Sucralfate+oxetacaine
About
Sucralfate+oxetacaine belongs to a group of medicine called 'ulcer protectants' primarily used to treat peptic ulcers or gastrointestinal ulcers. It also treats hyperacidity, heartburn, indigestion, and gastritis (inflammation of the stomach). The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity and heartburn. A peptic ulcer is a sore on the stomach's lining or the first part of the small intestine (duodenum). Ulcers or sores of the stomach region are called gastric ulcers, while the duodenum ulcer is known as a duodenal ulcer.
Sucralfate+oxetacaine is a combination of two medicines: Sucralfate and Oxetacaine. Sucralfate is a gastrointestinal protectant that works by forming a protective barrier or coat over the ulcer so that digestive enzymes, acid and bile salts cannot further irritate the lining of the stomach duodenum. This protects the ulcer from the acid of the stomach, allowing it to heal. Besides this, Oxetacaine is a local anaesthetic that exerts a numbing effect, thereby providing relief from pain due to ulcers or acidic injury in the stomach.
It is better to take Sucralfate+oxetacaine an hour before a meal or without a meal for its best results. Your doctor will advise you on how often you take Sucralfate+oxetacaine based on your medical condition. Some people may experience common side effects like constipation, dizziness, sleepiness, dry mouth, blurred vision, and diarrhoea. Most of these side effects of Sucralfate+oxetacaine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Sucralfate+oxetacaine or active and inactive ingredients present on it, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Sucralfate+oxetacaine. Sucralfate+oxetacaine should not be given to children as safety has not been established. Try not to stop taking Sucralfate+oxetacaine of your own. Stopping a sudden intake of Sucralfate+oxetacaine will not influence the frequency or severity of future ulceration. Avoid taking aluminium and magnesium-containing antacids with Sucralfate+oxetacaine. Aluminium-containing antacids and Sucralfate+oxetacaine could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Avoid consuming alcohol along with Sucralfate+oxetacaine as it could lead to increased acidity.
Uses of Sucralfate+oxetacaine
Medicinal Benefits
Sucralfate+oxetacaine belongs to a group of anti-ulcerants used to treat acidity, heartburn, gas and stomach ulcers. Sucralfate+oxetacaine is a combination of two medicines: Sucralfate (anti-ulcer) and Oxetacaine (Local anaesthetic). Sucralfate works by forming a protective barrier or coat over the ulcer to pepsin and bile and inhibiting gastric acid diffusion. This protects the ulcer from the acid of the stomach, allowing it to heal. It exhibits a cytoprotective effect and forms a viscous, adhesive barrier on the intact intestinal mucosa and stomach surface. It also stimulates the synthesis and release of gastric mucosal prostaglandins and bicarbonate and the epidermal growth factor that stimulates healing and formation of new healthy skin. On the other hand, Oxetacaine exerts a numbing effect, thereby provides relief from pain due to ulcers or acidic injury in the stomach. It does not lose its activity even in strongly acidic conditions and provides prolonged anaesthetic action.
Directions for Use
Storage
Side Effects of Sucralfate+oxetacaine
- Constipation
- Dizziness
- Sleepiness
- Dry Mouth
- Nausea
In-Depth Precautions and Warning
Drug Warnings
You should avoid taking Sucralfate+oxetacaine if you are allergic to Sucralfate+oxetacaine or other ingredients present in it. Inform your doctor before taking Sucralfate+oxetacaine if you have a history of appendicitis, blockage of the bowel, rectal bleeding, kidney problems, low-magnesium diet, or if you have undergone recent bowel surgery. Caution is required before giving Sucralfate+oxetacaine to elderly patients. Sucralfate in Sucralfate+oxetacaine contains aluminium, which is normally removed by your kidney. Therefore, older adults and people who have kidney problems may be at greater risk for developing high aluminium levels while using this drug with other products that contain aluminium (e.g. antacids). Do not take Sucralfate+oxetacaine if you are pregnant or breastfeeding unless prescribed by the doctor. The safety and effectiveness in children are not established, please consult your doctor before giving them Sucralfate+oxetacaine. Avoid consuming alcohol along with Sucralfate+oxetacaine as it could lead to increased acidity.
Drug Interactions
Drug-Drug Interaction: Sucralfate+oxetacaine interact with the antacid drug (aluminium hydroxide, magnesium hydroxide), anti-HIV drug (dolutegravir), vitamin D analogs (doxercalciferol, paricalcitol), antibiotic (ciprofloxacin, gemifloxacin, levofloxacin), antidiabetic (acarbose, metformin, glipizide, glimepiride, glyburide), blood thinner (warfarin).
Drug-Food Interaction: Drinking alcohol and nicotine (tobacco) with Sucralfate+oxetacaine may cause dehydration and elevate the level of stomach acid thereby decreasing Sucralfate+oxetacaine efficacy.
Drug-Disease Interaction: Before taking Sucralfate+oxetacaine it is better to inform your doctor if you have any kidney or liver disease as a dose of Sucralfate+oxetacaine needs to be adjusted.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionDrinking alcohol with Sucralfate+oxetacaine may cause dehydration and elevate the level of stomach acid thereby decreasing Sucralfate+oxetacaine efficacy.
Pregnancy
cautionSucralfate+oxetacaine is a pregnancy category B drug. It should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast Feeding
cautionThere is limited data on how Sucralfate+oxetacaine affects breastfeeding. Please consult your doctor, before taking Sucralfate+oxetacaine. your doctor will weigh the benefits and any potential risks before prescribing it to you.
Driving
cautionSucralfate+oxetacaine decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Liver
cautionSucralfate+oxetacaine to be taken with caution if you had or have a history of liver disease/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionConsult your doctor before taking Sucralfate+oxetacaine if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Sucralfate in Sucralfate+oxetacaine contains aluminum, which is normally excreted by your kidney. Therefore, people who have kidney problems may be at greater risk for developing high aluminum toxicity in the body. The dose adjustment is necessary for patients with kidney disease.
Children
cautionThe safety and effectiveness of Sucralfate+oxetacaine in children has not been established. Please consult your doctor before giving Sucralfate+oxetacaine to children.
Habit Forming
Diet & Lifestyle Advise
- Avoid intake of acid or heartburn triggering foods or drinks like peppermint, chocolate, onions, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
- Eating five or six smaller meals throughout the day rather than three large meals. It can help reduce the production of stomach acid.
- Avoid taking alcohol and smoking cigarettes and red meat. It increases the production of stomach acid and makes symptoms worse. It can also cause erosion of the stomach lining.
- Include the high fiber-containing foods, leafy green veggies (kale, spinach), green tea in your meal. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess acid production.
- Cranberry juice can be beneficial in peptic ulcer and H. pylori infections.
Special Advise
- If your condition does not improve even after taking Sucralfate+oxetacaine for 4-5 weeks, please consult your doctor. Do not take Sucralfate+oxetacaine for more than 8 weeks.
- Sucralfate in Sucralfate+oxetacaine contains aluminium, so if you are a kidney patient, let your doctor know about this before taking Sucralfate+oxetacaine.
Patients Concern
Disease/Condition Glossary
Gastrointestinal ulcer: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste in the mouth, and difficulty swallowing. Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting. A peptic ulcer is a sore on the stomach's lining or the first part of the small intestine (duodenum). Ulcers or sores of the stomach region are called gastric ulcers, while the duodenum ulcer is known as a duodenal ulcer.
FAQs
Sucralfate+oxetacaine is a combination of two medicines: Sucralfate and Oxetacaine. Sucralfate is an antiulcers covers the damaged ulcer tissue in the stomach and protects it from acid or injury to facilitate healing. Oxetacaine is a local anesthetic that shows numbing effect provides fast relief from pain caused due to ulcers or acidic injury in the stomach.
If you miss a dose of Sucralfate+oxetacaine, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
Do not take Sucralfate+oxetacaine for longer durations unless prescribed by the doctor. Talk to your doctor if you do not feel better even after taking Sucralfate+oxetacaine for a few days.
Do not stop taking Sucralfate+oxetacaine without consulting your doctor. The stomach ulcer and duodenal ulcer tends to be recurrent disease. If you stop taking Sucralfate+oxetacaine, it will not influence the frequency or severity of future ulceration.
Do not take aspirin and ibuprofen as a pain killer while taking Sucralfate+oxetacaine unless your doctor says it to take. These pain killers increase the secretion of stomach acid and exaggerate gastrointestinal bleeding. Besides this, avoid acid-containing food/drinks, coffee, tea, carbonated drinks and vegetables like lemon, tomato etc.
