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SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE

About

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is a combination medicine primarily used to treat burns and prevent skin infections. Burns are common household injuries that damage the skin or deeper tissues and cause the death of affected skin cells. Based on the severity of skin damage, burns are categorized into three main types: first-degree, second-degree, and third-degree burns. 

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is a combination of two drugs:  Silver sulfadiazine (nanonized) and Chlorhexidine gluconate. Silver sulfadiazine (nanonized) belongs to the class of sulfa antibiotics that inhibit the production of folic acid (a vitamin) necessary for bacteria to multiply. Thus it destroys bacteria. Chlorhexidine gluconate belongs to the antiseptics class that works by binding to the skin strongly, and it kills micro-organisms on the skin and prevents infection.

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is for external use only. Avoid contact of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with nose, ears, mouth, or eyes. In case SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE comes in contact with these areas accidentally, rinse with water thoroughly. In some cases, you may experience irritation, itching, or burning sensation at the site of application. Most of these side effects of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to any of the components in SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE, please tell your doctor. Do not swallow SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. If you are pregnant or a nursing mother, please inform your doctor before using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE. Do not apply SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE in large amounts or use it for a long time than prescribed, as it does not give quick or better results but increases the risk of side effects. Avoid contact of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with clothes or fabric as it may cause staining.

Uses of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE

Burns

Medicinal Benefits

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is a combination of two drugs, namely:  Silver sulfadiazine (nanonized) and Chlorhexidine gluconate. Silver sulfadiazine (nanonized) belongs to the class of sulfa antibiotics that works by inhibiting the production of folic acid (a vitamin) that is necessary for bacteria to multiply. Thus it destroys bacteria. Chlorhexidine gluconate belongs to the antiseptics class that works by binding to the skin strongly, and it kills micro-organisms on the skin and prevents infection.

Directions for Use

Use SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE as prescribed by your doctor. Apply a small amount of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE on the clean and dry affected area with the help of an applicator or a clean cotton ball or swab. Wash your hands before and after using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE if your hands are not the affected area to prevent the spread of infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE

  • Irritation, itching or burning sensation at the site of application

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE or any other medicines, please tell your doctor. SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is for external use only. Wear sterile disposable gloves if you are applying SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE for others, and keep the treated area clean to prevent further infection. If you are pregnant or a nursing mother, please inform your doctor before using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE. Do not apply SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE in large amounts or use it for a long time than prescribed, as it does not give quick or better results but increases the risk of side effects. Avoid contact of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with clothes or fabric as it may cause staining.  Do not swallow SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. If you have glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, or kidney or liver problems, inform your doctor before using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE.

Drug Interactions

Drug-Drug Interaction: No interactions found/established.

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: No interactions found/established.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    consult your doctor

    The interaction of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with alcohol is unknown. Please consult a doctor before consuming alcohol while using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE.

  • Safety Warning

    Pregnancy

    caution

    SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is a category B pregnancy drug and is usually not recommended for pregnant women as it may cause adverse effects in the newborn. However, please consult a doctor if you are pregnant before using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE.

  • Safety Warning

    Breast Feeding

    caution

    SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE may be excreted in human milk and cause harm to the baby. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

  • Safety Warning

    Driving

    safe if prescribed

    SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE usually does not affect your ability to drive or operate machinery.

  • Safety Warning

    Liver

    consult your doctor

    If you have any concerns regarding the use of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE in patients with liver problems, please consult a doctor.

  • Safety Warning

    Kidney

    consult your doctor

    If you have any concerns regarding the use of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE in patients with kidney problems, please consult a doctor.

  • Safety Warning

    Children

    caution

    SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE is not recommended for babies below 2 months of age as it may cause severe irritation. However, SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE should be used with caution in children above 2 months if prescribed by a doctor.

Habit Forming

No

Diet & Lifestyle Advise

  • Include protein-rich foods such as yoghurt, chicken, and eggs in your diet, as there is a loss of protein through burn wounds and the breakdown of muscles to produce extra energy for the healing process. The additional protein is required to rebuild lost muscle.
  • Add more carbohydrates to your diet, such as potatoes, beans, and rice, as glucose in carbohydrates is essential for healing.
  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach, and blueberries.
  • Drink plenty of water to stay hydrated, and avoid drinking sugary beverages.

Special Advise

  • Regular blood tests are recommended while using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE to monitor kidney functioning.
  • Please consult a dermatologist if your skin condition persists for more than 1 month.
  • Avoid contact of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with nose, ears, mouth, or eyes. In case SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE comes in contact with these areas accidentally, rinse with water thoroughly.

Patients Concern

Disease/Condition Glossary

Burns: Burns are common household injuries that damage the skin or deeper tissues and cause the death of affected skin cells. Based on the severity of skin damage, burns are categorized into three main types, namely, first-degree (also known as superficial burns, which cause minimal damage to the skin), second-degree (extends beyond the top layer of skin and causes blisters), and third-degree burns (most severe burns extending through every layer of skin).  Burns may be caused due to excessive sun exposure, electrical burns, chemical burns, hot, boiling liquids, and fires, including flames from candles, matches, or lighters.

FAQs

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE contains Silver sulfadiazine (nanonized) and Chlorhexidine gluconate. Silver sulfadiazine (nanonized) is an antibiotic that works by inhibiting the production of folic acid (a vitamin) that is necessary for bacteria to multiply. Thereby, destroys bacteria. Chlorhexidine gluconate is an antiseptic that works by binding to the skin strongly and kills micro-organisms on the skin.

Yes, SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE may cause itching of the skin at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.

You are not recommended to use SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with prilocaine (local anaesthetic) as it may increase the risk of methemoglobinemia (a blood disorder in which very less oxygen is delivered to vital organs and tissues). If you experience shortness of breath, dizziness, rapid heartbeat, anxiety, light-headedness, grey discolouration of the skin, nail bed or mouth, confusion, headache, nausea or tiredness, please consult a doctor immediately. However, consult your doctor before using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with other medicines.

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE may cause staining of clothes as it contains Chlorhexidine gluconate responsible for staining. Therefore, avoid contact of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE with clothes or fabric and also avoid bleach to wash fabric that is in contact with SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE as it may cause a permanent stain.

Please do not stop using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE without consulting your doctor, even if you find symptomatic relief. Complete the full course of SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE as your doctor has prescribed it, and if you experience any difficulty while using SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE, please consult your doctor.

Available Medicines for

SILVER SULFADIAZINE(NANONIZED)+CHLORHEXIDINE GLUCONATE

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