Naproxen+pantoprazole

Do not take Naproxen+pantoprazole if you are allergic to Naproxen+pantoprazole. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as naproxen may increase the risk of heart attack or stroke and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, older in age, alcoholic or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. Naproxen+pantoprazole is not recommended for pregnant women especially in the third trimester as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Naproxen+pantoprazole. Consult your doctor before giving Naproxen+pantoprazole to children. Do not take any other NSAIDs for pain relief along with Naproxen+pantoprazole unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like pantoprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using Naproxen+pantoprazole. Do not consume alcohol with Naproxen+pantoprazole as it may increase the risk of stomach bleeding or ulcer.

Drug-Drug Interactions: Naproxen+pantoprazole may have interaction with pain killers (ibuprofen, diclofenac, paracetamol, aspirin), high blood pressure-lowering medicines (propranolol, enalapril, cilazapril, losartan, candesartan, eprosartan), water pills (furosemide), blood thinners (heparin, warfarin, clopidogrel), fits related medicines (phenytoin), antidiabetic drugs (glimepiride, glipizide), antibiotics (moxifloxacin, ciprofloxacin, ampicillin, rifampicin), HIV/AIDS medicines (zidovudine, atazanavir, nelfinavir), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), heart medicine (digoxin) and anti-cancer drug (methotrexate).

Drug-Food Interactions: Naproxen+pantoprazole may interact with alcohol. Therefore, avoid alcohol intake while taking Naproxen+pantoprazole as it may increase the risk of stomach bleeding and drowsiness, and dizziness.

Drug-Disease Interactions: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver, or heart problems, and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever, and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting, and weight loss) should consult a doctor before taking Naproxen+pantoprazole.

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
• Acupuncture, massage, and physical therapy may also be helpful.
• Foods containing flavonoids such as soy, berries, broccoli, grapes, and green tea help in reducing inflammation.
• Include high-fiber-containing foods, berries, cherries, leafy green veggies, and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production.
• Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
• Avoid smoking and alcohol consumption.

• If you are elderly, a smoker, had stroke previously, or have high blood pressure, diabetes, or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.
• Your doctor may monitor liver function and kidney function if you are taking Naproxen+pantoprazole for long-term.
• Individuals at risk for osteoporosis-related fractures should receive an adequate intake of calcium and vitamin D.
• Pantoprazole in Naproxen+pantoprazole may interfere with certain laboratory tests (including urine test for tetrahydrocannabinol-THC, and a blood test to find certain tumors), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using Naproxen+pantoprazole.
• Regular monitoring of vitamin B-12, rarely, Pantoprazole in Naproxen+pantoprazole have caused vitamin B-12 deficiency. The risk is increased if they are taken Naproxen+pantoprazole every day for a long time.