Paracetamol+triprolidine+phenylephrine
About
Paracetamol+triprolidine+phenylephrine belongs to the class of medications called ‘cough and cold preparations’ used to treat the common cold and allergic symptoms such as the runny nose, sneezing, itchy or watery eyes, and blocked nose. The common cold is an infection of the nose and throat caused by viruses. Allergies are immune system reactions to foreign bodies or allergens such as certain foods, chemicals, pet dander, or pollen.
Paracetamol+triprolidine+phenylephrine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever). It works by inhibiting prostaglandin's production (chemical messengers) that are responsible for pain and fever. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels of nasal passage and airways.
You should take this medicine as prescribed by your doctor. The common side-effects of Paracetamol+triprolidine+phenylephrine are nausea, vomiting, dizziness, drowsiness, nervousness, and trouble sleeping. These side-effects are usually mild and don’t require medical attention. However, consult your doctor immediately if any of these side-effects persist or get worsen.
Do not use Paracetamol+triprolidine+phenylephrine if you are allergic to Paracetamol, Triprolidine, Phenylephrine, or any other contents in it. Paracetamol+triprolidine+phenylephrine is not recommended for use in patients suffering from constipation, inability to urinate, stomach blockage, uncontrolled asthma, glaucoma (increased pressure in the eye), high blood pressure, heart diseases, hyperthyroidism (overactive thyroid), diabetes, or intolerance to sugars. Do not take Paracetamol+triprolidine+phenylephrine if you have taken MAO inhibitors (antidepressants) in the last 14 days. Inform your doctor if you are pregnant or breastfeeding.
Uses of Paracetamol+triprolidine+phenylephrine
Medicinal Benefits
Paracetamol+triprolidine+phenylephrine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol is an analgesic (relieves pain) and works by inhibiting the production of prostaglandins (chemical messengers) that are responsible for pain. It also has an antipyretic effect (reduces fever). Triprolidine is an antihistamine (anti-allergic drug) that blocks histamine, a substance responsible for causing allergic reactions. It also provides relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels of nasal passage and airways. Together, Paracetamol+triprolidine+phenylephrine can effectively reduce the symptoms of common cold and allergies.
Directions for Use
Storage
Side Effects of Paracetamol+triprolidine+phenylephrine
- Nausea
- Vomiting
- Dizziness
- Drowsiness
- Nervousness
- Trouble sleeping
- Blurred vision
- Dry mouth
In-Depth Precautions and Warning
Drug Warnings
Paracetamol+triprolidine+phenylephrine should be used with caution in patients with breathing problems, glaucoma (increased pressure in the eye), heart problems, hypertension (high blood pressure), kidney problems, liver disease, seizures (fits), stomach blockage), hyperthyroidism (overactive thyroid), and an enlarged prostate gland (difficulty urinating). Paracetamol+triprolidine+phenylephrine contains sucrose, so use this medicine with caution in patients with diabetes and intolerance to sugars. Paracetamol+triprolidine+phenylephrine may cause drowsiness, so do not take alcohol as it causes excessive drowsiness. Also, do not drive or operate heavy machinery if you are drowsy. It should be used with caution in children and elderly patients as they are more prone to side-effects. Do not take Paracetamol+triprolidine+phenylephrine if you have taken antidepressants or medicines to treat Parkinson’s disease in the last 14 days.
Drug Interactions
Drug-Drug Interactions: Paracetamol+triprolidine+phenylephrine may interact with other antihistamines (cetirizine and diphenhydramine), medicines used to treat high blood pressure (guanethidine, methyldopa, atenolol, and nifedipine), anticoagulant (warfarin), a medicine used to treat high cholesterol (cholestyramine), a medicine used to treat HIV (zidovudine), anti-emetic drugs (domperidone and metoclopramide), MAO inhibitors (isocarboxazid. linezolid, methylene blue, phenelzine, selegiline, and tranylcypromine, etc.), birth control pills, medications used to treat cough (codeine and hydrocodone), sedatives (alprazolam, lorazepam, and zolpidem), and muscle relaxants (carisoprodol and cyclobenzaprine).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Paracetamol+triprolidine+phenylephrine should be used with caution in patients with constipation, inability to urinate, a stomach blockage, uncontrolled asthma, diabetes, glaucoma (increased pressure in the eye), high blood pressure, heart diseases, and hyperthyroidism (overactive thyroid).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol consumption may increase the risk of side-effects such as drowsiness.
Pregnancy
unsafeParacetamol+triprolidine+phenylephrine is a category C medicine and may cause toxic effects to the unborn baby. When clinically needed, Paracetamol+triprolidine+phenylephrine is given to pregnant women after doing a risk/benefit assessment by a doctor.
Breast Feeding
unsafeParacetamol+triprolidine+phenylephrine may pass into breast milk. So, it should be used with caution in breastfeeding mothers.
Driving
cautionParacetamol+triprolidine+phenylephrine may cause drowsiness. So, avoid driving or operating heavy machinery while using this medicine if you are drowsy.
Liver
cautionParacetamol+triprolidine+phenylephrine should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionParacetamol+triprolidine+phenylephrine should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
cautionParacetamol+triprolidine+phenylephrine should be used with caution in children as they are more prone to side-effects. The dose may have to be adjusted by your doctor.
Habit Forming
Diet & Lifestyle Advise
- Staying hydrated is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate cough, runny nose, and sneezing.
- The immune system is affected by stress and raises the risk of being sick. An individual can exercise regularly, meditate, do deep breathing, and try progressive muscle relaxation techniques to relieve stress.
- To stay fit and safe, try to sleep at least 8 hours each night.
- It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
Special Advise
Paracetamol+triprolidine+phenylephrine may interfere with certain laboratory tests such as brain scan for Parkinson's disease and urine drug screening tests, leading to false test results. So, inform your doctor that you are using this medicine before undergoing the tests.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.
Allergies: It occurs when foreign elements that cause allergy-causing agents (allergens) attack and invades our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Paracetamol+triprolidine+phenylephrine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol blocks the action of chemical messengers that cause pain and fever. Triprolidine blocks the action of histamines that cause allergic reactions. Phenylephrine reduces swelling of the blood vessels in the nasal passages. Together, Paracetamol+triprolidine+phenylephrine can effectively treat symptoms of allergy and the common cold.
Paracetamol+triprolidine+phenylephrine may cause drowsiness and dizziness. So, it is advised to refrain from activities such as driving or operating heavy machinery until you are alert.
It is not recommended to use cetirizine along with Paracetamol+triprolidine+phenylephrine as it may increase side-effects such as drowsiness and dizziness. So, it is advised to consult a doctor before using any medicines while taking Paracetamol+triprolidine+phenylephrine.
Paracetamol+triprolidine+phenylephrine should not be used if you have taken antidepressants or drugs used to treat Parkinson's disease in the last 14 days. So, it is always advised to inform your doctor about all the prescription, non-prescription, and dietary supplements you are taking, to identify any interactions with the Paracetamol+triprolidine+phenylephrine.
Paracetamol+triprolidine+phenylephrine can effectively treat and provide relief from allergic symptoms such as sneezing, runny/stuffy nose, throat irritation, or watery eyes.
