apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition

LEFLUNOMIDE-20MG

Manufacturer/Marketer

Medieos Life Sciences Llp

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Rhumieos-20 Tablet

Rhumieos-20 Tablet belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Rhumieos-20 Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Rhumieos-20 Tablet at the same time every day as prescribed by your doctor. In some cases, Rhumieos-20 Tablet may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Rhumieos-20 Tablet if you are pregnant or planning for pregnancy as Rhumieos-20 Tablet may cause serious congenital disabilities. Rhumieos-20 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Rhumieos-20 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol along with Rhumieos-20 Tablet as it could lead to increased dizziness and liver damage. Rhumieos-20 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Uses of Rhumieos-20 Tablet

Rheumatoid arthritis, Psoriatic arthritis

Directions for Use

Take Rhumieos-20 Tablet with or without food. Swallow Rhumieos-20 Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Rhumieos-20 Tablet belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rhumieos-20 Tablet is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rhumieos-20 Tablet

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Drug Warnings

Do not take Rhumieos-20 Tablet if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Rhumieos-20 Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Rhumieos-20 Tablet if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Rhumieos-20 Tablet may cause dizziness, so drive with caution. Rhumieos-20 Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug-Drug Interactions

verifiedApollotooltip
LeflunomideLevamisole
Severe
LeflunomideSorafenib
Severe

Drug-Drug Interactions

Login/Sign Up

LeflunomideLevamisole
Severe
How does the drug interact with Rhumieos-20 Tablet:
When cladribine and levamisole are used together, there is a higher chance of getting serious infections.

How to manage the interaction:
There may be a possibility of interaction between Levamisole and Rhumieos-20 Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms - infection, complications, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not stop using any medications without a doctor's advice.
LeflunomideSorafenib
Severe
How does the drug interact with Rhumieos-20 Tablet:
Coadministration of Rhumieos-20 Tablet with sorafenib can increase the risk of liver problems.

How to manage the interaction:
Taking Sorafenib with Rhumieos-20 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LeflunomideInfliximab
Severe
How does the drug interact with Rhumieos-20 Tablet:
Combining Infliximab with Rhumieos-20 Tablet can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Rhumieos-20 Tablet with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, burning, paleness, fatigue, dizziness, lightheadedness, and bruising or bleeding when you pee, contact a doctor right away. Do not discontinue any medications without first consulting a doctor.
LeflunomideCaspofungin
Severe
How does the drug interact with Rhumieos-20 Tablet:
Rhumieos-20 Tablet can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Rhumieos-20 Tablet and Caspofungin, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
LeflunomideSodium Valproate
Severe
How does the drug interact with Rhumieos-20 Tablet:
Co-administration of Rhumieos-20 Tablet and sodium valproate can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Rhumieos-20 Tablet and sodium valproate can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LeflunomideIsoniazid
Severe
How does the drug interact with Rhumieos-20 Tablet:
Taking Isoniazid with Rhumieos-20 Tablet can increase the risk and severity of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Rhumieos-20 Tablet and Isoniazid, it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash, itching, exhaustion, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
LeflunomideMinocycline
Severe
How does the drug interact with Rhumieos-20 Tablet:
Co-administration of Rhumieos-20 Tablet with minocycline can increase the risk or severity of liver disorder.

How to manage the interaction:
Although taking Rhumieos-20 Tablet and minocycline together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
LeflunomideBrigatinib
Severe
How does the drug interact with Rhumieos-20 Tablet:
Brigatinib can cause higher levels of Rhumieos-20 Tablet in the blood by reducing its excretion.

How to manage the interaction:
There may be a possibility of interaction between Rhumieos-20 Tablet and Brigatinib, but it can be taken if prescribed by a doctor. If you notice symptoms like fever, chills, sore throat, or muscle aches, contact your doctor immediately. Other symptoms to look out for include diarrhea, shortness of breath, weight loss, and pain or burning while urinating." Do not discontinue any medications without consulting your doctor.
LeflunomideMoxifloxacin
Severe
How does the drug interact with Rhumieos-20 Tablet:
Taking Moxifloxacin and Rhumieos-20 Tablet may increase the risk of liver problems.

How to manage the interaction:
Co-administration of Rhumieos-20 Tablet with Moxifloxacin can result in an interaction, but it can be taken if a doctor has advised it. If you experience fever, joint pain or swelling, vomiting, abdominal pain, dark colored urine, or yellowing of the skin or eyes contact a doctor right away. Do not discontinue any medications without consulting a doctor.
LeflunomidePosaconazole
Severe
How does the drug interact with Rhumieos-20 Tablet:
Taking Rhumieos-20 Tablet with posaconazole can increase the risk of liver problems.

How to manage the interaction:
Although using Posaconazole and Rhumieos-20 Tablet together can result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIRHEUMATICS

Rhumieos-20 Tablet Substitute

Substitutes safety advice
  • Lefno-20 Tablet 10's

    by Others

    25.83per tablet
  • Lefra 20 Tablet 10's

    by Others

    26.37per tablet
  • Rumalef 20 Tablet 30's

    by Others

    17.90per tablet
  • Cleft 20 Tablet 10's

    by Others

    21.83per tablet
  • Lefumide-20 Tablet 10's

    by Others

    24.03per tablet

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Special Advise

Regular blood tests to monitor your liver function after starting Rhumieos-20 Tablet , and for every 6-8 weeks are advised.

Disease/Condition Glossary

Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness. 

Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

whatsapp Floating Button