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Minoxidil+finasteride

About Minoxidil+finasteride

Minoxidil+finasteride belongs to a class of combination drug primarily used to treat alopecia (hair loss). Minoxidil+finasteride stimulates hair growth and slows down the process of balding. It is used to promote hair growth in androgenetic alopecia (male pattern hair loss). Alopecia is the thinning or loss of hair on the scalp or any part of the body. Androgenetic alopecia is the permanent hair loss from the scalp that causes baldness.

Minoxidil+finasteride consists of two medicines, namely Minoxidil (vasodilator) and Finasteride (5-alpha-reductase inhibitor). Minoxidil is a vasodilator that widens and the blood vessels and opens potassium channels. This vasodilation process helps provide oxygen, blood, and nutrients to the hair follicles, thereby preventing the hair cell death and promoting new hair growth. Finasteride is a 5-alpha-reductase inhibitor. It reduces dihydrotestosterone (male hormone) levels, thereby preventing thinning of hair follicles in people with androgenetic alopecia (male pattern hair loss). 

Use Minoxidil+finasteride as suggested by your doctor. Along with its needed effects, Minoxidil+finasteride may sometimes produce unwanted effects. Some common side effects of Minoxidil+finasteride include excessive hair growth, headache, skin irritation, itching, and dermatitis (itchy inflammation of the skin). These side effects usually do not require medical attention and gradually resolve during the treatment. If you experience any other symptoms you think may be due to Minoxidil+finasteride, please consult your doctor or pharmacist for further advice.

Do not use Minoxidil+finasteride for abrasion, sunburn, and psoriasis since Minoxidil can cause sodium and water retention, angina (chest pain), pericardial effusion (fluid around the heart), and other heart problems. Do not apply the topical form of Minoxidil+finasteride on shaved, inflamed, infected, irritated or painful scalp skin. Let your doctor know if you have a history of liver disease and urinary obstruction (blockage of urine flow) before using Minoxidil+finasteride. Pregnant and breastfeeding mothers should consult the doctor before starting Minoxidil+finasteride. 

Uses of Minoxidil+finasteride

Androgenetic alopecia (male/female pattern baldness).

Medicinal Benefits

Minoxidil+finasteride is a combination medicine of Minoxidil (vasodilator), and Finasteride (5-alpha-reductase inhibitor) used to treat alopecia (hair loss). Minoxidil is a vasodilator that stimulates hair growth and prevents baldness. When applied topically, Minoxidil promotes blood flow to the hair follicles, thereby providing sufficient nutrition and oxygen to the hair cell. This process of supplying oxygen and nutrients to the hair cell prevents its death and stimulates hair growth. Finasteride is a 5-alpha-reductase inhibitor which reduces dihydrotestosterone (male hormone) levels, thereby preventing thinning of hair follicles in people with androgenetic alopecia (male pattern hair loss). 

Directions for Use

Solution/Spray: Generally, the solution form comes with a spray pump applicator and an extended spray-tip applicator. Aim the pump of the spray towards the bald areas of the scalp and pump it once. Then, spread the solution with your fingertips. A total of six sprays would deliver one ml of the medication. Avoid breathing in the spray mist and wash your hands thoroughly after application. Use the spray pump applicator to apply the solution to large areas of skin and spray-tip applicator on the small areas. Foam: The foam comes in a spray nozzle bottle. Press the nozzle to put the foam on your fingers. Now, use your fingers to spread the foam on the bald areas and massage gently into the scalp. Wash your hands thoroughly after application. Gel/Lotion: Take the advised amount of gel/lotion with clean and dry hands on the scalp's affected areas. Gently massage the medicine into the skin with your fingers. Wash your hands after applying. Shampoo: Wet your hair with a sufficient quantity of water. Apply the shampoo on the scalp depending on the length of the hair. Massage to lather and leave it on the scalp and hair for a few minutes. Then, thoroughly rinse with water. Avoid contact of shampoo with eyes. In case of accidental contact with eyes, rinse with water thoroughly. Do not blow-dry your scalp after using this product. Do not apply the product on shaved, inflamed, infected, irritated or painful scalp skin. If the medicine gets into your eyes, nose or mouth, broken or irritated skin, rinse with cold water.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Minoxidil+finasteride

  • Excessive hair growth
  • Headache
  • Skin irritation
  • Itching
  • Dermatitis

Drug Warnings

Tell your doctor before using Minoxidil+finasteride if you have a history of liver disease and urinary obstruction (blockage of urine flow). Do not use the topical Minoxidil+finasteride, if you have high blood pressure, cardiovascular disease or cardiac arrhythmia (abnormal heart rhythms), sunburn, and psoriasis without a doctor's advice. Let your doctor know if your allergic to Minoxidil+finasteride or any of its components, such as propylene glycol and ethanol (alcohol). Finasteride in Minoxidil+finasteride may be unsafe to use during pregnancy since it may have harmful effects on the foetus. If you are pregnant, planning for pregnancy or breastfeeding mother, Please consult a doctor before using Minoxidil+finasteride. Avoid smoking or going near naked flames when you have applied the Minoxidil+finasteride since it can catch fire and burn easily. 

Drug Interactions

Drug-Drug Interaction: Minoxidil+finasteride may interact with drugs treating erectile dysfunction (sildenafil).

Drug-Food Interaction: No interactions were found.

Drug-Disease Interaction: Minoxidil+finasteride is contraindicated in liver disease, urinary obstruction, high blood pressure, cardiovascular disease or cardiac arrhythmia, sunburn, and psoriasis.

Drug-Drug Interactions Checker List:

  • SILDENAFIL
  • Safety Advice

    • Safety Warning

      Alcohol

      safe if prescribed

      No interaction found/ established. Please consult your doctor before using Minoxidil+finasteride.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are planning to become pregnant or already pregnant before starting Minoxidil+finasteride.

    • Safety Warning

      Breast Feeding

      caution

      It is not known if Minoxidil+finasteride passes into the breast milk and harms a baby during breastfeeding. Please consult the doctor before using Minoxidil+finasteride if you are a nursing mother.

    • Safety Warning

      Driving

      safe if prescribed

      No interaction found/established.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Minoxidil+finasteride.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Minoxidil+finasteride. However, it should be cautiously used in patients with kidney problems and urinary obstruction.

    • Safety Warning

      Children

      unsafe

      Safety and efficacy have not been established in patients younger than 18 years.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • It is advised to maintain a healthy diet with well-balanced meals.
    • Avoid overusing styling tools like blow dryers, curling rods, and chemical dying, which can cause loss of natural hair oils and cause hair fall.
    • Regular oiling helps in the blood circulation of the scalp and nourishes the roots.
    • Washing your hair twice a week with a good shampoo and conditioner can also improve your hair fall.
    • Practise yoga and meditation to control your stress, which is the greatest enemy of hair fall.
    • Get regular medical examinations to check your hormonal profile and nutritional deficiencies that cause hair fall. 

    Special Advise

    • It is advised to monitor your hormonal and vitamin D profiles, which can affect your hair loss.
    • Avoid contact of topical Minoxidil+finasteride with nose, mouth, eyes or broken, irritated skin as it may irritate. In case Minoxidil+finasteride comes in contact with these areas accidentally, rinse with water thoroughly.

    Patients Concern

    Disease/Condition Glossary

    Androgenetic alopecia: It is also known as male or female pattern baldness. In male-pattern baldness, hair loss occurs on the top and front of the head. On the other hand, in female pattern baldness, thinning occurs on the top and crown of the head. This condition is usually genetic in nature or mediated by the excessive secretion of the androgen dihydrotestosterone in both genders. 

    FAQs

    Minoxidil+finasteride contains Minoxidil and Finasteride. Minoxidil is a vasodilator that widens and relaxes the constricted blood vessels promoting the blood flow to the hair cells. This process helps nourish the hair cells with the supply of oxygen and nutrients and stimulate hair growth. Finasteride is a 5-alpha-reductase and inhibits miniaturization/thinning of hair follicles in patients with androgenetic alopecia (male/female pattern hair loss).

    Hair growth is a slow process, and it usually takes 4 months to see the best results of Minoxidil+finasteride. It is advisable to apply at least 2 times a day for better result.

    Minoxidil+finasteride is for topical (scalp area) use only and not other parts. Do not put bandage or dressing on the affected area while treating with Minoxidil+finasteride. If the medicine gets into your eyes, nose or mouth, rinse with cold water. Do not blow-dry your scalp after using Minoxidil+finasteride. Do not apply the topical form of Minoxidil+finasteride on shaved, inflamed, infected, irritated or painful scalp skin.

    Please consult your doctor before using Minoxidil+finasteride if you have liver disease and urinary obstruction (blockage of urine flow). Do not apply the topical form of Minoxidil+finasteride on shaved, inflamed, infected, irritated or painful scalp skin. Let your doctor know if your allergic to Minoxidil+finasteride or any of its components, such as propylene glycol and ethanol (alcohol). Do not use a topical form of Minoxidil+finasteride, if you have high blood pressure, cardiovascular disease or cardiac arrhythmia (abnormal heart rhythms), sunburn, and psoriasis.

    Minoxidil+finasteride is for scalp use and do not apply it on your face since it causes undesirable facial hair growth. If Minoxidil+finasteride gets in contact with any other body areas, rinse with water thoroughly.

    Do not use Minoxidil+finasteride for beard growth. Minoxidil+finasteride is recommended for only hair loss on the scalp.

    According to the FDA's guidelines, women can use only 2% of Minoxidil for hair loss. Hence, it is better to avoid Minoxidil+finasteride in women unless advised by the doctor.

    Do not freeze Minoxidil+finasteride. Please keep it away from direct sunlight. Keep Minoxidil+finasteride foam canister away from open flame or high heat, since it may explode. Do not puncture or burn an empty canister.

    Available Medicines for

    Minoxidil+finasteride

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