Rabeprazole+itopride
About
Rabeprazole+itopride is a combination medicine of proton pump inhibitor and prokinetic agent used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.
Rabeprazole+itopride is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain that is responsible for controlling vomiting. It increases gastric emp undying improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabeprazole+itopride helps prevent acid reflux, thereby relieving acidity.
Take Rabeprazole+itopride 30-60 minutes before food. Do not chew or break the tablet; swallow it as a whole with a glass of water. You are advised to take Rabeprazole+itopride for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor before taking Rabeprazole+itopride if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, Rabeprazole+itopride may cause osteoporosis and hypomagnesemia (low levels of magnesium). Do not take Rabeprazole+itopride if you are pregnant or breastfeeding unless prescribed by the doctor. Rabeprazole+itopride causes drowsiness, so drive only if you are alert. Rabeprazole+itopride should not be given to children as safety has not been established. Avoid consuming alcohol with Rabeprazole+itopride as it can lead to increased drowsiness and increased acid production.
Uses of Rabeprazole+itopride
Medicinal Benefits
Rabeprazole+itopride is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting. It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabeprazole+itopride helps prevent acid reflux, thereby relieving acidity.
Directions for Use
Storage
Side Effects of Rabeprazole+itopride
- Nausea
- Dizziness
- Diarrhoea
- Headache
- Stomach pain
In-Depth Precautions and Warning
Drug Warnings
Do not take Rabeprazole+itopride if you are allergic to any of its contents. Inform your doctor before taking Rabeprazole+itopride if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. Rabeprazole+itopride may cause osteoporosis on long-term treatment. Rabeprazole+itopride may also cause hypomagnesemia (low magnesium). Do not take Rabeprazole+itopride if you are pregnant or breastfeeding unless prescribed by the doctor. Rabeprazole+itopride causes dizziness, so drive only if you are alert. Rabeprazole+itopride should not be given to children as safety has not been established. Avoid consuming alcohol along with Rabeprazole+itopride as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about all the medicines and your health condition to rule out any side effects. Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Rabeprazole+itopride may cause osteoporosis and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.
Drug Interactions
DRUG-DRUG INTERACTIONS: Rabeprazole+itopride may have interaction with pain killers (aspirin, naproxen), an antidepressant (duloxetine), hypothyroidism (levothyroxine), statins (atorvastatin), blood thinner (clopidogrel), and vitamin (vitamin b12).
FOOD-DRUG INTERACTIONS: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
DRUG-DISEASE INTERACTION: Rabeprazole+itopride may have interactions with gastrointestinal bleeding, mechanical obstruction or perforation, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Rabeprazole+itopride. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Pregnancy
cautionConsult your doctor before taking Rabeprazole+itopride if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor before taking Rabeprazole+itopride; your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
cautionRabeprazole+itopride causes dizziness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed. Consult your doctor before taking Rabeprazole+itopride if you have a liver impairment or any concerns.
Kidney
cautionDose adjustment may be needed. Consult your doctor before taking Rabeprazole+itopride if you have kidney impairment or any concerns.
Children
unsafeRabeprazole+itopride should not be given to children as safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
- Maintain a healthy weight by regular exercising.
- Avoid lying down after eating.
- Avoid tight-fitting clothes.
- Maintain a healthy weight by regular exercising.
- Practice relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
- Avoid sitting continuously, as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.
Special Advise
- Inform your doctor before taking Rabeprazole+itopride if you are due to have Chromogranin A test.
- Regular tests of magnesium and calcium are suggested if you are regularly taking prescribed Rabeprazole+itopride.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like GERD, acidity, and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste, and difficulty swallowing. Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
FAQs
Rabeprazole+itopride is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI), that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting. It increases gastric emptying, and improves gastric sensitivity and tension by increasing the movement of the stomach, and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabeprazole+itopride helps prevent acid reflux and provide relief from acidity.
Talk to your doctor if you do not feel better even after taking Rabeprazole+itopride for 14 days. Do not take Rabeprazole+itopride for longer durations unless prescribed by the doctor.
Diarrhoea might be a side-effect of Rabeprazole+itopride. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Avoid or limit the consumption of alcohol while taking Rabeprazole+itopride as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Rabeprazole+itopride contains lactose monohydrate, so a person who is intolerant to sugar should tell their doctor before taking this medicine.
Consult your doctor before taking Rabeprazole+itopride if you are pregnant or planning for pregnancy. Your doctor will prescribe Rabeprazole+itopride only if the benefits outweigh the risks.
