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Tazarotene

About

Tazarotene belongs to a group of medications called ‘retinoids’ used in the treatment of psoriasis (skin forms itchy, dry patches) and acne. Psoriasis is an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen up, and itchy. It mostly affects the knee, elbows, scalp, and trunk. It is a lifelong condition, and treatment is given to remove affected skin cells and avoid flare-ups of the disease. Acne is a skin condition that is common and occurs when hair follicles are blocked with dead skin cells and oil. 

The Tazarotene contains ‘Tazarotene’ which belongs to the class of retinoids derived from vitamin A. It has anti-inflammatory and antiproliferative (decreases skin cell multiplication) properties. It works by slowing down the development of the disease. It reduces the speed of skin cell growth and blocks some substances which cause inflammation (swelling and redness) on the skin. It gradually clears the affected skin. It helps to reduce the redness, scaling, and thickness of the rashes of psoriasis.

Use Tazarotene as prescribed by your doctor. You are advised to use Tazarotene for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience dry skin, erythema (skin redness), itching, irritation, skin irritation, skin burn and skin peeling (loss of the upper layer of skin). Most of these side effects of Tazarotene do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking Tazarotene inform your doctor if you are allergic to Tazarotene or any ingredients present in it. Tazarotene should not be taken in the conditions like eczema and sunburn. Tazarotene should not be used in pregnancy as it may cause harm to the unborn baby and cause birth defects. Inform your doctor if you are breastfeeding a woman as it may not safe. Tazarotene should not be used in children below 18 years as safety and efficacy have not been established. Tazarotene has an unknown effect on the ability to drive or use machinery. So, it is better to avoid driving while using Tazarotene.

Uses of Tazarotene

Psoriasis, Acne

Medicinal Benefits

Tazarotene contains ‘Tazarotene’ that belongs to the class of ‘retinoids’. It is used to treat psoriasis. Retinoids are derived from vitamin A (retinol) and have anti-inflammatory and antiproliferative (reduces rapid skin cell division) action. Tazarotene works by slowing down the progression of the diseases. It can treat severe or extensive skin problems where the skin has become thick and scaly such as psoriasis. It is also effective for the treatment of acne. This prevents the formation of pimples, whiteheads and blackheads.

Directions for Use

Wash your hands before and after applying Tazarotene. Before using it, try to clean and dry the affected area of the skin. Applying Tazarotene to wet skin may cause skin irritation, so try not to wash the treated area. Take a small pearl-sized amount of Tazarotene on the fingertip and apply to the clean and dry affected area. Avoid contact of Tazarotene with nose, mouth, eyes, ears, or vagina. In case Tazarotene comes in contact with these areas accidentally, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tazarotene

  • Dry skin
  • Erythema (skin redness)
  • Itching
  • Irritation
  • Skin irritation
  • Skin burns
  • Skin peeling (loss of the upper layer of skin)

In-Depth Precautions and Warning

Drug Warnings

Before taking Tazarotene inform your doctor if you are allergic to Tazarotene or any ingredients present in it. If skin irritation, redness, burning, or stinging sensation worsens at the site of application, stop using Tazarotene and consult a doctor. Tazarotene should not be used for the treatment of psoriasis with increased size formation. Do not use Tazarotene on the hair. Tazarotene should not be used in the conditions like eczema, sunburn, and other skin conditions. Tazarotene should not be used if you have skin cancer. Before taking Tazarotene inform your doctor if you work outdoors. Avoid contact of Tazarotene with nose, mouth, eyes, ears, or vagina. Tazarotene should not be used in pregnancy as it may cause harm to the unborn baby and cause birth defects. Inform your doctor if you are breastfeeding a woman as it may not safe. Tazarotene should not be used in children below 18 years as safety and efficacy have not been established. Tazarotene has an unknown effect on the ability to drive or use machinery. So, it is better to avoid driving while using Tazarotene.

Drug Interactions

Drug-Drug Interaction: Tazarotene may interact with diuretics/water pills (hydrochlorothiazide), antibiotics (tetracyclines, doxycycline, ciprofloxacin, gemifloxacin, erythromycin), antipsychotics (phenothiazines), medicines for psoriasis/dandruff (coal tar, methoxsalen).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Tazarotene should be used with caution in patients with eczema, and sunburn.

Drug-Drug Interactions Checker List:

  • HYDROCHLOROTHIAZIDE
  • TETRACYCLINE
  • DOXYCYCLINE
  • CIPROFLOXACIN
  • GEMIFLOXACIN
  • ERYTHROMYCIN
  • PHENOTHIAZINE
  • METHOXSALEN
  • COAL TAR
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      The interaction of alcohol with Tazarotene is unknown. Please consult a doctor before consuming alcohol while using Tazarotene.

    • Safety Warning

      Pregnancy

      unsafe

      Tazarotene should not be used in pregnant women as it may cause harmful effects to the unborn baby or fetus and causes birth defects. Consult your doctor for further advice.

    • Safety Warning

      Breast Feeding

      unsafe

      Tazarotene may not safe during breastfeeding as it may harm the nursing baby. Consult your doctor for further advice.

    • Safety Warning

      Driving

      caution

      Tazarotene has an unknown effect on the ability to drive or use machinery. So, it is better to avoid driving while using Tazarotene.

    • Safety Warning

      Liver

      caution

      Take Tazarotene with caution, especially if you have a history of Liver diseases/conditions as it may cause side effects. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      safe if prescribed

      Tazarotene is not harmful to kidney disease. Tazarotene is safely given to kidney patients if prescribed by your doctor.

    • Safety Warning

      Children

      unsafe

      Tazarotene is not recommended for children below 18 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Use mild soap while taking baths and prefer warm baths.
    • Avoid harsh products on your skin.
    • Do not scratch or pick your skin to avoid getting the affected area infected.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
    • Avoid consumption of foods with excess sugar as it may flare up inflammation.
    • Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
    • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.
    • Avoid sun exposure while using Tazarotene as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
    • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
    • Do regular hair wash regularly and avoid hair falling across the face.
    • Use water-based cosmetic products and remove the makeup completely before going to bed.

    Special Advise

    • Do not cover the area being treated with airtight dressings like bandages unless ordered by a doctor, as this may enhance the risk of side effects.

    Patients Concern

    Disease/Condition Glossary

    Psoriasis: Psoriasis is an autoimmune skin disease characterized by red, itchy and scaly rashes. It occurs when the immune system mistakenly attacks healthy skin cells. In this condition, skin cells grow and build up rapidly resulting in scaly rashes mostly on knees, elbows, scalp and trunk. Stress and cold can act as triggers for this disease. It is a chronic disease and does not have a permanent cure. Treatment is given to control the disease and prevent flare-ups.

    Acne: Acne is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, and red, large, and tender bumps.

    FAQs

    Tazarotene is used for treating acne along with decreasing whiteheads and blackheads. It acts by reducing skin cell overgrowth and decreasing skin cell inflammation, which may cause acne.

    Yes, Tazarotene has been found to be useful for skin. It works by enhancing the thickness of the outer skin layers which helps in decreasing facial wrinkles and discoloration. It is normally helpful in patients who are using other skincare and sunlight prevention programs.

    Tazarotene contains ‘Tazarotene’ which belongs to the class of 'retinoids' and used to treat severe psoriasis and acne. It has anti-inflammatory action and reduces redness, swelling, scaling and thickness of the rashes. It also has antiproliferative properties and slows down the disease's development by reducing the speed of skin cell growth.

    Tazarotene should not be used on healthy, inflamed or eczematous skin, as it may lead to severe irritation. Externally used medicines and cosmetics that have a strong drying effect should be prevented. Weather extremes, like cold or wind, may be more irritating to patients using Tazarotene. Avoid unnecessary exposure to UV rays during the treatment. Use protective clothing and sunscreen during Tazarotene treatment.

    Tazarotene may not affect your immune system. It is not an immunosuppressant. It controls psoriasis by slowing down the progression of the disease.

    Available Medicines for

    Tazarotene

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