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Tamsulosin+dutasteride

About Tamsulosin+dutasteride

Tamsulosin+dutasteride is a combination drug containing 'urinary bladder relaxant' medication, used primarily in treating the enlarged prostate gland. Benign prostatic hyperplasia (enlarged prostate gland) is a non-cancerous growth of the prostate gland caused due to overproduction of a dihydrotestosterone hormone in men. As the gland enlarges, it can lead to urinary problems, such as difficulty passing urine and frequent urination. Tamsulosin+dutasteride helps in getting relief from these symptoms. And also, Tamsulosin+dutasteride does not cure prostate cancer.

Tamsulosin+dutasteride contains Tamsulosin (alpha-blockers) and Dutasteride (5-alpha reductase inhibitor), primarily used to treat enlarged prostate glands. Tamsulosin makes it easy to pass urine by relaxing the muscles of the prostate gland. On the other hand, Dutasteride reduces the enlarged prostate gland's size by lowering the production of dihydrotestosterone hormone, thereby relieving the symptoms of urinary incontinence that minimizing the need for prostate surgery and the risk of acute urinary retention. Collectively, both of them improve the symptoms of Benign Hyperplasia Prostate (BPH).

Take Tamsulosin+dutasteride as prescribed by your doctor. You are advised to take Tamsulosin+dutasteride for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Tamsulosin+dutasteride are dizziness, lightheadedness, drowsiness, sexual problems (decreased sex drive or libido), runny/stuffy nose, reduced amount of semen/sperm), testicle pain/swelling, increased breast size, or breast tenderness. They do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Women or children should not take $ name. Please inform your doctor before starting Tamsulosin+dutasteride have low blood pressure, liver/kidney disease, history of heart problems. It is advisable to wear a male contraceptive (like a condom) while having sex if your wife is pregnant as Tamsulosin+dutasteride is known to pass in semen. Do not donate blood while taking Tamsulosin+dutasteride. However, you can donate it after six months after you take the last dose of Tamsulosin+dutasteride.

Uses of Tamsulosin+dutasteride

Benign prostatic hyperplasia (BPH)

Medicinal Benefits

Tamsulosin+dutasteride contains tamsulosin (alpha-blockers) and dutasteride (5-alpha reductase inhibitor), primarily in treating the enlarged prostate gland. As the gland enlarges, it can lead to urinary problems, such as difficulty passing urine and a frequent urination urge. Dutasteride lowers the production of dihydrotestosterone hormone, which leads to a decrease in the size of the prostate and, as a result, relieves the symptoms. This will reduce the risk of acute urinary retention and the need for surgery. Tamsulosin makes it easy to pass urine by relaxing the muscles of the gland. Collectively, both of them improve the symptoms of Benign Hyperplasia Prostate (BPH).

Directions for Use

Take Tamsulosin+dutasteride with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tamsulosin+dutasteride

  • Impotence (not able to achieve or maintain an erection)
  • Decreased sex drive (libido)
  • Difficulty with ejaculation 
  • Gynecomastia (breast enlargement or tenderness)
  • Dizziness

Drug Warnings

Do not take Tamsulosin+dutasteride if you are allergic to Tamsulosin+dutasteride or any of the ingredients. Tamsulosin+dutasteride should not be taken if you have low blood pressure, which makes you feel dizzy, lightheaded or faint, glaucoma. And also, Tamsulosin+dutasteride should be taken 30 minutes after a meal. Inform your doctor if you have a history of heart disease, liver/kidney disease. Before undergoing surgery (cataract), please consult a doctor as you might be advised to stop Tamsulosin+dutasteride.  During sexual intercourse, use a condom as Tamsulosin+dutasteride is found in semen. Contact your doctor for advice if you are pregnant or plan to get pregnant before taking Tamsulosin+dutasteride as it may affect the development of male genitals. Also, keep your doctor informed about all the OTC medicines you are using while taking Tamsulosin+dutasteride. Patients taking Tamsulosin+dutasteride should be cautioned about driving, operating machinery, or performing hazardous tasks as it can cause drowsiness or dizziness. In rare cases, problems of penis erection, ejaculation, and pain in the penis can occur. So if these symptoms are for a longer time, immediately contact your doctor.

Drug Interactions

Drug-Drug Interaction: Tamsulosin+dutasteride is known to contra-indicate with medicines used to help achieve or maintain an erection (vardenafil, sildenafil, tadalafil), high blood pressure (verapamil, diltiazem), antidepressants (fluoxetine, paroxetine), anti-HIV (ritonavir, indinavir), blood thinners (warfarin), antibiotics (erythromycin), NSAIDs (diclofenac, ibuprofen, indomethacin).

Drug-Food Interaction: Tamsulosin+dutasteride is known to interact when taken along with alcohol and St John’s Wort (a natural remedy to treat depression). Also, keep your doctor informed about all the OTC medicines you are using while taking Tamsulosin+dutasteride.

Drug-Disease Interaction: Tamsulosin+dutasteride should not be given to the patients with eye problems (like glaucoma or cataract), liver/kidney disease, hypotension (low blood pressure).

Drug-Drug Interactions Checker List:

  • VARDENAFIL
  • SILDENAFIL
  • TADALAFIL
  • VERAMAPIL
  • DILTIAZEM
  • FLUOXETINE
  • PAROXETINE
  • RITONAVIR
  • INDINAVIR
  • WARFARIN
  • ERYTHROMYCIN
  • DICLOFENAC
  • IBUPROFEN
  • INDOMETHACIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Tamsulosin+dutasteride should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

    • Safety Warning

      Pregnancy

      unsafe

      As the data around the use of Tamsulosin+dutasteride in pregnant women is limited, the use of Tamsulosin+dutasteride in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      As the data around the use of Tamsulosin+dutasteride in breastfeeding women is limited, the use of Tamsulosin+dutasteride is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

    • Safety Warning

      Driving

      caution

      Tamsulosin+dutasteride can make some people feel dizzy, so it may affect your ability to drive or operate machinery safely.

    • Safety Warning

      Liver

      caution

      Tamsulosin+dutasteride should not be taken until prescribed. Regular monitoring of liver function tests is recommended.

    • Safety Warning

      Kidney

      caution

      Tamsulosin+dutasteride should not be taken until prescribed. Regular monitoring of kidney function tests is recommended.

    • Safety Warning

      Children

      unsafe

      Tamsulosin+dutasteride is not recommended for children. The safety and effectiveness of Tamsulosin+dutasteride have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid drinking less alcohol, caffeine, and fizzy drink. Limit intake of artificial sweeteners.
    • Maintain a healthy lifestyle and exercise regularly so that you do not feel heavy in the abdomen region.
    • Also, drink less water in the evening and before sleeping to have a sound sleep and do not wake up frequently for urination.
    • Any medication which may worsen urinary symptoms (medication for cold and cough) should be avoided.

    Special Advise

    • Consult your doctor immediately if you have symptoms such as shortness of breath, extreme tiredness, and swelling in your ankles and legs.
    • Tamsulosin+dutasteride is not intended for use as an antihypertensive (blood pressure lowering) drug.
    • Don't stand suddenly from a lying or resting position, which may increase the risk of falls.

    Patients Concern

    Disease/Condition Glossary

    Benign prostatic hyperplasia (BPH): Benign prostatic hyperplasia is the enlargement of the prostate gland. It is a non-cancerous growth of the prostate gland caused due to overproduction of dihydrotestosterone hormone in men. If not treated, it may lead to the formation of bladder stone, infection, and reduced kidney function. BPH usually occurs in the male who is above 50 years of age. 

    FAQs

    Tamsulosin+dutasteride contains tamsulosin (alpha-blockers) and dutasteride (5-alpha reductase inhibitor), primarily in treating the enlarged prostate gland. Dutasteride lowers the production of dihydrotestosterone hormone, which leads to a decrease in the size of the prostate and, as a result, relieves the symptoms. Tamsulosin makes it easy to pass urine by relaxing the muscles of the gland. Collectively, both of them improve the symptoms of Benign Hyperplasia Prostate (BPH).

    No, taking any cold or cough medication along with Tamsulosin+dutasteride should be avoided as it increases the urge to urinate. So, before taking any such medication, please consult your doctor.

    Tamsulosin+dutasteride is known to be harmful to men below the age of 18, childbearing women, patients with known allergy to any of the components of Tamsulosin+dutasteride.

    No, Tamsulosin+dutasteride does not cure urinary bladder cancer and should not be used for it. It just helps in relieving symptoms of the enlarged prostate gland. For better advice, you should consult your doctor.

    No, you are advised not to donate blood if you are taking Tamsulosin+dutasteride as it contains Dutasteride, which is carried in the blood and can cause congenital disabilities. Even if you stop taking Tamsulosin+dutasteride, wait for at least 6 months and consult your doctor before donating blood.

    Yes, in some cases sexual problems (like decreased sexual interest/ability/libido, ejaculation problems, decreased sperm/semen amount), testes pain/swelling, increased breast size, or breast tenderness in the male might occur. Sexual problems in a male may be continued even after stopping the intake of Tamsulosin+dutasteride. However, if any of these side effects persist, tell your doctor promptly.

    Available Medicines for

    Tamsulosin+dutasteride

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