitamin D3 based on the child's age and weight.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Try Vitamin B complex food sources like milk, cheese, eggs, liver, kidney, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
    • Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid.
    • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.
    • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
    • Include fruits like citrus, banana, and watermelon in your diet.
    • Avoid smoking and alcohol consumption.
    • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods. 

    Special Advise

    • Clinical monitoring of folic acid, vitamins D, B12, and B6 levels through blood examinations are recommended. 
    • Let your doctor and the laboratory staff know that you are using Methylcobalamin+folic Acid+pyridoxine+vitamin D3 since Pyridoxine may interfere with laboratory tests like urine tests for urobilinogen.

    Patients Concern

    Disease/Condition Glossary

    Vitamin D deficiency: When a person cannot get enough Vitamin D through food and exposure to sunlight, it leads to vitamin D deficiency. It often leads to thin, brittle, or misshapen bones.

    Vitamin B6 deficiency: When your body doesn't have adequate levels of a water-soluble vitamin called Pyridoxine or Vitamin B6, this disease is developed. Vitamin B6 deficiency symptoms include fatigue, skin rashes, cracked and sore lips, weak immune system, tiredness, low energy levels, tingling in hands and feet, and fits.

    Vitamin B12 deficiency: When your body doesn't have adequate mineral levels called Vitamin B12, it leads to Vitamin B12 deficiency. Symptoms include fatigue, breathlessness, numbness, poor balance, and memory trouble.

    Folate deficiency: Folate deficiency occurs when your body won't have enough folate in your diet. Symptoms include fatigue, grey hair, mouth sores, tongue swelling, and growth problems. Folate deficiency leads to anaemia.

    FAQs

    Methylcobalamin+folic Acid+pyridoxine+vitamin D3 is a dietary supplement and consists of Methylcobalamin (vitamin B12), Folic acid, Pyridoxine (vitamin B6) and Cholecalciferol (vitamin D3). When you lack these vitamins in your body, which cannot be recovered even with the food sources, Methylcobalamin+folic Acid+pyridoxine+vitamin D3 helps in normalising these deficient levels. Collectively, Methylcobalamin+folic Acid+pyridoxine+vitamin D3 treats nutritional deficiencies.

    Vitamin B6 deficiency occurs when your body lacks adequate Pyridoxine levels. You can overcome this deficiency by including food sources rich in Pyridoxine, like milk, eggs, beef, pork, chicken or turkey, fish, peanuts, soya beans, wheat germ, oats, and bananas. If your Vitamin B6 levels are still low, your doctor may advise supplements.

    Vitamin B12 deficiency is caused when you don't have enough Methylcobalamin or Mecobalmin levels in your body. You can include natural Vitamin B12 sources like eggs, beef, liver, chicken, trout, salmon, tuna fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese in your diet for treating the deficiency. If you still have low levels of B12, please consult your doctor for its supplements.

    Folate deficiency occurs when your body lacks adequate folic acid/folate levels. You can overcome this deficiency by including food sources rich in folic acid, like broccoli, brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid. If your folic acid levels are still low, your doctor may recommend supplements.

    It is important to tell your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food) since it may be hard to absorb vitamins through oral administration. Your doctor may recommend other dosage forms in such a case.

    Pyridoxine in Methylcobalamin+folic Acid+pyridoxine+vitamin D3 may interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Methylcobalamin+folic Acid+pyridoxine+vitamin D3 before undergoing any blood and urine examinations.

    Antacids may interfere with the absorption of Methylcobalamin+folic Acid+pyridoxine+vitamin D3. Hence it is advised to take Methylcobalamin+folic Acid+pyridoxine+vitamin D3 two hours before or four hours after taking antacids.

    If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

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