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Telmisartan+cilnidipine+hydrochlorothiazide

About

Telmisartan+cilnidipine+hydrochlorothiazide belongs to the class of anti-hypertensives primarily used to treat hypertension (high blood pressure) and heart-related chest pain (angina). It comprises Cilnidipine (calcium channel blocker), Telmisartan (angiotensin receptor blocker), and Hydrochlorothiazide (diuretics/'water pills). Hypertension is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease. Angina is chest pain caused by reduced blood flow to the heart.

Telmisartan+cilnidipine+hydrochlorothiazide is composed of three medicines, namely Telmisartan, Cilnidipine, and Hydrochlorothiazide. Telmisartan works by blocking the action of certain substances that are responsible for tightening the blood vessels. It allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. As a result, the blood vessels widen, and supply to the heart increases, lowering the elevated blood pressure and the workload placed on the heart.  Thus, it reduces the chance of having any heart attack or stroke in the future. Hydrochlorothiazide is a diuretic pill that works by making a person urinate more. In this way, this drug helps to get rid of excess salt and water from the body and prevents the risk of heart failure, kidney or liver disease.

Take Telmisartan+cilnidipine+hydrochlorothiazide in the same manner as suggested by your doctor. Your doctor will advise you how often you need to take Telmisartan+cilnidipine+hydrochlorothiazide based on your medical condition. Common side effects of Telmisartan+cilnidipine+hydrochlorothiazide include sore back, diarrhoea, congested feeling, spinning sensation, soreness in the sinus. Most of these side effects of Telmisartan+cilnidipine+hydrochlorothiazide do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Don't stop taking Telmisartan+cilnidipine+hydrochlorothiazide without your doctor's advice. Sudden Stopping Telmisartan+cilnidipine+hydrochlorothiazide may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms.  It is advised to drink plenty of fluids while taking this medicine to overcome dry mouth and extreme thirst. Patients suffering from kidney problems may be required to undergo regular blood creatinine, and potassium levels tests as Telmisartan+cilnidipine+hydrochlorothiazide affect electrolytes level in our body can be monitored.

Uses of Telmisartan+cilnidipine+hydrochlorothiazide

Hypertension (high blood pressure)

Medicinal Benefits

Telmisartan+cilnidipine+hydrochlorothiazide is composed of three medicines: Telmisartan, Cilnidipine and  Hydrochlorothiazide, prescribed to treat hypertension. Telmisartan works by blocking the action of certain substances that are responsible for tightening the blood vessels. It allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. As a result, the blood vessels widen, and supply to the heart increases, lowering the elevated blood pressure and the workload placed on the heart.  Thus, it reduces the chance of having any heart attack or stroke in the future. Hydrochlorothiazide is a diuretic pill that works by making a person urinate more. In this way, this drug helps to get rid of excess salt and water from the body and prevents the risk of heart failure, kidney, or liver disease. 

Directions for Use

Swallow Telmisartan+cilnidipine+hydrochlorothiazide as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Telmisartan+cilnidipine+hydrochlorothiazide

  • Sore back
  • Diarrhoea
  • Congested feeling
  • Spinning sensation
  • Soreness in the sinus

In-Depth Precautions and Warning

Drug Warnings

Telmisartan+cilnidipine+hydrochlorothiazide should be taken with caution in patients with congestive heart failure, liver disease, peripheral oedema (swelling of hands/legs), cardiogenic shock (when the heart suddenly can not pump sufficient blood), recent MI (myocardial infarction) or acute unstable angina (chest pain), severe aortic stenosis (when heart valves become diseased). You should monitor your blood pressure regularly to make sure the Telmisartan+cilnidipine+hydrochlorothiazide is working efficiently. Besides this prolonged intake of Telmisartan+cilnidipine+hydrochlorothiazide can lead to lowering of blood pressure (hypotension). So, daily monitoring of blood pressure is advisable. 

Drug Interactions

Drug-Drug Interaction: Telmisartan+cilnidipine+hydrochlorothiazide is known to interact with an anticancer drug (quinidine), antiepileptic medicine (phenytoin), anti TB drug (rifampicin), antibiotics (erythromycin), other blood pressure-lowering pills and anti-psychotic drugs, potassium-sparing diuretics or potassium supplements, lithium.

Drug-Food Interaction: Generally, no food interaction is found with this medicine. However, one should limit or avoid intake of alcoholic beverages.

Drug-Disease Interaction: Telmisartan+cilnidipine+hydrochlorothiazide is contraindicated in patients with severe aortic stenosis (narrowed heart valve), cardiogenic shock (when suddenly the heart does not get enough blood supply), a recent history of unstable angina (chest pain), heart failure, and hypotension (low blood pressure).

Drug-Drug Interactions Checker List:

  • PHENYTOIN
  • RIFAMPICIN+ISONIAZID
  • ERYTHROMYCIN
  • QUINIDINE
  • LITHIUM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Telmisartan+cilnidipine+hydrochlorothiazide can lower your blood pressure causing dizziness and drowsiness. It can also cause orthostatic hypotension (sudden fall in blood pressure while standing). So try to avoid intake of Telmisartan+cilnidipine+hydrochlorothiazide with alcoholic beverages.

    • Safety Warning

      Pregnancy

      caution

      There are no clinical data on the safety of Telmisartan+cilnidipine+hydrochlorothiazide during pregnancy. So, it should be taken with caution.

    • Safety Warning

      Breast Feeding

      caution

      The nursing mother should consult a doctor before taking Telmisartan+cilnidipine+hydrochlorothiazide.

    • Safety Warning

      Driving

      unsafe

      Telmisartan+cilnidipine+hydrochlorothiazide may cause side effects that could affect your ability to drive. Taking Telmisartan+cilnidipine+hydrochlorothiazide may lower your blood pressure

    • Safety Warning

      Liver

      caution

      There is limited information available on the use of Telmisartan+cilnidipine+hydrochlorothiazide in patients with liver disease. So Telmisartan+cilnidipine+hydrochlorothiazide should be taken with caution and with a consultation with the doctor only.

    • Safety Warning

      Kidney

      safe if prescribed

      Telmisartan+cilnidipine+hydrochlorothiazide is probably safe to use in patients with kidney disease. It has shown a beneficial and protective effect on the kidney.

    • Safety Warning

      Children

      safe if prescribed

      The safety and effectiveness of Telmisartan+cilnidipine+hydrochlorothiazide has not been established in children due to limited testing of this drug on children by competent authorities across the world. Hence, it is best to consult a child specialist.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Keep your weight under control with a BMI of 19.5-24.9.
    • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
    • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products. 
    • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
    • If you are taking alcohol, then only one serving for women and two servings for men is advisable. 
    • Quitting smoking is the best strategy to lower the risk of heart disease. 
    • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques. 
    • Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor. 
    • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help lowering your elevated blood pressure.

    Special Advise

    Sudden withdrawal may exacerbate angina (chest pain) consult your doctor immediately.

    Patients Concern

    Disease/Condition Glossary

    Blood pressure: It is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

    FAQs

    It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shoot up at any time. If you have a persistent headache, please consult your doctor immediately.

    If you miss a dose of Telmisartan+cilnidipine+hydrochlorothiazide, you are advised to take it as soon as you remember. Do not double the dose as it may lead to a lowering of blood pressure. Take one daily at the same time.

    High blood pressure in the stage of pregnancy may cause eclampsia that can be harmful to both baby and mother. So, during the pregnancy, you should have regular blood pressure monitoring.

    Telmisartan+cilnidipine+hydrochlorothiazide is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

    Yes, Telmisartan+cilnidipine+hydrochlorothiazide can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Telmisartan+cilnidipine+hydrochlorothiazide. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

    Available Medicines for

    Telmisartan+cilnidipine+hydrochlorothiazide

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