Olmesartan Medoxomil+cilnidipine
About
Olmesartan Medoxomil+cilnidipine is a combination of blood pressure-lowering medicine, and novel calcium channel blockers primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.
Olmesartan Medoxomil+cilnidipine contains Olmesartan medoxomil and Cilnidipine. This combination helps lower raised blood pressure effectively. Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body.
It would be best if you take Olmesartan Medoxomil+cilnidipine with food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on the dose and duration based on your medical condition. You may experience headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Most of these side effects of Olmesartan Medoxomil+cilnidipine do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase the risk of getting stroke and heart disease. Olmesartan Medoxomil+cilnidipine should be taken with caution in patients with chest pain (angina), kidney disease, heart failure, low blood pressure (hypotension), and cardiogenic shock (sudden stopping of blood flow to the heart). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Olmesartan Medoxomil+cilnidipine can be prescribed accordingly. Please inform your doctor if you are taking any other medicines or are allergic to this medicine.
Uses of Olmesartan Medoxomil+cilnidipine
Medicinal Benefits
Olmesartan Medoxomil+cilnidipine contains Olmesartan medoxomil and Clindipine, which together help in lowering raised blood pressure effectively. Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.
Directions for Use
Storage
Side Effects of Olmesartan Medoxomil+cilnidipine
- Dizziness
- Headache
- Peripheral oedema (swelling of legs/hands)
- Flushing (skin reddening)
- Rash
- Taste change
- Upset stomach
In-Depth Precautions and Warning
Drug Warnings
Olmesartan Medoxomil+cilnidipine should not be given to people allergic to Olmesartan Medoxomil+cilnidipine, have low blood pressure (less than 90 mm of Hg), and also people who had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olmesartan Medoxomil+cilnidipine can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Olmesartan Medoxomil+cilnidipine and breastfeeding. Grapefruit juice and St. John's wort plant should not be consumed when taking Olmesartan Medoxomil+cilnidipine as it is contraindicated. Drinking alcohol while using Olmesartan Medoxomil+cilnidipine can cause you to have low blood pressure, so avoid intake of alcoholic beverages.
Drug Interactions
- Drug-Drug Interaction: Olmesartan Medoxomil+cilnidipine may interact with other high blood pressure-lowering pills (benazepril, metoprolol, ramipril, hydrochlorothiazide, simvastatin, diltiazem, aliskiren, verapamil, azilsartan, benazepril, lisinopril), and can lower your blood pressure leading to severe condition. Besides this, birth control pills containing drospirenone should not be taken with Olmesartan Medoxomil+cilnidipine.
- Drug-Food Interaction: Olmesartan Medoxomil+cilnidipine severely interacts with grapefruit, grapefruit juices, and St. John’s wort (a plant used to treat depression). Hence it should not be taken with Olmesartan Medoxomil+cilnidipine.
- Drug-Disease Interaction: Olmesartan Medoxomil+cilnidipine should not be given to people with chest pain (angina), cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, kidney problem, or heart failure
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeOlmesartan Medoxomil+cilnidipine can lower your blood pressure causing dizziness and drowsiness. It can also cause orthostatic hypotension (sudden fall in blood pressure while standing). So try to avoid intake of Olmesartan Medoxomil+cilnidipine with alcoholic beverages.
Pregnancy
unsafeOlmesartan Medoxomil+cilnidipine is pregnancy risk category D medicine which may cause harm to the fetus or unborn baby. So, when pregnancy is detected, discontinue Olmesartan Medoxomil+cilnidipine as soon as possible and consult the doctor.
Breast Feeding
cautionOlmesartan Medoxomil+cilnidipine passes into the breast milk. But its effect on the baby is not clear. However, contacting the doctor before intake of Olmesartan Medoxomil+cilnidipine is advisable.
Driving
unsafeOlmesartan Medoxomil+cilnidipine may cause side effects that could affect your ability to drive. Taking Olmesartan Medoxomil+cilnidipine may lower your blood pressure
Liver
cautionOlmesartan Medoxomil+cilnidipine to be taken with caution, especially if you have a liver disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Kidney
cautionOlmesartan Medoxomil+cilnidipine is not recommended in patients with chronic kidney disease (severe renal impairment). Please inform your doctor if you had a history of kidney disease. Your doctor may adjust the dose if required based on your condition.
Children
unsafeOlmesartan Medoxomil+cilnidipine is not recommended in children. The safety and efficacy of Olmesartan Medoxomil+cilnidipine in children have not yet been established
Habit Forming
Diet & Lifestyle Advise
- Keep your weight under control with a BMI of 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
- Opt for a diet rich in whole grains, fruits, vegetables and low-fat dairy products.
- Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
- If you are taking alcohol, then only one serving for women and two servings is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
- Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
Special Advise
Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.
Patients Concern
Disease/Condition Glossary
Blood pressure: It is the measurement of the force that our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
In case you have missed a dose of Olmesartan Medoxomil+cilnidipine, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time to take your next dose, then do not take both doses together. Take only one dose; a double dose of Olmesartan Medoxomil+cilnidipine will lead to low blood pressure.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can be increased at any time. If you have a persistent headache, please consult your doctor immediately.
Yes, Olmesartan Medoxomil+cilnidipine is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
