MOSAPRIDE
About
MOSAPRIDE contains a class of medicines known as 'gastrointestinal agents,' primarily used to treat gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus). Gastroesophageal reflux disease (GERD) is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.
MOSAPRIDE contains Mosapride, primarily used to treat GERD (gastro-oesophageal reflux disease). It works by increasing the release of certain chemicals (acetylcholine), which helps improve food movement inside the intestine. Thus, gastric emptying of both liquid and solid from the intestine is increased.
Take MOSAPRIDE as prescribed. Depending on your medical condition, you are advised to take MOSAPRIDE for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects such as dizziness, headache, nausea, diarrhoea, dry mouth, abdominal pain, headache, insomnia (difficulty sleeping), unusual tiredness and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor before taking MOSAPRIDE if you have a stomach or intestine tumour, liver or kidney disease, or intestinal bleeding. Do not take MOSAPRIDE if you are pregnant or breastfeeding. MOSAPRIDE may cause dizziness and sleepiness, so drive only if you are alert. MOSAPRIDE should not be given to children as safety has not been established. Avoid consuming alcohol and grapefruit juice along with MOSAPRIDE as it could lead to increased drowsiness and can elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of MOSAPRIDE
Medicinal Benefits
MOSAPRIDE contains a class of medicines known as 'gastrointestinal agents,' containing Mosapride, primarily used to treat gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus). It is basically a gastroprokinetic agent that increases gastrointestinal motility. It works by increasing the release of certain chemicals (acetylcholine), which helps improve food movement inside the intestine. Thus, gastric emptying of both liquid and solid from the intestine is increased.
Directions for Use
Storage
Side Effects of MOSAPRIDE
- Dizziness
- Headache
- Diarrhoea
- Nausea
- Dry mouth
- Abdominal pain and cramps
- Sleeplessness
- Loss of appetite
- Unusual tiredness and weakness
In-Depth Precautions and Warning
Drug Warnings
Do not take MOSAPRIDE if you are allergic to any of its contents. Inform your doctor before taking MOSAPRIDE if you have a stomach, intestine tumour, or liver disease. Do not take MOSAPRIDE if you are pregnant or breastfeeding, as its safety and efficacy are not yet established. MOSAPRIDE may cause dizziness and sleepiness, so drive only if you are alert. MOSAPRIDE should not be given to children as safety has not been established. Avoid consuming alcohol and grapefruit juice along with MOSAPRIDE as it could lead to increased drowsiness and can elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side effects. MOSAPRIDE should be taken with caution in elderly patients as they are more prone to adverse effects of the MOSAPRIDE so dose adjustment might be required. If you have gastrointestinal bleeding, please do not take MOSAPRIDE as it might increase your bleeding and lead to bloody or coffee-coloured stools.
Drug Interactions
Drug-Drug Interactions: MOSAPRIDE may have interaction with antibiotics (erythromycin), anti-fungal (ketoconazole), anti-malarial (quinine), heart medicines (amiodarone, sotalol), anti-psychotic (haloperidol), antihistamine (terfenadine).
Drug-Food Interactions: Avoid smoking, grapefruit juice and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Drug-Disease Interactions: MOSAPRIDE may have interactions with liver, kidney or heart disorders, respiratory disorders (hypercapnia (too much carbon-di-oxide in the bloodstream) and hypoxemia (low level of oxygen in bloodstream)), gastrointestinal bleeding, any obstruction in the intestine, stomach or intestine tumour.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking MOSAPRIDE. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Pregnancy
cautionThe safety and efficacy are not known in pregnant women. So, you should take it only if prescribed by a doctor.
Breast Feeding
cautionIt is unknown whether the MOSAPRIDE passes through the breast milk. So, you should take it only if prescribed by a doctor.
Driving
unsafeMOSAPRIDE may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please discuss with your doctor if you have a liver impairment or any concerns.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please discuss with your doctor if you have a liver impairment or any concerns.
Children
cautionMOSAPRIDE should not be given to children as safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
- Maintain a healthy weight by regular exercising.
- Avoid lying down after eating to prevent acid reflux.
- Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
- Practice relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
- Avoid sitting continuously, as it may trigger acidity. Take a break of 5 minutes every hour by brisk walking or stretching.
Special Advise
- Close monitoring of heart functions is required if you have any heart disease and are taking MOSAPRIDE.
- Avoid consumption of grapefruit juice and alcohol while taking MOSAPRIDE.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like acidity, GERD, heartburn, peptic ulcer, and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.
FAQs
MOSAPRIDE contains a class of medicines known as 'gastrointestinal agents,' containing Mosapride, that works by increasing the release of certain chemicals (acetylcholine), which helps to improve the movement of food inside the intestine. Thus, there is increased gastric emptying of both liquid and solid from the intestine.
Avoid or limit the consumption of alcohol while taking MOSAPRIDE as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
Diarrhea might be a side-effect of MOSAPRIDE. Drink lots of fluids and eat food rich in fiber if you experience diarrhea. If you find blood in stools (tarry stools) or if you experience excess diarrhea consult your doctor. Prolonged intake of MOSAPRIDE is linked with a greater risk of Clostridium difficile-associated diarrhea, so if you develop diarrhea that does not improve, immediately consult a doctor.
Dry mouth could be a side-effect of MOSAPRIDE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Talk to your doctor if you do not feel better even after taking MOSAPRIDE for 14 days. Do not take MOSAPRIDE for longer durations unless prescribed by the doctor. If MOSAPRIDE is prescribed for longer durations, a regular check-up is advised.
