SERRATIOPEPTIDASE+NIMESULIDE
About
SERRATIOPEPTIDASE+NIMESULIDE belongs to a class of medication called non-steroidal anti-inflammatory drugs (NSAIDs) primarily used to treat acute pain in people above 12 years of age. It is used to reduce pain and swelling in osteoarthritis, rheumatoid arthritis, primary dysmenorrhoea (painful periods or menstrual cramps), back pain, muscle pain, pain in the throat and ear, toothache, and third molar surgery. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. While chronic pain lasts for a long duration and is caused due to nerve damage, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc.
SERRATIOPEPTIDASE+NIMESULIDE is a combination of two drugs, namely: Serratiopeptidase and Nimesulide. Serratiopeptidase is an enzyme that helps break the insoluble protein known as fibrin (a by-product of a blood clot) into smaller units (amino acids). Nimesulide is a non-steroidal anti-inflammatory drug (pain reliever) that prevents prostaglandins' release (a chemical associated with pain and swelling). Thus, together it helps in reducing inflammation, pain, and formation of mucus at the affected site.
Take SERRATIOPEPTIDASE+NIMESULIDE as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience vomiting, nausea, diarrhoea, or an increase in liver enzymes. Most of these side effects of SERRATIOPEPTIDASE+NIMESULIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to SERRATIOPEPTIDASE+NIMESULIDE or any other medicines, please tell your doctor. SERRATIOPEPTIDASE+NIMESULIDE is not recommended for children below 12 years of age. SERRATIOPEPTIDASE+NIMESULIDE is not recommended for pregnant women, especially in the third trimester as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking SERRATIOPEPTIDASE+NIMESULIDE. SERRATIOPEPTIDASE+NIMESULIDE should be used with caution in elderly people as it may increase the risk of severe gastrointestinal bleeding. If you develop flu-like symptoms or fever, you are advised to stop taking SERRATIOPEPTIDASE+NIMESULIDE and consult a doctor. If you have Lapp lactase deficiency, galactose intolerance, or glucose-galactose malabsorption, avoid taking SERRATIOPEPTIDASE+NIMESULIDE. If you have high blood pressure, fluid retention, alcoholism, drug addiction, gastrointestinal bleeding, severe heart failure, bleeding disorders, stomach ulcer, or severe kidney or liver problems, inform your doctor before taking SERRATIOPEPTIDASE+NIMESULIDE.
Uses of SERRATIOPEPTIDASE+NIMESULIDE
Medicinal Benefits
SERRATIOPEPTIDASE+NIMESULIDE is a combination of two drugs, namely: Serratiopeptidase and Nimesulide. Serratiopeptidase is a proteolytic enzyme that helps break the insoluble protein's breakdown (fibrin, a by-product of a blood clot) into smaller units. It also causes thinning of the body's fluids due to injury, thereby making fluid drainage smoother in the swollen tissue. Thereby, it promotes healing. Nimesulide is a non-steroidal anti-inflammatory drug (pain reliever) that prevents the release of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, helps in relieving pain and swelling.
Directions for Use
Storage
Side Effects of SERRATIOPEPTIDASE+NIMESULIDE
- Vomiting
- Nausea
- Diarrhoea
- Increase in liver enzymes
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to SERRATIOPEPTIDASE+NIMESULIDE or any other medicines, please tell your doctor. SERRATIOPEPTIDASE+NIMESULIDE is not recommended for children below 12 years of age. SERRATIOPEPTIDASE+NIMESULIDE is not recommended for pregnant women, especially in the third trimester as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking SERRATIOPEPTIDASE+NIMESULIDE. SERRATIOPEPTIDASE+NIMESULIDE should be used with caution in elderly people as it may increase the risk of severe gastrointestinal bleeding. Do not consume alcohol with SERRATIOPEPTIDASE+NIMESULIDE as it may increase the risk of stomach problems. If you develop fever or flu-like symptoms, you are advised to stop taking SERRATIOPEPTIDASE+NIMESULIDE and consult a doctor. If you have high blood pressure, fluid retention, alcoholism, drug addiction, gastrointestinal bleeding, severe heart failure, bleeding disorders, stomach ulcer, galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, severe kidney or liver problems, inform your doctor before taking SERRATIOPEPTIDASE+NIMESULIDE.
Drug Interactions
Drug-Drug Interaction: SERRATIOPEPTIDASE+NIMESULIDE may have interaction with pain killers (aspirin), antimanic agents (lithium), water pills (furosemide), blood thinners (warfarin).
Drug-Food Interaction: SERRATIOPEPTIDASE+NIMESULIDE may interact with alcohol. Therefore, avoid alcohol intake while taking SERRATIOPEPTIDASE+NIMESULIDE as it may increase the risk of stomach problems.
Drug-Disease Interaction: If you have high blood pressure, fluid retention, alcoholism, drug addiction, gastrointestinal bleeding, severe heart failure, bleeding disorders, stomach ulcer, galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, severe liver or kidney problems, inform your doctor before taking SERRATIOPEPTIDASE+NIMESULIDE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid consumption of alcohol with SERRATIOPEPTIDASE+NIMESULIDE as it may increase the risk of stomach problems.
Pregnancy
unsafeSERRATIOPEPTIDASE+NIMESULIDE is not recommended for pregnant women, especially in the third trimester as it may harm the baby. However, please consult a doctor if you are pregnant.
Breast Feeding
unsafeAvoid breastfeeding while taking SERRATIOPEPTIDASE+NIMESULIDE as it may be harmful to the baby. Please consult a doctor if you are breastfeeding.
Driving
cautionSERRATIOPEPTIDASE+NIMESULIDE may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking SERRATIOPEPTIDASE+NIMESULIDE.
Liver
cautionTake SERRATIOPEPTIDASE+NIMESULIDE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake SERRATIOPEPTIDASE+NIMESULIDE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeSERRATIOPEPTIDASE+NIMESULIDE is not recommended for children below 12 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
- Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also increase your muscle strength by lifting light weights.
- In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of chemicals called cytokines, which may increase inflammation.
- Your sitting posture is important, especially when have pain and inflammation conditions. Try to sit as little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your hips and knees at a right angle. Besides this, you can use a footrest if required.
Special Advise
Regular tests are recommended to monitor liver functioning while taking SERRATIOPEPTIDASE+NIMESULIDE.
Patients Concern
Disease/Condition Glossary
Pain can be acute (short term) or chronic (long term) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or organs. At the same time, chronic pain lasts for longer duration; it is caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. There are different types of arthritis, of which osteoarthritis and rheumatoid arthritis are the most common types. The arthritis symptoms include joint pain, redness, stiffness, tenderness, swelling in and around joints, and reduced movement of joints. The risk of arthritis increases with age, obesity, previous joint injury, or family history. Proper medication, physiotherapy, or sometimes surgery may help reduce arthritis symptoms and enhance the quality of life.
FAQs
SERRATIOPEPTIDASE+NIMESULIDE is a combination of two drugs, namely: Serratiopeptidase and Nimesulide. Serratiopeptidase is a proteolytic enzyme that helps in the breakdown of insoluble protein (fibrin, a by-product of a blood clot) into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue. Thereby, promotes healing. Nimesulide belongs to the class of non-steroidal anti-inflammatory drugs (pain relievers) that works by preventing the release of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, helps in relieving pain and swelling.
Yes, SERRATIOPEPTIDASE+NIMESULIDE may be used to treat menstrual cramps. SERRATIOPEPTIDASE+NIMESULIDE contains Nimesulide, a pain killer that decreases prostaglandins production in the body involved in making the womb contract during periods.
No, SERRATIOPEPTIDASE+NIMESULIDE does not cure arthritis. SERRATIOPEPTIDASE+NIMESULIDE is only used to relieve symptoms of arthritis such as joint pain, swelling and stiffness.
SERRATIOPEPTIDASE+NIMESULIDE should be used with caution in patients with a history of congestive heart failure as it may increase the risk of heart problems. Therefore, inform your doctor if you have any heart problems before taking SERRATIOPEPTIDASE+NIMESULIDE.
Yes, SERRATIOPEPTIDASE+NIMESULIDE may impair fertility in women. Therefore, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking SERRATIOPEPTIDASE+NIMESULIDE.
You are not recommended to take SERRATIOPEPTIDASE+NIMESULIDE with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
SERRATIOPEPTIDASE+NIMESULIDE is contraindicated in patients with active peptic ulcer disease, liver disease, kidney failure, and blood clotting disorders.
