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Monobenzone

About

Monobenzone contains a topical depigmenting agent indicated for the final depigmentation in extensive vitiligo. It is used to lighten skin in people with vitiligo permanently. Vitiligo is a disease that causes loss of skin colour in blotches.

Monobenzone contains Monobenzone that works by increasing the elimination of melanin (pigment molecules) from skin cells. It depigments darker areas around the areas of vitiligo and helps even out the colouring and appearance of the skin.

In some cases, Monobenzone may cause mild skin irritation, dryness or flaking of treated skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, consult a doctor.

Do not use Monobenzone if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Monobenzone is not recommended for children. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Monobenzone

Vitiligo

Medicinal Benefits

Monobenzone contains Monobenzone, a topical depigmenting agent indicated for the final depigmentation in extensive vitiligo. It is used to lighten skin in people with vitiligo permanently in patients with disseminated (greater than 50 per cent of body surface area) idiopathic vitiligo. Monobenzone works by increasing the elimination of melanin (pigment molecules) from skin cells. It depigments darker areas around the areas of vitiligo and helps even out the colouring and appearance of the skin.

Directions for Use

Use Monobenzone exactly as advised by the doctor. Apply as a thin layer and rub into the pigmented area.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Monobenzone

  • Mild skin irritation
  • Dryness or flaking of treated skin

In-Depth Precautions and Warning

Drug Warnings

Do not use Monobenzone if you are allergic to any of its components. Monobenzone is not recommended in Berloque dermatitis (hyperpigmentation caused by photosensitisation following the use of certain perfumes), freckling, melasma of pregnancy, malignant melanoma, hyperpigmentation resulting from inflammation of the skin, or pigmentation resulting from pigments other than melanin (artificial pigments, bile, silver). Consult your doctor if you are pregnant or breastfeeding. This medicine should not be used in children below 12 years. Let your doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: No interactions found/established.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    consult your doctor

    It is not known whether alcohol interacts with Monobenzone. Please consult your doctor.

  • Safety Warning

    Pregnancy

    caution

    Monobenzone belongs to pregnancy category C. Monobenzone should be used during pregnancy only if clearly needed.

  • Safety Warning

    Breast Feeding

    caution

    It is not known if Monobenzone passes into breast milk. Caution should be exercised while administering Monobenzone to a nursing woman.

  • Safety Warning

    Driving

    not applicable

    -

  • Safety Warning

    Liver

    consult your doctor

    Limited data is available. Please consult your doctor if you have concerns regarding the usage of Monobenzone in patients with liver impairment.

  • Safety Warning

    Kidney

    consult your doctor

    Limited data is available. Please consult your doctor if you have concerns regarding the usage of Monobenzone in patients with kidney impairment.

  • Safety Warning

    Children

    unsafe

    Monobenzone is not recommended for children below 12 years as the safety and effectiveness have not been established.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and drink lots of water.
  • Include foods rich in antioxidants and omega-3 fatty acids like whole grains, walnuts, seaweed, and mackerel.
  • Avoid processed meat, refined grains, sugar-sweetened beverages, and fried foods.
  • Reduce stress by doing yoga or meditation.
  • Nutrient-rich foods like vegetables, fruits, whole grains, seeds, nuts, legumes, and lean protein may help promote good health and limit inflammation.

Special Advise

  • Always remember to wear sunscreen as the skin treated with Monobenzone may be sensitive to sunlight for the rest of your life. 

Patients Concern

Disease/Condition Glossary

Vitiligo: Vitiligo is a disease that causes loss of skin colour in blotches. It occurs when the pigment-producing cells called melanin die or stop functioning. Vitiligo is generally considered to be an autoimmune disorder (the immune system attacks the body's own tissues and organs). It can affect any part of the skin; however, it mostly occurs on the face, neck, creases, and hands.

FAQs

Monobenzone works by increasing the elimination of melanin (pigment molecules) from skin cells.

Skin treated with Monobenzone may become sensitive to sunlight and make you sunburn more easily. Therefore, avoid exposure to tanning beds and sunlight. Also, use sunscreen and wear protective clothing when outdoors.

Monobenzone is a potent depigmentation agent and not a cosmetic bleach. It should not be used in any other conditions except for disseminated vitiligo.

Monobenzone may also change the colour of untreated skin. Consult your doctor if you have concerns about depigmentation of other skin areas unaffected by vitiligo.

Available Medicines for

Monobenzone

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