Olmesartan+metoprolol
About
Olmesartan+metoprolol is a combination of blood pressure-lowering medicine, primarily used to treat high blood pressure. Olmesartan+metoprolol contains Olmesartan (angiotensin receptor blocker) and Metoprolol (beta-blocker). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.
Olmesartan+metoprolol is a combination of two medicines, namely: Olmesartan and Metoprolol, which together helps in lowering raised blood pressure effectively. Olmesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Metoprolol (beta-blocker) helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.
You can take Olmesartan+metoprolol with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience headache, nausea, dizziness, increased potassium level, and low blood pressure. Most of these side effects of Olmesartan+metoprolol do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and can increase the risk of getting heart diseases and stroke. Inform your doctor if you are suffering from any kidney or liver or heart disease or are diabetic. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Olmesartan+metoprolol can be prescribed accordingly. It should not be given to the children less than 12 years of age. Do not use Olmesartan+metoprolol if you have low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to Olmesartan+metoprolol. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body. It would be best if you had regular potassium and electrolytes level check ups while taking Olmesartan+metoprolol for preventing any complications.
Uses of Olmesartan+metoprolol
Medicinal Benefits
Olmesartan+metoprolol is a combination of two medicines, namely: Olmesartan and Metoprolol, which together helps in lowering raised blood pressure effectively. Olmesartan is an angiotensin receptor blocker (ARB) which works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Metoprolol (beta-blocker) helps in relaxing our blood vessels by blocking the action of certain natural substances in your body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.
Directions for Use
Storage
Side Effects of Olmesartan+metoprolol
- Bradycardia (slow heart rate)
- Increased blood potassium level
- Cold extremities
- Gastrointestinal disturbances including nausea
- Fatigue
In-Depth Precautions and Warning
Drug Warnings
Don't stop taking Olmesartan+metoprolol without talking to your doctor first. Stopping Olmesartan+metoprolol gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Olmesartan+metoprolol if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to the children less than 12 years of age. Before taking Olmesartan+metoprolol, you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycaemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome). Prolonged use of Olmesartan+metoprolol may cause increased potassium level, so regular monitoring of serum potassium and electrolyte is essentially required.
Drug Interactions
Drug-Drug Interaction: Olmesartan+metoprolol may interact with other beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, nebivolol or sotalol), causing a dangerous drop in the heart rate. It also reacts with other anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril), asthma medications (theophylline), potassium salts, pain killers (ibuprofen). If you are using these medicines, tell your doctor before taking Olmesartan+metoprolol.
Drug-Food Interaction: Olmesartan+metoprolol interact with grapefruit and protein-enriched foods. Using Olmesartan+metoprolol together with ayurvedic, homoeopathy, unani, herbal supplements or any other OTC items may decrease the effects of Olmesartan+metoprolol. Hence, it is better to maintain at least 2 hours gap between the administration of Olmesartan+metoprolol and these products.
Drug-Disease Interaction: Olmesartan+metoprolol should not be given to the people with high potassium level, electrolyte imbalance, low blood pressure, diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Olmesartan+metoprolol to avoid unpleasant side-effects.
Pregnancy
unsafeOlmesartan+metoprolol should not be taken until prescribed. Olmesartan+metoprolol is a Category B pregnancy drug which is considered unsafe for pregnant women. Olmesartan+metoprolol can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast Feeding
safe if prescribedOlmesartan+metoprolol is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.
Driving
unsafeIt is not recommended to drive after taking Olmesartan+metoprolol as it may occasionally cause drowsiness or fatigue.
Liver
cautionOlmesartan+metoprolol to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionOlmesartan+metoprolol to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeOlmesartan+metoprolol is not recommended in children. The safety and efficacy of Olmesartan+metoprolol in children have not yet been established.
Habit Forming
Diet & Lifestyle Advise
- Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
- Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- If you are taking alcohol then only one serving for women and two servings for men is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
- Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
- Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.
Special Advise
- Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
- Check your blood pressure regularly and make sure your blood pressure does go below than normal, consult your doctor when needed.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up any time. If you have any discomfort, please consult your doctor immediately.
Usually, Olmesartan+metoprolol is prescribed for a long term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.
When you are taking a beta-blocker, your health care provider may recommend that you limit your consumption of bananas and other high potassium foods including papaya, tomato, avocado and kale.
Your doctor may probably tell you to stop taking Olmesartan+metoprolol as it lowers blood pressure (hypotension) when combined with general anesthesia before surgery. So, please inform your doctor before surgery if you are taking Olmesartan+metoprolol.
There is no clear cut clinical evidences that confirms Olmesartan+metoprolol increase an individual's body weight. However it can affect your body use energy and make you tired. If you are worried about your weight gain you can speak to the doctor.
Yes, Olmesartan+metoprolol can cause increased blood potassium level. It is recommended not to consume potassium rich diet or supplements while taking Olmesartan+metoprolol to avoid increase in blood potassium level.
It's unlikely that Olmesartan+metoprolol affects fertility in men or women. There's not enough evidence to say for certain. For best advise, consult your doctor.
Olmesartan+metoprolol may cause dizziness, if you are lying down or sitting get up slowly to avoid it. If you feel extremely dizzy, please consult your doctor and do as advised.
