Naproxen Sodium+domperidone
About
Naproxen Sodium+domperidone belongs to the group of medications called 'analgesics'. It is primarily used in the treatment of migraine headaches. It can also treat pain associated with rheumatoid arthritis, arthritis, gout, dysmenorrhea (menstrual pain), and muscle and bone disorders, such as back pain, sprains, and strains. Migraine is a condition characterized by intense headaches. Pain is a symptom that occurs due to various underlying conditions.
Naproxen Sodium+domperidone is a combination of two drugs: Naproxen Sodium and Domperidone. Naproxen Sodium is a painkiller that works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) and prostaglandins (PG) responsible for pain and inflammation. Domperidone, on the other hand, is an anti-sickness medication. It inhibits communication between your digestive system and your brain, as well as between areas of your brain known as the chemoreceptor trigger zone (CTZ) and the vomiting centre. As a result, it assists you in stopping the feeling of being unwell (nausea or vomiting).
Take Naproxen Sodium+domperidone exactly as directed by your doctor. The dose and duration of Naproxen Sodium+domperidone may differ depending on the reason why you're taking it and your responses to treatment. The most common side effects of Naproxen Sodium+domperidone are dry mouth, confusion, headache, ringing in the ears, changes in vision, tiredness, dizziness, drowsiness, and rashes. These side effects are usually mild and go away by themselves. However, reach out to your doctor if the side effects are persistent or worsen.
Before taking this medicine, inform your doctor if you have any known allergy to Naproxen Sodium, Domperidone, other NSAIDs or other medications. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases or bleeding disorders should use Naproxen Sodium+domperidone only when prescribed by a doctor. Naproxen Sodium+domperidone may cause Feeling sleepy or tired. Feeling dizzy. So, it is advised not to drive or operate heavy machinery when taking Naproxen Sodium+domperidone. Naproxen Sodium+domperidone should be used in children below 12 years of age only when prescribed by a child specialist.
Uses of Naproxen Sodium+domperidone
Medicinal Benefits
Naproxen Sodium+domperidone is a combination of Naproxen sodium and Domperidone. Naproxen sodium is an anti-inflammatory (reduces inflammation) and analgesic (reduces pain) agent. It inhibits the synthesis of prostaglandins, which are inflammatory mediators, thereby reducing pain and inflammation. Domperidone acts by enhancing gastric peristalsis (movements) on an empty stomach. Easy movement of food through the stomach helps in relieving nausea and vomiting. It also blocks the dopamine receptors at the chemoreceptor trigger zone (responsible for regulating nausea and vomiting). Altogether Naproxen Sodium+domperidone eases the pain in various conditions.
Directions for Use
Storage
Side Effects of Naproxen Sodium+domperidone
- Dry mouth
- Headache
- Confusion
- Feeling sleepy or tired
- Feeling dizzy
- Ringing in the ears
- Changes in vision
- Rashes
In-Depth Precautions and Warning
Drug Warnings
Before using this Naproxen Sodium+domperidone, inform your doctor if you have any known allergies to Naproxen Sodium, Domperidone, other NSAIDs, or other drugs. Also, let the doctor know if you have a history of heart rhythm problems or ulcers caused by pain relievers. Patients over the age of 65, those with pre-existing cardiac diseases such as heart failure, myocardial infarction, ischemic heart disease, hypertension, or stroke, gastrointestinal bleeding (due to pain relievers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should only take Naproxen Sodium+domperidone if a doctor has prescribed it.
Drug Interactions
Drug-drug interactions: Naproxen Sodium+domperidone may interact with other NSAIDs (e.g. Ibuprofen, Aspirin), anticoagulants (e.g. warfarin), corticosteroids (e.g. prednisolone), diuretics (e.g. furosemide), antihypertensive medications (ramipril and amlodipine), antidepressants (e.g. citalopram), and medicines used to treat rheumatoid arthritis (e.g. methotrexate).
Drug-food interactions: Limit or quit the consumption of Alcoholic beverages.
Drug-disease interactions: Naproxen Sodium+domperidone may interact with disease conditions, including asthma, fluid retention (Congestive Heart Failure, Hypertension), GI toxicity (Gastrointestinal Haemorrhage, Gastrointestinal Perforation, Gastritis), rash, renal toxicities (Renal Dysfunction), and thrombosis (a condition in which a blood clot blocks a vein).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consuming alcohol while using Naproxen Sodium+domperidone.
Pregnancy
cautionNaproxen Sodium+domperidone should be used in pregnant women only if clinically needed. If you are pregnant, please consult your doctor before taking this medicine. Your doctor may prescribe Naproxen Sodium+domperidone if the benefits outweigh the risks.
Breast Feeding
safe if prescribedNaproxen Sodium+domperidone is considered safe to be used in breastfeeding. However, consult your doctor before taking this medicine if you are breastfeeding.
Driving
unsafeIt is unsafe to drive after taking Naproxen Sodium+domperidone as it impacts your ability to drive or operate machinery.
Liver
cautionLimited information was available for the use of Naproxen Sodium+domperidone in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Naproxen Sodium+domperidone in patients with liver impairment. It is not recommended for use in patients with severe liver disease.
Kidney
cautionLimited information was available for the use of Naproxen Sodium+domperidone in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using Naproxen Sodium+domperidone in patients with kidney impairment.
Children
cautionNaproxen Sodium+domperidone should be used in children below 12 years of age only when prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Drink plenty of fluids to avoid gastrointestinal problems.
- Avoid triggers that can increase your migraine headache.
- Take enough rest.
- Acupuncture, massage and physical therapy may also be helpful.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Avoid smoking and alcohol consumption.
- Performing yoga may also help in improving joint flexibility and pain management.
- Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
Special Advise
- Your doctor may monitor liver and kidney function if you take Naproxen Sodium+domperidone for the long-term.
- Taking meals at the same time every day and getting sufficient sleep might help in avoiding migraine attacks. You are recommended to avoid loud music, noisy places, extreme temperatures and bright light. Also, avoid consuming chocolates, cheese, processed food, smoking and alcohol.
Patients Concern
Disease/Condition Glossary
Migraine: Migraine is a condition characterized by intense headaches. It also causes nausea, vomiting, sensitivity to light and sound and difficulty speaking. Bright lights, strong smells, certain foods, loud sounds, stress and hormonal changes act as triggers for migraine. These triggers lead to acute attacks. Acute migraine attacks result in throbbing headaches and pain in the eyes, face or neck.
Pain: Pain is a widely used term to describe unpleasant feelings or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition.
Rheumatoid arthritis: Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.
Osteoarthritis: Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.
Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterized by cramps and pain during menstruation due to heavy flow. Pain, cramps and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Symptoms of dysmenorrhea include intense throbbing pain in the lower abdomen, dull, continuous ache, pain in the lower back and thighs, nausea, headache, and dizziness. The pain usually starts 1-3days before the period, peaks one day before the period starts and subsides 2-3days after the onset of the period.
FAQs
Naproxen Sodium+domperidone is a medication combination of Naproxen Sodium and Domperidone. Naproxen is a nonsteroidal anti-inflammatory medication (NSAID). It alleviates joint and muscular pain and swelling (inflammation). Domperidone, on the other hand, is an anti-sickness medication. It assists you in stopping the feeling of being unwell (nausea or vomiting).
Yes, Naproxen Sodium+domperidone may cause drowsiness. So, it is advised not to drive or operate heavy machinery when taking Naproxen Sodium+domperidone.
Naproxen Sodium+domperidone cannot permanently cure migraine. It can provide relief from pain and headache.
Naproxen Sodium+domperidone on prolonged or frequent use can cause liver or kidney problems. Therefore, it should be only used for a duration as prescribed by the doctor.
Dry mouth may be caused by Domperidone in Naproxen Sodium+domperidone. Chew a sugar-free sweet or sugar-free gum.
Naproxen Sodium+domperidone is usually not advised if you have stomach ulcers, bleeding in the stomach or intestines, or a hole in your stomach. If you have any concerns, please address them with your doctor.
