Pepsin+diastase
About
Pepsin+diastase is a digestive aid primarily used to treat the digestive disorder and proper digestion of starch or carbohydrate in the die into a simpler form of sugar/carbohydrate. It is also an appetite stimulant (increases hunger) that effectively treats acid indigestion (heartburn), flatulence (gas), epigastric distress (upper abdominal pain), and eructation (burping). Pepsin+diastase can also be used to relieve other digestive disorders like pancreatic insufficiency (inability to produce pancreatic enzymes) and abdominal discomfort. Indigestion is the inability to digest the complex form of food associated with the sour stomach, gas formation with mild pain/discomfort in the stomach.
Pepsin+diastase contains two digestive enzymes, namely: Diastase and Pepsin. Diastase is a starch hydrolysing enzyme that breaks down complex carbohydrate (polysaccharides, i.e. starch) into simple carbohydrates (monosaccharides, i.e. simple sugar). It promotes digestion in cases of chronic illness, stomach fullness, flatulence, and indigestion. On the other hand, Pepsin is a protein-digesting enzyme that helps break down larger protein molecules into smaller units of protein (amino acids). Thus together, Pepsin+diastase aid digestive disorder and gastric problems.
Take Pepsin+diastase in the dose and duration advised by your physician based on your medical condition. Pepsin+diastase is generally safe to use. However, some may experience side effects like abdominal pain, feeling of sickness, skin rash, stomach upset, diarrhea, painful urination, heartburn, nausea and vomiting. Although not everyone experiences these side effects, if they occur, please seek medical attention.
Let your physician know if you are using any others medicines, herbal or vitamin supplements before you take Pepsin+diastase. Inform your doctor if you have any allergic reactions to pork protein before starting Pepsin+diastase. If you a history of inflammation/swelling of the pancreas (acute pancreatitis), let your doctor know about it. Oral syrup of Pepsin+diastase is to be cautiously administered in diabetic patients since it may contain sucrose. You can try opting for sugar-free formulations. Intake of probiotics, prebiotics, and plenty of fluids is recommended if you are suffering from indigestion. Pregnant and breastfeeding women should use Pepsin+diastase with proper consultation and caution.
Uses of Pepsin+diastase
Medicinal Benefits
Pepsin+diastase helps in relieving digestive disorders like indigestion, heartburn, gas, and abdominal discomfort. It contains two digestive enzymes, namely: Diastase and Pepsin. Fungal diastase is a starch hydrolysing or amylolytic enzyme that breaks down the starch into simple sugars (maltose) for easy digestion of carbohydrates, fats and proteins. Pepsin is a proteolytic enzyme (protein-digesting) that breaks down larger protein molecules into smaller proteins (amino acids). Thus, Pepsin+diastase promotes the digestion of carbohydrates and proteins and helps absorb the intestine's essential nutrients.
Directions for Use
Storage
Side Effects of Pepsin+diastase
- Abdominal pain
- Feeling of sickness
- Skin rash
- Stomach upset
- Diarrhoea
- Painful urination
- Heartburn
- Nausea
- Vomiting
In-Depth Precautions and Warning
Drug Warnings
If you a history of swelling/inflammation of the pancreas (acute pancreatitis), let your physician know about it. Oral syrup of Pepsin+diastase is to be cautiously administered in diabetic patients since it may contain sucrose, instead, you can try sugar-free formulations. Sleep with your head elevated (at least 6 inches) above your feet can decrease the acid reflux symptoms. Intake of probiotics, prebiotics, and plenty of fluids is recommended if you are suffering from indigestion. It is not known if Pepsin+diastase is excreted into the breast milk. So, pregnant and breastfeeding women should use Pepsin+diastase with proper consultation and caution. Alcohol consumption and smoking can make the stomach produce more acid, leading to heartburn, so avoid its usage during treatment.
Drug Interactions
Drug-Drug Interaction: Pepsin+diastase may interact with anti-diabetic drugs (acarbose and miglitol).
Drug-Food Interaction: Alcohol consumption makes the stomach to produce more acid, which can further lead to heartburn.
Drug-Disease Interaction: Pepsin+diastase should be used cautiously if you have any liver or kidney diseases, diabetes, and swelling/inflammation of the pancreas (acute pancreatitis).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is recommended to avoid alcohol while you are being treated with Pepsin+diastase. Alcohol consumption makes the stomach to produce more acid, which can further lead to heartburn.
Pregnancy
cautionThere is limited data on how the Pepsin+diastase affects pregnancy. Pepsin+diastase should be used during pregnancy only if the benefit outweighs the risk. Please consult your physician if you are planning to become pregnant or already pregnant before starting Pepsin+diastase.
Breast Feeding
cautionIt is unclear if Pepsin+diastase is excreted into the breast milk while used by a breastfeeding mother. It is better to consult your physician before taking Pepsin+diastase if you are breastfeeding.
Driving
cautionDo not drive or operate machinery if you experience any discomfort while using Pepsin+diastase until you feel better.
Liver
cautionPlease take Pepsin+diastase with caution and physician advice if you have a history of liver diseases/conditions. Your dose may be adjusted in case of any liver impairment.
Kidney
cautionPlease take Pepsin+diastase with caution and physician advice if you have a history of kidney diseases/conditions. Your dose may be adjusted in case of any renal impairment.
Children
cautionYour physician will decide the dose based on your child’s age and body-weight.
Habit Forming
Diet & Lifestyle Advise
- Please take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
- Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas to aid digestion.
- Avoid intake of alcoholic beverages with Pepsin+diastase as it can make you dehydrated and increase acidity.
- Avoid eating too much, eating too fast, eating high-fat foods, or eating during stressful situations that can burden your stomach.
- Eating small meals at regular intervals so that stomach does not have to work as hard or as long.
- Smoking can irritate the stomach lining, hence please avoid it.
- Sleep with your head elevated (at least 6 inches) above your feet, and use pillows. This helps digestive juices to flow into the intestines rather than to the oesophagus.
Special Advise
Monitor your blood sugar levels regularly since sucrose levels in the syrup may affect your glucose levels in diabetes. Instead, ask your physician to advise sugar-free formulations.
Patients Concern
Disease/Condition Glossary
Dyspepsia (indigestion): Indigestion is the inability to digest the food associated with pain and discomfort in the stomach.
Eructation: Also known as belching or burping. It releases gas from the upper digestive tract (oesophagus and stomach) through the mouth.
Pancreatic Insufficiency: It is a digestive disorder characterized by a deficiency of pancreatic enzymes to break down food in the intestine.
FAQs
Pepsin+diastase contains diastase and Pepsin. Diastase is a starch hydrolysing or amylolytic enzyme that breaks down the starch into simple sugars (maltose). Pepsin is a proteolytic enzyme (protein-digesting) that breaks down larger protein molecules into smaller peptides (a short chain of amino acids). Collectively, Pepsin+diastase promotes the digestion of carbohydrates and proteins and helps absorb the essential nutrients in the intestine.
Please let your doctor know if you have a history of allergic reactions to medicines, and inflammation of the pancreas (pancreatitis) before starting Pepsin+diastase.
Syrup formulation of Pepsin+diastase is to be cautiously administered in diabetic patients since it may contain sucrose. It is advised to consult your physician before using Pepsin+diastase and monitor your blood sugar levels regularly. Your physician may advise you sugar-free formulations.
Do not stop using Pepsin+diastase even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the disease may not be cured completely.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Yes, digestive disorders and starch degrading enzyme are among the most common reported uses for Pepsin+diastase. Pepsin+diastase should be used only after a physician suggestion.
