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Moxifloxacin+dexamethasone

About

Moxifloxacin+dexamethasone belongs to the class of ‘antibiotics’ used to treat inflammation associated with bacterial eye infections. It treats eye infections like conjunctivitis (infected conjunctiva) and other inflammatory conditions after eye surgery. 

Moxifloxacin+dexamethasone is a combination of two medicines: Moxifloxacin (antibiotic) and Dexamethasone (steroid). Moxifloxacin is an antibiotic that stops bacteria from making a copy of their genetic material (DNA), thereby killing and stopping the growth of bacterial infection. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection such as redness and irritation by inhibiting the natural substance like prostaglandins that cause inflammation. Thus together Moxifloxacin+dexamethasone prevents spread of redness, allergies, inflammation and bacterial infection in the eyes. 

You should use this medicine as prescribed by your doctor. The common side-effects of Moxifloxacin+dexamethasone are application site burning/stinging sensation or redness and temporary blurred vision. While using eye drops, if swelling or sensitivity to light occurs, wash your eyes thoroughly with cold water after 15 minutes. If the condition does not improve, consult your doctor immediately. 

Do not use Moxifloxacin+dexamethasone if you are allergic to Moxifloxacin, Dexamethasone, or any contents of it. Before taking Moxifloxacin+dexamethasone, inform your doctor if you have fungal infections, viral infections such as viral infection of the conjunctiva or cornea of an eye, herpes simplex or varicella, or parasitic infections such as amoebiasis. Do not use Moxifloxacin+dexamethasone if you have tuberculosis, damaged cornea, ulceration, lesions with incomplete formation of the covering tissue, and increased pressure inside the eye.

Uses of Moxifloxacin+dexamethasone

Bacterial eye infections.

Medicinal Benefits

Moxifloxacin+dexamethasone is a combination of two medicines: Moxifloxacin and Dexamethasone. Moxifloxacin is a fluoroquinolone antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid medicine that has anti-inflammatory properties and acts by inhibiting the chemicals such as prostaglandins that cause inflammation. It also reduces symptoms associated with infection such as redness and irritation.

Directions for Use

Eye drops/Ophthalmic solution: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Moxifloxacin+dexamethasone

  • Stinging or burning sensation
  • Redness 
  • Blurred vision
  • Swelling
  • Watery eyes

In-Depth Precautions and Warning

Drug Warnings

Before taking Moxifloxacin+dexamethasone, inform your doctor if you have vision problems, severe pain in the eye, glaucoma (raised pressure in the eye), eye injury or eye surgery, or using any other eye drops or eye ointment. Inform your doctor immediately if you notice swelling or weight gain around the trunk or in the face, as it may be a sign of Cushing’s syndrome (high levels of cortisol in the body). Do not use eye drops for longer than recommended by your doctor as it may suppress adrenal gland function and may increase the risk of cataracts (clouding of the eye). Moxifloxacin+dexamethasone should be not be used in the skin conditions like herpes simplex virus infection, or other viral eye infections. 

Drug Interactions

Drug-Drug Interaction: Moxifloxacin+dexamethasone may interact with other antibiotics, antiviral or anti-HIV (ritonavir, cobicistat).

Drug-Food Interaction: No interactions were found.

Drug-Disease Interaction: Moxifloxacin+dexamethasone should not be used in patients with fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis, tuberculosis, damaged cornea, ulceration, and glaucoma (increased pressure inside the eye).

Drug-Drug Interactions Checker List:

  • RITONAVIR
  • COBICISTAT
  • Safety Advice

    • Safety Warning

      Alcohol

      safe if prescribed

      It is advisable to avoid alcohol intake while using Moxifloxacin+dexamethasone as it may affect your ability to fight infections.

    • Safety Warning

      Pregnancy

      unsafe

      Moxifloxacin+dexamethasone is a category C medicine. Moxifloxacin+dexamethasone may cause some side effects to the unborn baby or fetus, so it should not be used in pregnant women.

    • Safety Warning

      Breast Feeding

      caution

      Moxifloxacin+dexamethasone should be used with caution in breastfeeding mothers.

    • Safety Warning

      Driving

      caution

      Moxifloxacin+dexamethasone may cause vision problems. However, it will be mild and temporary in nature. So, it is advisable to avoid driving until your vision clears.

    • Safety Warning

      Liver

      safe if prescribed

      Moxifloxacin+dexamethasone can be used for treating eye infections in patients with liver diseases.

    • Safety Warning

      Kidney

      safe if prescribed

      Moxifloxacin+dexamethasone can be used for treating eye infections in patients with kidney diseases.

    • Safety Warning

      Children

      caution

      Moxifloxacin+dexamethasone should be used with caution in children. It is not recommended for use in newborns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Sleep for at least six to eight hours to rejuvenate your eyes naturally.
    • Wash your eyes with clean water at least two to three times a day. Do not wash your eyes if you have undergone any eye surgery for at least 2 weeks. 
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Avoid alcoholic beverages as it can make you dehydrated and affect your sleep. This effect can also affect your body’s ability to fight off infections. 

    Patients Concern

    Disease/Condition Glossary

    Bacterial eye infections: These are the common eye problems seen in a primary care setting. The common bacterial eye infections are conjunctivitis, stye, or keratitis. Conjunctivitis (pink eye) is the inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that is spread by secretions of the eye. Symptoms include redness, itchy, and discharge or crusting around the eye. A stye, a bump on the eyelid, is also a common eye condition. Keratitis, inflammation of the cornea, occurs due to frequent contact lenses, injury, diabetes, or surgery.  

    FAQs

    Moxifloxacin+dexamethasone is a combination of two medicines: Moxifloxacin and Dexamethasone. Moxifloxacin is a bactericidal antibiotic (kills bacteria) by stopping making a copy of their genetic material (DNA), thereby preventing bacterial infection growth. Dexamethasone is a steroid that helps prevent allergic symptoms or inflammatory conditions caused due to the bacterial infection or any eye surgery. Thus, together Moxifloxacin+dexamethasone helps in preventing the bacterial eye infections.

    Moxifloxacin+dexamethasone usually improves symptoms within 3 to 5 days. However, use medicine for a duration recommended by your doctor. Please do not use for more than the recommended duration as it contains dexamethasone, which is a steroid and can cause unwanted side-effects.

    Inform your doctor before any medications while using Moxifloxacin+dexamethasone. If your doctor advises you to take other eye drops along with Moxifloxacin+dexamethasone, maintain an interval of at least 5 minutes between two eye drops.

    Do not wear contact lenses while using Moxifloxacin+dexamethasone. Also, avoid prolonged use, as it may cause cataracts (clouding of the eye).

    Available Medicines for

    Moxifloxacin+dexamethasone

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