Rabeprazole+mosapride

Do not take Rabeprazole+mosapride if you are allergic to any of its contents, have a gastrointestinal hemorrhage, porphyria (liver disorder) and cardiac impairment. Inform your doctor before taking Rabeprazole+mosapride if you have stomach pain, indigestion, vomiting food or blood or if you pass black stools,  have severe liver or kidney problems, if you are due to have Chromogranin A test. Do not take Rabeprazole+mosapride if you are pregnant or breastfeeding unless prescribed by the doctor. Rabeprazole+mosapride should not be given to children as safety has not been established. Rabeprazole+mosapride should be used with extreme caution in elderly patients since the risk of side effects is high. Rabeprazole+mosapride may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment, the doctor may advise regular tests for monitoring your condition. Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using Rabeprazole+mosapride. Rabeprazole+mosapride may cause dizziness and drowsiness, so drive only if you are alert. Avoid consuming alcohol along with Rabeprazole+mosapride as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions: Rabeprazole+mosapride may have interaction with a pain killer (ibuprofen, diclofenac, aspirin, naproxen), anti-depressant (duloxetine, amitriptyline), blood thinner (clopidogrel, heparin, warfarin), a drug used to treat hypothyroidism (levothyroxine), anti-HIV (atazanavir, nelfinavir), anti-fungal (ketoconazole, itraconazole, voriconazole, posaconazole), anti-cancer (methotrexate), vitamin (cyanocobalamin), medicines to help you to sleep or feel more relaxed (diazepam, zolpidem).

Drug-Food Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn. Rabeprazole+mosapride may have interaction with St.John’s wort (herbal supplement used to treat depression). 

Drug-Disease Interactions: Rabeprazole+mosapride may have interactions with gastrointestinal bleeding, intestinal obstruction, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).

• Eat smaller meals more often.
• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
• Maintain a healthy weight by regular exercising.
• Avoid lying down after eating as it causes acid reflux.
• Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
• Practice relaxation techniques and avoid stress by doing yoga or meditation.
• Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
• Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

• Inform your doctor before taking Rabeprazole+mosapride if you are due to have Chromogranin A test.
• Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause diarrhoea, autoimmune disease (lupus), and brittle bones. So tell your doctor if you have these symptoms.
• Patients with a history of gastrointestinal bleeding or ulcer, movement disorders, or mechanical obstruction, or perforations (holes) in the intestine should avoid using Rabeprazole+mosapride and contact their doctor before using it.