Treosulfan
About
Treosulfan belongs to the group of anti-cancer medicines called alkylating agents indicated in the treatment of advanced ovarian cancer after at least one prior standard therapy. Ovarian cancer occurs when abnormal cells grow and multiply in the ovaries and fallopian tubes.
Treosulfan contains Treosulfan, which works by inhibiting tumour growth. It prevents the cancer cells from multiplying. This helps reduce the number of cancer cells and helps treat ovarian cancer.
In some cases, Treosulfan may cause side effects such as nausea, vomiting, mild hair loss, and bronze discolouration of the skin. Most of these side effects may not require medical attention and resolve over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Consult the doctor if you are pregnant, breastfeeding, or think you may be pregnant or are planning for pregnancy. Treosulfan is not recommended for children. Inform the doctor about your health condition and medications to rule out any side effects/interactions.
Uses of Treosulfan
Medicinal Benefits
Treosulfan belongs to the group of anti-cancer medicines called bifunctional alkylating agents indicated in the treatment of advanced ovarian cancer after at least one prior standard therapy. Treosulfan contains Treosulfan, which works by inhibiting tumour growth. Thereby, it helps treat ovarian cancer.
Directions for Use
Storage
Side Effects of Treosulfan
- Nausea
- Vomiting
- Mild hair loss
- Bronze discolouration of the skin
In-Depth Precautions and Warning
Drug Warnings
Do not use Treosulfan if you are allergic to any of its components, if you have severe bone marrow depression, or if you are breastfeeding. Inform the doctor if you have lung inflammation, kidney problems or if you are undergoing any vaccination. Be cautious as Treosulfan may increase the risk of infections and blood cancers after long-term treatment. Consult the doctor if you are pregnant, think you are pregnant or planning for pregnancy. Let the doctor know if you are taking any other medicines, including supplements and herbal products.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking painkillers (ibuprofen) or anti-malarial (chloroquine).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform the doctor if you have severe bone marrow depression or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known if alcohol affects Treosulfan. Please consult your doctor.
Pregnancy
cautionTreosulfan should not be used during pregnancy unless prescribed by the doctor. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Treosulfan.
Breast Feeding
unsafeAvoid breastfeeding whilst on treatment with Treosulfan.
Driving
cautionTreosulfan may cause nausea or vomiting. Drive or operate heavy machinery only if you are alert.
Liver
consult your doctorIf you have a history of liver disease, inform your doctor before receiving Treosulfan.
Kidney
cautionIf you have a history of kidney diseases, inform your doctor before receiving Treosulfan. Dose adjustment may be needed in patients with impaired kidney function.
Children
unsafeTreosulfan is not recommended for children due to a lack of data on the safety and effectiveness.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Avoid smoking and alcohol consumption.
- Include vegetables, fruits, and whole grains in your diet.
- Avoid fast food, fried food, processed meats, refined carbs and added sugar.
- Get optimal sleep; rest well.
- Drink plenty of water or other fluids.
Special Advise
- Your doctor may advise regular blood tests to check for blood cell count.
- Women of childbearing potential must use reliable contraception during treatment with Treosulfan and for at least six months after the treatment.
- Drink more fluids than usual for up to 24 hours after your treatment.
Patients Concern
Disease/Condition Glossary
Ovarian Cancer: Ovarian cancer occurs when abnormal cells grow and multiply in the ovaries and fallopian tubes. Signs and symptoms include pain, swelling, or a feeling of pressure in the pelvis or abdomen, frequent or sudden urge to urinate, feeling full or trouble eating, a lump in the pelvic area, gas, bloating, or constipation.
FAQs
Treosulfan works by inhibiting tumour growth. Thereby, it helps treat ovarian cancer.
Treosulfan may cause mild hair loss. The hair may grow back after the treatment with Treosulfan. However, consult your doctor if you have any concerns.
The risk of generalised infection may be increased after some vaccinations. Therefore, do not receive any live vaccinations during therapy.
