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Rabeprazole+calcium

About

Rabeprazole+calcium is a combination drug containing 'antiulcer medicine,' called proton pump inhibitors used to treat duodenal ulcers and benign stomach ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Rabeprazole+calcium contains Raberprazole and Calcium, primarily used to treat ulcers of the stomach. Rabeprazole works by blocking the action of the enzyme known as the gastric proton pump responsible for the production of acid. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. Calcium helps to reduce bone loss, which occurs due to rabeprazole and increases bone mineral density. So, collectively both of them help to treat ulcers effectively.

Take Rabeprazole+calcium as prescribed by your doctor. You are advised to take Rabeprazole+calcium for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Rabeprazole+calcium 30 minutes before food. In some cases, you may experience certain common side effects such as headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, flu-like symptoms, back pain, aches, infection, difficulty sleeping, cough, sore throat, and runny nose. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Inform your doctor before taking Rabeprazole+calcium if you have a stomach tumour, liver disease or if you are due to have Chromogranin A blood test. On long-term treatment, Rabeprazole+calcium may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures. Do not take Rabeprazole+calcium if you are pregnant or breastfeeding. Rabeprazole+calcium may cause dizziness and sleepiness, so drive only if you are alert. Rabeprazole+calcium should not be given to children as safety has not been established. Avoid consuming alcohol and Rabeprazole+calcium as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Rabeprazole+calcium

Gastro-oesophageal reflux disease (GERD), duodenal ulcers, benign stomach ulcer, Zollinger-Ellison syndrome

Medicinal Benefits

Rabeprazole+calcium is a combination drug containing 'antiulcer medicines,' called proton pump inhibitors used to treat duodenal ulcers,  benign stomach ulcer, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic and Zollinger-Ellison syndrome. Rabeprazole+calcium contains Rabeprazole and Calcium. Rabeprazole works by blocking the action of the enzyme known as gastric proton pump responsible for the production of acid. This reduces the amount of acid produced, heals the ulcers and prevents the formation of new ulcers. Calcium helps to reduce bone loss, which occurs due to rabeprazole and increases bone mineral density. So, collectively both of them help to treat ulcers effectively.

Directions for Use

Take Rabeprazole+calcium with or without food or as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rabeprazole+calcium

  • Headache
  • Dizziness
  • Diarrhoea
  • Constipation
  • Nausea
  • Vomiting
  • Flatulence (wind) 
  • Flu-like symptoms

In-Depth Precautions and Warning

Drug Warnings

Do not take Rabeprazole+calcium if you are allergic to any of its contents. Inform your doctor before taking Rabeprazole+calcium if you have a stomach tumour, liver disease or if you are due to have Chromogranin A blood test. On long-term treatment, Rabeprazole+calcium may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures. The doctor may advise regular tests to monitor your condition. Do not take Rabeprazole+calcium if you are pregnant or breastfeeding. Rabeprazole+calcium may cause dizziness and sleepiness, so drive only if you are alert. Rabeprazole+calcium should not be given to children as safety has not been established. Avoid consuming alcohol and Rabeprazole+calcium as it could lead to increased drowsiness and elevate stomach acid production. Prolonged intake of Rabeprazole+calcium is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug Interactions

Drug-Drug Interactions: Rabeprazole+calcium may have interaction with a pain killer (aspirin, naproxen), anti-depressant (duloxetine, amitriptyline), blood thinner (clopidogrel), a drug used to treat hypothyroidism (levothyroxine), anti-HIV (atazanavir), anti-fungal (ketoconazole, itraconazole), anti-cancer (methotrexate), vitamin (cyanocobalamin), and Medicines to help you to sleep or feel more relaxed (such as diazepam or zolpidem).

Drug-Food Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

Drug-Disease Interactions: Rabeprazole+calcium may have interactions with Clostridium difficile-associated diarrhoea, liver disease, bone fractures and hypomagnesemia (low magnesium levels).

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • NAPROXEN
  • DULOXETINE
  • AMITRIPTYLINE
  • CLOPIDOGREL
  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE
  • CYANOCOBALAMIN
  • DIAZEPAM
  • ZOLPIDEM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Rabeprazole+calcium. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

    • Safety Warning

      Pregnancy

      unsafe

      Do not take Rabeprazole+calcium if you are pregnant or planning for pregnancy. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

    • Safety Warning

      Breast Feeding

      unsafe

      Do not take Rabeprazole+calcium if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Driving

      caution

      Rabeprazole+calcium may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Rabeprazole+calcium should not be given to children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat smaller meals more often.
    • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
    • Maintain a healthy weight by regular exercising.
    • Avoid lying down after eating to prevent acid reflux.
    • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
    • Practice relaxation techniques and avoid stress by doing yoga or meditation.
    • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
    • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

    Special Advise

    • Inform your doctor before taking Rabeprazole+calcium if you are due to have Chromogranin A blood test.
    • Rabeprazole+calcium may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Rabeprazole+calcium.

    Patients Concern

    Disease/Condition Glossary

    Gastroesophageal reflux disease (GERD): The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

    Duodenal ulcer: It is a painful condition followed by the development of sores or ulcers in the duodenum or stomach lining (first part of the small intestine, i.e., the duodenum).

    Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

    FAQs

    Rabeprazole+calcium is an anti-ulcer medication. Rabeprazole works by blocking the action of the enzyme known as gastric proton pump responsible for the production of acid. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. Calcium helps to reduce bone loss, which occurs due to rabeprazole and increases bone mineral density. So, collectively both of them help to treat ulcers effectively.

    Diarrhoea might be a side-effect of Rabeprazole+calcium. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Prolonged intake of Rabeprazole+calcium is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

    On long term treatment, Raberprazole present in Rabeprazole+calcium might increase the risk of fractures of the hip, spine, and wrist. But calcium present in Rabeprazole+calcium helps to minimize bone loss and maintains the bone mineral density.

    Talk to your doctor if you do not feel better even after taking Rabeprazole+calcium for 14 days. Do not take Rabeprazole+calcium for longer durations unless prescribed by the doctor. If Rabeprazole+calcium is prescribed for longer durations, a regular check-up is advised.

    Avoid or limit the consumption of alcohol while taking Rabeprazole+calcium as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

    Available Medicines for

    Rabeprazole+calcium

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