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Trypsin+bromelain+rutoside

About

Trypsin+bromelain+rutoside is a combination medication that belongs to a class of medication called 'analgesic' used to relieve musculoskeletal pain in the conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time (acute) or long time (chronic).  

Trypsin+bromelain+rutoside is a combination of one antioxidant (Rutoside) and two enzymes (Trypsin and Bromelain). Rutoside is an antioxidant that prevents cell damage, reduces toxins, protects the body from damage caused by free radicals (toxins), and decreases swelling. Trypsin removes dead skin cells and allows the growth of healthy tissue. On the other hand, Bromelain is a pineapple extract limiting fibrin formation by reducing clots or plaque at the damaged/injured site. Together it reduces swelling and inflammation by producing substances in the body against pain and swelling. Thus, Trypsin+bromelain+rutoside helps in relieving edema (fluid overload), inflammation and promotes wound healing. 

Take Trypsin+bromelain+rutoside with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience vomiting, nausea, diarrhea, rash, or mouth sores. Most of these side effects of Trypsin+bromelain+rutoside do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Trypsin+bromelain+rutoside or any other medicines, please tell your doctor. Avoid Trypsin+bromelain+rutoside in patients who are allergic to pineapple, carrot, papaya, fennel, and pollens. Trypsin+bromelain+rutoside is not recommended for pregnant women as it contains Bromelain, which may cause abortion or miscarriage. If you are pregnant or planning for pregnancy, please consult a doctor before taking Trypsin+bromelain+rutoside. Before undergoing any planned surgery, inform your doctor that you are taking Trypsin+bromelain+rutoside. It should be stopped a minimum of 2 weeks before surgery due to increased bleeding risk during and after surgery. If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), kidney or liver disorders, inform your doctor before taking Trypsin+bromelain+rutoside.

Uses of Trypsin+bromelain+rutoside

Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis

Medicinal Benefits

Trypsin+bromelain+rutoside is a combination of one antioxidant (Rutoside) and two enzymes (Trypsin, Bromelain). Rutoside is an antioxidant (substances that prevent damage to cells) that works by protecting the body from damage caused by free radicals (unstable molecules produced by the body) and further decreases swelling. Trypsin removes dead skin cells and allows the growth of healthy tissue. In combination with Bromelain, Trypsin reduces swelling and inflammation by producing substances in the body against pain and swelling in the conditions of joint disorders like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.  

Directions for Use

Take Trypsin+bromelain+rutoside with or without food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trypsin+bromelain+rutoside

  • Vomiting
  • Nausea
  • Diarrhea
  • Rash
  • Mouth sores
  • Gastrointestinal discomfort

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Trypsin+bromelain+rutoside or any other medicines, please tell your doctor. People allergic to pineapple, carrot, papain, fennel, and pollen should avoid the intake of Trypsin+bromelain+rutoside. It is not recommended for pregnant women as it contains Bromelain, which may cause miscarriage, so if you are pregnant or planning for pregnancy, let your doctor know about this. If you are about to undergo any surgery, inform your doctor that you are taking Trypsin+bromelain+rutoside. It should be stopped a minimum of 2 weeks before surgery as Trypsin+bromelain+rutoside may increase the risk of bleeding during and after surgery. If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), kidney or liver disorders, inform your doctor before taking Trypsin+bromelain+rutoside.

Drug Interactions

Drug-Drug Interaction: Trypsin+bromelain+rutoside may have interaction with painkillers (aspirin, diclofenac, ibuprofen, naproxen), blood thinners (warfarin, clopidogrel, dalteparin, enoxaparin, heparin), antibiotics (amoxicillin, demeclocycline, minocycline, tetracycline), drugs used to dissolve blood clots (alteplase, reteplase, streptokinase), high blood pressure-lowering medicines (captopril, enalapril, fosinopril, lisinopril).

Drug-Food Interaction: Trypsin+bromelain+rutoside may interact with ginger, garlic, asafoetida, alfalfa, arnica, fenugreek, potato, soybean, licorice, red clover, celery, angelica, meadowsweet, quassia, willow,  chestnut, chamomile, and clover.

Drug-Disease Interaction: If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), kidney or liver disorders, inform your doctor before taking Trypsin+bromelain+rutoside.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • DICLOFENAC
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN
  • CLOPIDOGREL
  • DALTEPARIN
  • ENOXAPARIN
  • HEPARIN
  • AMOXICILLIN
  • DEMECLOCYCLINE
  • MINOCYCLINE
  • TETRACYCLINE
  • ALTEPLASE
  • RETEPLASE
  • STREPTOKINASE
  • CAPTOPRIL
  • ENALAPRIL
  • FOSINOPRIL
  • LISINOPRIL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      The interaction of alcohol with Trypsin+bromelain+rutoside is unknown. Please consult a doctor before consuming alcohol with Trypsin+bromelain+rutoside.

    • Safety Warning

      Pregnancy

      unsafe

      Trypsin+bromelain+rutoside is usually not recommended for pregnant women as it may cause miscarriage. However, please consult a doctor if you are pregnant or planning for pregnancy.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Trypsin+bromelain+rutoside is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Trypsin+bromelain+rutoside is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      caution

      Avoid driving if you experience any symptoms which may affect your ability to react or concentrate after taking Trypsin+bromelain+rutoside.

    • Safety Warning

      Liver

      caution

      Take Trypsin+bromelain+rutoside with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Trypsin+bromelain+rutoside with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Trypsin+bromelain+rutoside is not recommended for children until and unless prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
    • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also increase your muscle strength by lifting light weights.
    • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
    • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of chemicals called cytokines, which may increase inflammation.
    • Your sitting posture is important, especially when have pain and inflammation condition. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your hips and knees at a right angle. Besides this, you can use a footrest if required.

    Special Advise

    Trypsin+bromelain+rutoside must not be used by patients with severe inborn bleeding disorders like hemophilia, severe liver damage, and dialyzed patients. 

    Patients Concern

    Disease/Condition Glossary

    Osteoarthritis and rheumatoid arthritis: It is a chronic condition caused due to wear and tear on the joints with sore/stiff joints, and pain worsens after activity or the end of the day. In rheumatoid arthritis, the immune system attacks musculoskeletal joints and other body parts with pain, fatigue, swollen, warm, and inflamed-looking joints. Arthritis cannot be cured but can be managed. 

    FAQs

    Trypsin+bromelain+rutoside is a combination of one antioxidant (Rutoside) and two enzymes (Trypsin, Bromelain). Rutoside is an antioxidant (substances that prevent damage to cells) that works by protecting the body from damage caused by free radicals (unstable molecules produced by the body) and further decreases swelling. Trypsin removes dead skin cells and allows the growth of healthy tissue. Trypsin in combination with Bromelain reduces swelling and inflammation by producing substances in the body against pain and swelling.

    Yes, Trypsin+bromelain+rutoside may be used to treat menstrual cramps. Trypsin+bromelain+rutoside is a pain killer that produces substances in the body against pain and swelling.

    You are not recommended to take Trypsin+bromelain+rutoside with warfarin as co-administration of these two medicines may slow down blood clotting and increase the risk of bleeding more easily. However, please consult a doctor before using Trypsin+bromelain+rutoside with other medicines.

    You may have to stop taking Trypsin+bromelain+rutoside minimum 2 weeks before surgery as Trypsin+bromelain+rutoside may increase the risk of bleeding during and after surgery. However, if you are about to undergo any surgery, inform your doctor that you are taking Trypsin+bromelain+rutoside.

    Arthritis is a non-curable disease but can be managed. Trypsin+bromelain+rutoside does not cure arthritis but can relieve symptoms of arthritis-like joint pain and swelling.

    Available Medicines for

    Trypsin+bromelain+rutoside

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