RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR
About
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR belongs to the group of growth factors used in the treatment of diabetic foot ulcers, bedsores, chronic leg ulcers, and vascular ulcers. A diabetic foot ulcer is an open wound in diabetic patients that occurs due to uncontrolled diabetes. It appears as a red crater on the skin. It mostly affects the bottom or top of the foot and tip of a toe.
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR contains recombinant human epidermal growth factor which is a protein that stimulates cell growth. It acts by releasing a growth factor that can promote tissue repair, skin regeneration (formation of healthy skin), and accelerate wound healing. These effects help to reduce skin ulcers in diabetic foot ulcer patients.
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR is meant for external use. RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR should be applied as a thin layer with a sterile cotton swab. In some cases, RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR may cause certain common side effects such as headache, nausea, rash, stomach pain, and pruritis. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to any of the components in RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR. Avoid RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR if you are immune-compromised, pregnant or breastfeeding. Inform your doctor if you are on treatment with corticosteroids, immunosuppressants or immunostimulators. Keep your doctor informed about your health condition and medications. Discuss your entire vaccination history with your doctor.
Uses of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR
Medicinal Benefits
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR contains recombinant human epidermal growth factor, an endogenous growth factor that helps in wound healing and new cell production. It is a glycoprotein that binds to epidermal growth factor receptors, enhancing the processes responsible for cellular proliferation, new cell production, collagen synthesis, and reduced cell death, thereby amplifying wound healing and finding major application in the treatment of diabetic foot ulcers, bedsore, chronic leg ulcers and vascular ulcers.
Directions for Use
Storage
Side Effects of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR
- Headache
- Abdominal pain
- Nausea
- Rash
- Pruritis
In-Depth Precautions and Warning
Drug Warnings
It is advisable to inform the doctor if you are allergic to any of the components in RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR. Keep your doctor informed if you suffer from hypersensitivity. Avoid RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR in case of an immunocompromised state such as HIV. Inform your doctor if you are on treatment with any corticosteroids, or are on any vaccines, immunosuppressants or immunostimulators. Avoid using RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR if you are pregnant or breastfeeding.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are using any other medicines.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR should be used with caution in patients with a known hypersensitivity disorder and HIV.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThere is not enough literature on the effects of alcohol on RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR. Exercise caution before taking alcohol with RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR. Please consult your doctor if you have any concerns.
Pregnancy
unsafeRECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR is not recommended for use by pregnant women. Please consult your doctor if you have any concerns.
Breast Feeding
unsafeRECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR is not recommended during nursing. Please consult your doctor if you have any concerns.
Driving
safe if prescribedRECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR is unlikely to affect your ability to drive.
Liver
cautionPlease consult your doctor in case of any concerns.
Kidney
cautionPlease consult your doctor in case of any concerns.
Children
cautionLimited information is available. Please consult a doctor.
Habit Forming
Diet & Lifestyle Advise
- Limit the intake of salt and sugar in your diet. Keep your blood sugar under control.
- Cut back on foods that are high in fat and cholesterol. Eat more fruits, vegetables and whole-grain foods.
- Avoid tobacco use and smoking as this may aggravate your diabetic condition.
- It is important to wear appropriate footwear in case of a diabetic foot ulcer.
- Always use footwear indoors as well.
- Have your toenails cut off regularly by a trained pedicurist.
- Wash and dry your feet at least once every day in lukewarm water, paying special attention to the area between the toes.
Special Advise
Patients Concern
Disease/Condition Glossary
Diabetic Foot Ulcer: A diabetic foot ulcer is an open sore or wound seen on the foot of patients suffering from high and uncontrolled blood sugar. It is a painful condition and makes it difficult for them to rest their feet. It is a major complication of diabetes mellitus. It occurs when the diabetes level becomes uncontrollable due to inadequate treatment. In this condition, the skin tissues break down and expose the skin layer's inner parts, which appear as a red crater in the skin. There is also damage to the nerves and decreased blood supply to the damaged foot, which further delays wound healing.
FAQs
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR works by enhancing wound healing, new cell production and collagen synthesis, thereby reducing the time taken for skin to restore and heal.
The absorption of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR is quite rapid. The longer you have it on, the quicker it will absorb into your body. Speak to your doctor in case of any concerns.
Skin-type does not have an effect on RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR and is indicated for all skin types. Please consult a skin doctor for further concerns.
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR is for external use only. Do not use it on skin rashes or lesions without discussing it with your doctor. Do not use any heating pads on the feet. Make sure the wound is cleaned properly before applying RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR.
RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR might not be recommended in case of an immunocompromised state such as HIV as it contains an active biological material. However, your doctor will prescribe an alternate treatment plan in case you suffer from HIV. Clear any concerns with your doctor.
