Azithromycin+fluconazole+secnidazole
About
Azithromycin+fluconazole+secnidazole belongs to the class of 'antibiotics', primarily used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). Trichomoniasis is a sexually transmitted infection caused by a parasite. Chlamydia is a sexually transmitted infection caused by bacteria. Symptoms of a vaginal infection include itching, odour and abnormal vaginal discharge.
Azithromycin+fluconazole+secnidazole comprises three medicines: Azithromycin (antibiotic), Fluconazole (antifungal), and Secnidazole (antibiotic). Azithromycin belongs to the class of 'macrolide antibiotics'. It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. Fluconazole belongs to the class of 'azole antifungal' agents. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic that belongs to the class of 'amoebicides'. It works by stopping the growth of infection-causing bacteria.
Use Azithromycin+fluconazole+secnidazole as prescribed by the doctor. Common side effects of Azithromycin+fluconazole+secnidazole include taste changes, vomiting, headache, dizziness, stomach pain, nausea, indigestion, diarrhoea, and loss of appetite. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Inform your doctor if you are allergic to Azithromycin+fluconazole+secnidazole or any of its components. It is essential to tell your doctor if you use any other azole antifungal agents before using Azithromycin+fluconazole+secnidazole. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Pregnant and breastfeeding women should consult their doctor before starting Azithromycin+fluconazole+secnidazole. It is advised to avoid alcohol intake while using Azithromycin+fluconazole+secnidazole to prevent any undesirable effects.
Uses of Azithromycin+fluconazole+secnidazole
Medicinal Benefits
Azithromycin+fluconazole+secnidazole is used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. It comprises three medicines: Azithromycin, Fluconazole, and Secnidazole. Azithromycin is an antibiotic that works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth. Fluconazole is an antifungal drug that stops fungi growth by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic works by stopping the growth of infection-causing bacteria. It effectively treats vaginal infection (bacterial vaginosis).
Directions for Use
Storage
Side Effects of Azithromycin+fluconazole+secnidazole
- Taste changes
- Vomiting
- Headache
- Dizziness
- Stomach pain
- Nausea
- Indigestion
- Diarrhoea
- Loss of appetite
In-Depth Precautions and Warning
Drug Warnings
Please inform your doctor if you use any prescription, non-prescription medicines, including vitamin and herbal supplements before using Azithromycin+fluconazole+secnidazole. Do not use Azithromycin+fluconazole+secnidazole if you are allergic to Azithromycin+fluconazole+secnidazole or any of its components. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Azithromycin+fluconazole+secnidazole is not recommended in case of severe renal impairment. It is advised to use Azithromycin+fluconazole+secnidazole under your doctor's supervision if you use other azole antifungal medicines. It is better to avoid Azithromycin+fluconazole+secnidazole during the first trimester of pregnancy. Azithromycin+fluconazole+secnidazole should be used with caution and only under a doctor's advice if you are a nursing mother. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Azithromycin+fluconazole+secnidazole to avoid undesirable effects like flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. Do not take any antacids containing magnesium or aluminum for up to two hours after using Azithromycin+fluconazole+secnidazole.
Drug Interactions
Drug-Drug Interaction: Azithromycin+fluconazole+secnidazole may interact with magnesium or aluminium-containing antacids, heart-related medicines (digoxin), insomnia-treating drugs (triazolam), immunosuppressants (cyclosporine, tacrolimus), fits medicines (carbamazepine, phenytoin), antibiotics (rifampicin, rifabutin), respiratory drugs (theophylline), anti-allergy drugs (astemizole), and blood thinners.
Drug-Food Interaction: Avoid alcohol intake while using Azithromycin+fluconazole+secnidazole.
Drug-Disease Interaction: Before taking Azithromycin+fluconazole+secnidazole, let your doctor know if have any liver, kidney, gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAlcohol consumption, along with Azithromycin+fluconazole+secnidazole, may cause flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. It is advised to avoid alcohol intake during the course with Azithromycin+fluconazole+secnidazole.
Pregnancy
cautionIt is better to avoid Azithromycin+fluconazole+secnidazole during the first trimester of pregnancy. Please consult your doctor if you are planning to conceive or already pregnant before starting Azithromycin+fluconazole+secnidazole.
Breast Feeding
cautionAzithromycin+fluconazole+secnidazole should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.
Driving
cautionAzithromycin+fluconazole+secnidazole may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are nor mentally alert.
Liver
cautionLet your doctor know if you have any history of liver diseases before taking Azithromycin+fluconazole+secnidazole. Your doctor may adjust the dosage.
Kidney
cautionCaution is recommended if you have any history of kidney diseases before taking Azithromycin+fluconazole+secnidazole. Your doctor may adjust the dosage. Azithromycin+fluconazole+secnidazole is not recommended in case of severe renal impairment.
Children
unsafeAzithromycin+fluconazole+secnidazole is not recommended for children below 12 years of age. Do not give this medicine to your child without medical advice.
Habit Forming
Diet & Lifestyle Advise
- Avoid frequent douching to maintain the natural moisture in the vagina.
- Use mild soap while taking baths and prefer warm baths.
- Avoid harsh products on your skin.
- Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
- Avoid or limit the intake of alcohol and caffeine.
Special Advise
It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment.
Patients Concern
Disease/Condition Glossary
Bacterial vaginosis: It is a type of vaginal infection caused by the change in the normal balance of vaginal bacteria.
Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva).
Trichomoniasis is a sexually transmitted infection caused by a parasite. Symptoms of a vaginal infection include itching, odor, and abnormal vaginal discharge.
FAQs
Azithromycin+fluconazole+secnidazole consists of three antibiotic drugs, namely Azithromycin, Fluconazole, and Secnidazole. These are effective against various infection-causing microbes by inhibiting their growth. Thus Azithromycin+fluconazole+secnidazole helps to treat a variety of vaginal infections.
Azithromycin+fluconazole+secnidazole should be used with proper caution and doctor consultation if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), active infections, allergic conditions, ulcers or blisters, and urination problems.
Do not stop using Azithromycin+fluconazole+secnidazole even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.
It is not advised to take any antacids containing magnesium or aluminium for up to two hours after using Azithromycin+fluconazole+secnidazole since it may interfere with the absorption of Azithromycin+fluconazole+secnidazole.
Keep Azithromycin+fluconazole+secnidazole in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
