Sucralfate+mupirocin
About
Mupirocin+sucralfate belongs to the class of ' Protectants and Antimicrobial agent' primarily used to treat burns, wound infections and bacterial skin infections such as impetigo. A burn damages the skin or deeper tissues caused by hot liquids, fire, electricity and chemicals. The degree of severity of burns is based on the size and depth of the burn. A skin infection can occur when the skin is broken, cut, or wounded. Impetigo is a highly communicable bacterial skin infection that causes red sores on the face.
Mupirocin+sucralfate is a combination of two medicines, namely; Sucralfate and Mupirocin. Sucralfate is a protectant with anti-inflammatory properties which forms a coating over the affected skin surface. This creates a cytoprotective effect and forms a viscous, adhesive barrier on the surface of the infected skin. It stimulates the synthesis and release of prostaglandins and the epidermal growth factor which stimulates healing. On the other hand, Mupirocin works by inhibiting the production of essential proteins that are necessary for bacteria to grow, multiply and increase in numbers, thereby preventing the growth of bacteria. Thereby, Mupirocin+sucralfate kills bacteria and clears the infection, and reduces inflammation symptoms (burning sensation, irritation swelling, and pain).
Mupirocin+sucralfate is for external use only. Apply Mupirocin+sucralfate as prescribed by your doctor. You are advised to apply Mupirocin+sucralfate for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, you may experience a burning sensation at the application site. The side effects of Mupirocin+sucralfate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Brief your medical history to the doctor, if you are allergic to Mupirocin+sucralfate or its components. Please consult your doctor if you are pregnant or planning to conceive before using Mupirocin+sucralfate. It is not known whether Mupirocin+sucralfate passes into breast milk or not. It is advised to seek medical advice before using Mupirocin+sucralfate if you are a breastfeeding mother. Do not apply Mupirocin+sucralfate in large amounts or use it for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Mupirocin+sucralfate may not interact with alcohol. Mupirocin+sucralfate may not affect your ability to drive.
Uses of Sucralfate+mupirocin
Medicinal Benefits
Mupirocin+sucralfate is a combination of two medicines, namely; 'Sucralfate and Mupirocin' used to treat burns and wound infections. It is also used to treat impetigo (skin infection). Besides this, it is also used as an antiseptic in minor cuts and abrasions. Sucralfate is a protectant with anti-inflammatory properties which forms a coating over the affected skin surface. This creates a physical barrier that protects the skin from further injury and stimulates the synthesis and release of prostaglandins and the epidermal growth factor which stimulates healing. Mupirocin is a topical broad-spectrum antimicrobial agent and has bactericidal activity against gram-positive and gram-negative bacteria and yeasts, which contaminate skin and mucosa. It kills the bacteria that cause skin infections by preventing the synthesis of essential proteins and RNA synthesis necessary for the survival of bacteria. Collectively, Mupirocin+sucralfate prevents the skin infection from spreading, and reduces inflammation symptoms (burning sensation, irritation swelling, and pain). This promotes the healing of burns and wounds.
Directions for Use
Storage
Side Effects of Sucralfate+mupirocin
- Burning at the site of application
- Rash
- Allergic reaction
- Itching
- Tingling Sensation
In-Depth Precautions and Warning
Drug Warnings
Mupirocin+sucralfate is for external use only. Do not swallow the medicine. Do not use Mupirocin+sucralfate, if you are allergic to Mupirocin+sucralfate or other medicines. Do not take Mupirocin+sucralfate for longer durations unless prescribed by your doctor as a second infection may happen. Please consult your doctor if you are pregnant or planning to conceive before using Mupirocin+sucralfate. It is not known whether Mupirocin+sucralfate passes into breast milk or not. It is advised to seek medical advice before using Mupirocin+sucralfate if you are a breastfeeding mother. Avoid contact of Mupirocin+sucralfate with nose, ears, mouth or eyes. In case Mupirocin+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. Wear sterile disposable gloves if you apply Mupirocin+sucralfate for others and keep the treated area clean to prevent further infection. Do not cover the affected areas with bandages or dressing after applying Mupirocin+sucralfate if the doctor did not advise. Do not apply Mupirocin+sucralfate in large amounts or use it for a long time than prescribed as it does not give quick or better results but increases the risk of side effects.
Drug Interactions
Drug-Drug Interactions: Mupirocin+sucralfate may interact with an antibiotic (ciprofloxacin, norfloxacin, lomefloxacin, ofloxacin), medicines used to treat heart diseases (digoxin, quinidine), antiulcer (cimetidine), antifungal (ketoconazole), used to treat an underactive thyroid gland (levothyroxine), anti-seizure (phenytoin).
Drug-Food Interactions: No interaction found/established.
Drug-Disease Interactions: Before taking Mupirocin+sucralfate, let your doctor know if have any allergic reactions to Mupirocin+sucralfate, tuberculosis of the skin and varicose ulcers, skin lesions caused by infections with viruses (herpes simplex, vaccinia or varicella).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionInteraction of Mupirocin+sucralfate with alcohol is unknown. Please consult a doctor before consuming alcohol while using Mupirocin+sucralfate.
Pregnancy
cautionThe safety of Mupirocin+sucralfate in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionIt is unknown whether Mupirocin+sucralfate is excreted in breast milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.
Driving
safe if prescribedMupirocin+sucralfate usually does not affect your ability to drive or operate machinery.
Liver
safe if prescribedMupirocin+sucralfate is probably safe when used in patients with liver diseases.
Kidney
safe if prescribedMupirocin+sucralfate is probably safe when used in patients with kidney diseases.
Children
cautionMupirocin+sucralfate should not be used in children unless prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Cool down the burn immediately by placing it under running water or apply a cool and wet compress until the pain decreases.
- Remove any accessories like jewellery, belts and tight clothing you are wearing since burns can swell quickly.
- Consider getting a tetanus shot.
- Avoid harsh products on your skin.
- Do not scratch or pick your skin to avoid getting the affected area infected.
- Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
- Do not walk barefoot at places like gym showers to prevent bacterial infections.
Special Advise
Please consult a dermatologist if your skin condition persists for more than 3 to 4 weeks.
Patients Concern
Disease/Condition Glossary
Burns: A burn damages the skin or deeper tissues that can be caused by hot liquids, fire, electricity and chemicals. The degree of severity of burns is based on the size and depth of the burn.
Skin infection: A skin infection can occur when the skin is broken, cut, or wounded. This skin infection allows pathogenic microorganisms to enter and invade the tissues surrounding the wound. Infection of the wound can trigger the body's immune response, causing inflammation and tissue damage and eventually slows down the healing process.
Impetigo: A highly contagious skin infection caused by bacteria that mainly affects infants and children but adults may also have the infection in rare cases. It usually appears as red sores on the face, especially around a child's nose and mouth, and on hands and feet. After burst, the sores developed honey-colored crusts.
FAQs
Mupirocin+sucralfate contains Sucralfate and Mupirocin. Sucralfate is a protectant that works by forming a protective layer over the affected area of skin and prevents pain, irritation, or burning sensation in the skin. Thereby, promotes the healing of burns and wound skin and the formation of new healthy skin. Mupirocin is an antibiotic that works by killing infectious bacteria by preventing the synthesis of essential proteins necessary for the survival of bacteria. Together, Mupirocin+sucralfate prevents the skin infection from spreading and protects the skin from further injury, allowing it to heal.
Yes, Mupirocin+sucralfate may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor. Also, avoid using and consult a doctor if you experience increased irritation or redness.
Mupirocin+sucralfate is for topical use (for skin) only. Do not use Mupirocin+sucralfate on the face and avoid contact with eyes, nose, mouth and genitals. Do not put a bandage or a dressing on the affected area while using Mupirocin+sucralfate unless advised by the doctor.
No, please do not stop using Mupirocin+sucralfate without consulting your doctor even if you find symptomatic relief as discontinuing suddenly may worsen the infection or cause recurring symptoms. Therefore, complete the full course of Mupirocin+sucralfate as your doctor has prescribed it and if you experience any difficulty while using Mupirocin+sucralfate, please consult your doctor.
You are recommended to use Mupirocin+sucralfate for as long as your doctor has prescribed it or mentioned on the leaflet provided with the medicine. However, if the condition persists or worsens after using Mupirocin+sucralfate for 3-4 week, please consult a doctor.
Store Mupirocin+sucralfate at room temperature. Do not freeze and protect from heat. Keep Mupirocin+sucralfate away from sunlight and temperatures not exceeding 30°C.
