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Buserelin

About

Buserelin belongs to the group of medicines called gonadotropin-releasing hormone analogues indicated in the treatment of prostate cancer in men who have not had testicles removed by surgery. Prostate cancer is a cancer that occurs in the man’s prostate gland.

Buserelin contains Buserelin, a hormone therapy drug which works by reducing the production of testosterone and helps to stop the growth of cancer cells.

In some cases, Buserelin may cause side effects such as nausea, vomiting, abdominal pain, headache, diarrhoea, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, if any of the side effects persist or worsen, consult your doctor.

Let the doctor know if you are allergic to any of the components in Buserelin. Buserelin is not intended for use in women. Inform your doctor about your health condition and medications to rule out any side effects/interactions. It is critical not to father a kid while on this medication and for several months thereafter. This medication has the potential to harm a baby growing in the womb. Before beginning therapy, consult with your healthcare professional about effective contraception. While using this medication, you may have dizziness, drowsiness, or blurred vision. If this occurs, do not drive or operate any tools or machinery.

Uses of Buserelin

Prostate cancer

Medicinal Benefits

Buserelin belongs to the group of medicines called gonadotropin-releasing hormone analogues indicated in the treatment of prostate cancer who have not had testicles removed by surgery. Buserelin contains Buserelin, a type of hormone therapy known as a luteinising hormone blocker. It works by preventing the pituitary gland from releasing luteinising hormone. This prevents the testicles from producing testosterone, which is required by the prostate gland to grow. By reducing testosterone, Buserelin shrinks and prevents the growth of prostate cancer.

Directions for Use

Buserelin will administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Buserelin

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Abdominal pain
  • Feeling dizzy, sleepy, or tired
  • Headache

In-Depth Precautions and Warning

Drug Warnings

Do not take Buserelin if you are allergic to any of its components or if you have had an operation to remove testicles. Inform the doctor if you have depression, high blood pressure, diabetes, heart problems, or bone disease such as osteoporosis. Consult the doctor if you notice signs of infections like fever, mouth ulcers or sore throat, if you bleed or bruise more easily, have a severe headache or eyesight problems, have changes in blood pressure, or have problems passing urine.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking drugs used to treat heart rhythm problems (quinidine, disopyramide, amiodarone, sotalol), pain killers (methadone), antibiotic (moxifloxacin), and antipsychotics (risperidone).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have depression, high blood pressure, diabetes, heart problems, or bone disease such as osteoporosis.

Drug-Drug Interactions Checker List:

  • QUINIDINE
  • DISOPYRAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      It is not known whether Buserelin interacts with alcohol. Please consult your doctor.

    • Safety Warning

      Pregnancy

      not applicable

      -

    • Safety Warning

      Breast Feeding

      not applicable

      -

    • Safety Warning

      Driving

      caution

      In some cases, Buserelin may cause dizziness or sleepiness. Drive or operate machinery only if you are alert and have clear vision.

    • Safety Warning

      Liver

      consult your doctor

      Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Buserelin in patients with liver impairment.

    • Safety Warning

      Kidney

      consult your doctor

      Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Buserelin in patients with kidney impairment.

    • Safety Warning

      Children

      consult your doctor

      Limited information is available. Please consult the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • After your treatment begins, several dietary adjustments can help you control side effects.
    • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
    • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
    • Eat a healthy diet and exercise regularly to maintain proper weight.
    • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
    • Performing yoga may also help in improving both physical and mental health.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get optimal sleep; rest well.
    • Avoid smoking and alcohol consumption.
    • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

    Special Advise

    • The doctor may advise regular blood tests before and during the treatment to check the levels of testosterone, blood levels, and liver/kidney functioning.
    • Buserelin might change the level of liver enzymes and fats in the blood (lipids) shown up in blood tests. Therefore, if you are undergoing any tests, inform the doctor that you are on treatment with Buserelin.
    • Regular monitoring of blood pressure and blood glucose levels is advised.
    • Use effective contraception and avoid fathering a child during treatment with Buserelin and for a few months afterwards.

    Patients Concern

    Disease/Condition Glossary

    Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning sensation during urination.

    FAQs

    Buserelin works by reducing the production of testosterone, thereby preventing the growth of prostate cancer.

    Buserelin may cause muscle or bone pain, including pain in the back or jaw. Consult your doctor if you experience muscle or bone pain; the doctor may prescribe painkillers.

    Do not father a child during treatment with Buserelin and for a few months afterwards, as it might harm the developing baby in the womb. Discuss with your doctor regarding effective contraception.

    Buserelin might affect blood sugar levels. You may need to check your blood glucose levels more regularly if you have diabetes.

    Extreme caution should be applied. There have been reports of significant depression among patients who take Buserelin. If you need to use Buserelin, and you have had depression, you may be prone to severe depression; if it happens, contact your doctor right away.

    Available Medicines for

    Buserelin

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