VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE
About
VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE is a combination drug that belongs to the antidiabetic class. It is primarily used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.
VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE contains Voglibose, Repaglinide, and Metformin Hydrochloride. Voglibose inhibits the enzymes in the intestine that break down complex carbohydrates into simple sugars like glucose, slowing glucose absorption. Repaglinide stimulates the pancreas to secrete insulin and helps manage the amount of glucose (sugar) in the blood by increasing the amount of insulin generated by the pancreas. Metformin decreases glucose synthesis in the liver, slows glucose absorption in the intestines, and boosts insulin sensitivity. They collaborate to maintain blood glucose levels that are consistent throughout the day.
VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE is a prescription-only medication. You can take VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. The dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsen (if your blood sugar is too high or too low). In some cases, you may experience common side effects, such as Hypoglycaemia, Allergy/ Skin Reactions, Stomach Pain, Diarrhoea, Abdominal Pain, Heartburn, Nausea, and Vomiting. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not use VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE without a doctor's advice if you had a skin reaction or irritation to any medicine. VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should not be stopped even if you feel better without consulting your doctor as the sugar level keeps changing. If you stop taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. During pregnancy/lactation, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Keep your doctor informed about your health condition and all the medicines you take before taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE to rule out any side effects/interactions. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness. VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE is not recommended in children below 18 years of age.
Uses of VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE
Medicinal Benefits
VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE contains Voglibose, Repaglinide, and Metformin Hydrochloride. Voglibose inhibits the enzymes in the intestine that break down complex carbohydrates into simple sugars like glucose, slowing glucose absorption. Repaglinide stimulates the pancreas to secrete insulin and helps manage the amount of glucose (sugar) in the blood by increasing the amount of insulin produced by the pancreas. Metformin works by decreasing glucose synthesis in the liver, slowing glucose absorption in the intestines, and increasing insulin sensitivity. They work together to keep blood glucose levels consistent throughout the day.
Directions for Use
Storage
Side Effects of VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE
- Low blood sugar (hypoglycaemia)
- Upper respiratory infection
- Flu-like symptoms
- Back pain
- Joint pain
- Dizziness
- Skin rash or allergic reactions on the skin
- Indigestion or delayed digestion
- Loss of appetite
- Stomach ache or stomach upset
- Diarrhoea
- Blurred vision
- Feeling of restlessness
- Feeling restless
- Weakness or fatigue
In-Depth Precautions and Warning
Drug Warnings
Before taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE, tell your doctor or healthcare professional if you are allergic to Repaglinide, Voglibose, Metformin Hydrochloride, or if you have any other allergies. This product may contain inactive ingredients that can cause allergic reactions or other issues. VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should not be stopped without consulting your doctor, even if you feel better. If you stop taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE abruptly, your blood sugar levels may rise, increasing your risk of vision loss (retinopathy), kidney damage (nephropathy), and nerve damage (neuropathy). If you have type 1 diabetes or severe kidney or liver disease, you should not take the VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE. Consult your doctor about the risks and benefits if you are pregnant/lactation, as this medication should be used only when clearly necessary during pregnancy/lactation. You may experience blurred vision, dizziness, or drowsiness due to low or high blood sugar levels. Do not drive, operate machinery, or engage in any activity that requires alertness or clear vision until you are confident in your ability to do so safely. Limit or avoid alcohol consumption while using this medication because it increases your chances of developing low blood sugar and a high ketone level. Keep your doctor informed about your health condition and all medications you take to rule out any negative effects/interactions.
Drug Interactions
Drug-Drug Interactions: VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE may interact with certain diuretic medications (e.g. acetazolamide), certain medicines used to treat recurrent urinary tract infections (e.g. cinoxacin, nalidixic acid), certain antibiotics (e.g. ciprofloxacin, delafloxacin, moxifloxacin, gatifloxacin), certain antiplatelet medications (e.g. clopidogrel), certain immunosuppressant's (e.g. cyclosporine), certain medicines used to treat acute angle-closure glaucoma (e.g. dichlorphenamide, methazolamide), certain diagnostic agents (e.g. diatrizoate, iodamide, iodipamide, iodixanol), certain lipid-regulating medications (e.g. gemfibrozil), and certain anticonvulsants (e.g. topiramate, zonisamide),
Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE.
Drug-Disease Interactions: VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE may interact with disease conditions, including type I diabetes, lactic acidosis, cardiovascular risk, hypoglycaemia, B12 deficiency, liver disease, and renal impairment.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionLimit or avoid consumption of alcohol while taking this medication because it can increase your risk of developing low blood sugar and a high ketone level.
Pregnancy
cautionVOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should be used only if clearly needed during pregnancy. If you are pregnant, consult your doctor before taking this medicine. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
cautionIf you are breastfeeding, please consult your doctor before taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
cautionDue to extremely low or high blood sugar levels, you may experience blurred vision, dizziness, or drowsiness. Do not drive, operate machinery, or engage in any activity that requires alertness or clear vision until you are confident that you can do so safely.
Liver
cautionVOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should be used with caution, particularly if you have a pre-existing liver problem or a history of liver disease. Please consult your doctor. Your doctor may adjust the dose of VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE or prescribe a suitable alternative.
Kidney
cautionVOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should be used with caution, particularly if you have a pre-existing or a history of Kidney diseases/conditions. Your doctor may need to adjust the dose based on your renal function. In the case of severe kidney disease, VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE is not advised. If you're taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE, you should have your kidney function tests checked regularly. Please consult your doctor before taking any medication. Before prescribing VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE, your doctor will consider the benefits and potential risks.
Children
unsafeThe safety and efficacy of VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE in children have not been established. Please consult your doctor if you have any concerns regarding this.
Habit Forming
Diet & Lifestyle Advise
- Every week, devote at least 150 minutes to moderate-intensity physical activity or one hour and 15 minutes to high-intensity exercise.
- Losing weight gradually to achieve a healthy BMI (18.5 to 24.9).
- Replace refined carbohydrates with whole grain foods and increase intake of fruits and vegetables and other fibre-rich foods.
- Reduce your consumption of saturated fat (or hidden fats) in foods such as chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-rich oils for everyday cooking.
- Avoid excessive stress because it can raise your blood sugar level. You can control stress-related blood sugar changes using stress management techniques such as mindfulness, meditation, or yoga.
- Choose low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
- Maintaining a normal blood pressure (120/80) as much as possible reduces the risk of cardiovascular disease in people with diabetes.
Special Advise
- Continue to take VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE even if you believe your blood sugar levels are under control.
- If you miss a dose, do not double the dose. Seek advice from your treating physician.
- When taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE, eat small, frequent meals and avoid fasting for long periods. Be aware of hypoglycemia (low blood sugar) symptoms such as sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, and so on. If you experience any of the above symptoms, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and contact your doctor. Carry these with you at all times, especially during long journeys.
- Before your doctor prescribes VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE, make sure your doctor is aware of any underlying conditions such as kidney or liver disease, a previous heart attack, alcohol consumption, and so on.
- While on VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE, avoid drinking alcohol. It raises the risk of hypoglycemia (low blood sugar, which can be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, impacting the functioning of various organs in the body).
- Quit smoking and limit your intake of carbohydrate-rich foods such as potatoes, rice, mangoes, bread, sugar, and so on.
- Remember that lifestyle changes are the most important step in controlling blood sugar levels.
Patients Concern
Disease/Condition Glossary
Type 2 diabetes is a chronic or lifelong disease that keeps the body away from properly utilizing insulin. Hence, people with type 2 diabetes either do not produce enough insulin or resist insulin action. Middle-aged or older are most likely to suffer from type 2 diabetes, also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while weight loss may be observed in rare cases. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increase in the chance of heart attack or stroke.
FAQs
VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE comprises three drugs: Voglibose, Repaglinide, and Metformin Hydrochloride. Voglibose inhibits the enzymes in the intestine that break down complex carbohydrates into simple sugars like glucose, slowing glucose absorption. Repaglinide stimulates the pancreas to secrete insulin and helps manage the amount of glucose (sugar) in the blood by increasing the amount of insulin produced by the pancreas. Metformin works by decreasing glucose synthesis in the liver, slowing glucose absorption in the intestines, and increasing insulin sensitivity. They work together to keep blood glucose levels consistent throughout the day.
If you have increased hunger, thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact the doctor as it can be a condition of type 2 diabetes.
No. VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE is only prescribed to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.
VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE should be avoided in patients allergic to any of the components or excipients of this medicine. It should be avoided in patients with moderate to severe kidney or liver disease. Using this drug is also not advised if you drink too much alcohol. Make sure to inform your healthcare professional if you are pregnant or breastfeeding.
There is no evidence that VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE reduces fertility in either men or women.
Please do not stop taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE without consulting your doctor on your own, as it may cause an increase in blood glucose levels. Continue taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE for as long as your doctor prescribes it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking VOGLIBOSE+REPAGLINIDE+METFORMIN HYDROCHLORIDE.
You can make lifestyle changes to help control the symptoms of type 2 diabetes. Remember, lifestyle modifications are the most important step in controlling blood sugar levels.
