Metronidazole+norfloxacin

If you are allergic to norfloxacin, metronidazole or any other antibacterial or anti-amoebic agents, please inform your doctor to avoid unwanted side effects like swallowing or breathing problems, and swelling of your lips, face, throat or tongue. Taking Metronidazole+norfloxacin may increase the chances of developing tendinitis (swelling of a tissue that joins a bone to a muscle) or a tendon rupture. Dairy products should be avoided along with Metronidazole+norfloxacin. And also, exposure to sunlight should be avoided while taking Metronidazole+norfloxacin as it may cause increased phototoxicity or photosensitivity. Patients with an irregular heartbeat (QT prolongation) should tell their doctor before taking Metronidazole+norfloxacin. Metronidazole+norfloxacin should not be given to the pregnant mother (during the first trimester) and in nursing mothers as it passes into the breast milk. Please inform your doctor before taking Metronidazole+norfloxacin if you have a history of problems with your liver, blood, low white blood cell count (leukopenia), and nervous system (convulsions). Do not drink alcohol with Metronidazole+norfloxacin as it may cause flushing and drowsiness, which can alter your mental alertness.

Drug-Drug Interaction: This medicine may have an interaction with other antibiotics (sparfloxacin, azithromycin, sulfamethoxazole, trimethoprim, metronidazole, nitrofurantoin, erythromycin), calcium supplements (calcium/vitamin D), pain killers (ibuprofen or diclofenac), anti-asthma (theophylline), anti-diabetic (glibenclamide), anti-gout (probenecid), anti-cancer (busulfan, fluorouracil, mycophenolate), antidepressant (lithium), antiepileptic (phenobarbital, phenytoin) and blood thinner (warfarin).

Drug-Food Interaction: Metronidazole+norfloxacin interacts with dairy products (like milk or yogurt) or calcium-fortified juices alone, alcohol.

Drug-Disease Interaction: Inform your doctor if you have or have ever had a liver, kidney or heart problem or lung transplant, a joint or tendon disorder (rheumatoid arthritis), seizures (fits), low white blood cell count (leukopenia), epilepsy, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), seizures (fits), alcoholism, cancer, electrolyte imbalance (low potassium or magnesium level), colitis (inflammation of the intestine), porphyria (rare genetic blood disorder) and neuro-related diseases.

• Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola or chocolate. Metronidazole+norfloxacin may increase nervousness, sleeplessness and anxiety caused by caffeine.
• Probiotics should be taken after taking the full course of Metronidazole+norfloxacin to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria. 
• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Metronidazole+norfloxacin.
• Avoid alcoholic beverages with Metronidazole+norfloxacin as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Metronidazole+norfloxacin in fighting off infections.

• You should consult a doctor if you have symptoms associated with dehydration, like dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness.
• Metronidazole+norfloxacin may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Metronidazole+norfloxacin.