Doxycycline+tinidazole
About
Doxycycline+tinidazole belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, vagina, skin, blood, nose, throat, gums, chest, and lungs. Also, Doxycycline+tinidazole may be used to treat infections such as giardiasis and amoebiasis (stomach infections), and trichomoniasis (genital infection) caused by protozoa. A bacterial infection is a condition in which harmful bacteria grows in the body and cause infection. It can infect any part of the body and multiple very quickly. Doxycycline+tinidazole does not work against infections caused by the virus.
Doxycycline+tinidazole is a combination of two antibiotics, namely: Doxycycline and Tinidazole. Doxycycline works by inhibiting the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Tinidazole works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA essential for bacteria's survival. Thereby, it kills micro-organisms and prevents the spread of infection.
You are advised to take Doxycycline+tinidazole for as long as your doctor has prescribed it for you based on your medical condition. You may experience vomiting, nausea, diarrhoea, stomach pain or cramps, headache, or loss of appetite in some cases. Most of these side effects of Doxycycline+tinidazole do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Doxycycline+tinidazole or any other medicines, please tell your doctor. Avoid taking Doxycycline+tinidazole and consult a doctor before taking Doxycycline+tinidazole, if you are pregnant or breastfeeding as it may harm the baby. Tinidazole may affect fertility in both men and women. Therefore, please consult a doctor if you are planning for pregnancy before taking Doxycycline+tinidazole. Doxycycline+tinidazole is not recommended for children below 12 years as the safety and effectiveness were not established. Drive only if you are alert as Doxycycline+tinidazole may cause drowsiness, weakness, or numbness. Avoid exposure to strong sunlight as Doxycycline+tinidazole may make the skin more sensitive to sunburn than normal.
Uses of Doxycycline+tinidazole
Medicinal Benefits
Doxycycline+tinidazole is a combination of two antibiotics, namely: Doxycycline and Tinidazole. Doxycycline is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It works by inhibiting the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Tinidazole is also a broad-spectrum antibiotic that damages the DNA (genetic material) of bacteria and protozoa and inhibits new DNA formation. Thereby, kills microorganisms and preventing the spread of bacterial infection.
Directions for Use
Storage
Side Effects of Doxycycline+tinidazole
- Vomiting
- Nausea
- Diarrhoea
- Stomach pain
- Headache
- Loss of appetite
- Headache
- Skin sensitivity to sun light
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Doxycycline+tinidazole or any other medicines, please tell your doctor. If you have kidney or liver problems, myasthenia gravis (muscle weakness), porphyria (a disorder in the formation of red blood pigment), systemic lupus erythematosus (an autoimmune disease), syphilis, diarrhoea, blood disorder or fits, inform your doctor before taking Doxycycline+tinidazole. Avoid taking Doxycycline+tinidazole and consult a doctor before taking Doxycycline+tinidazole, if you are pregnant or breastfeeding, which may cause harm to the baby. Tinidazole may affect fertility in both men and women. Therefore, please consult a doctor if you are planning for pregnancy before taking Doxycycline+tinidazole. Doxycycline+tinidazole is not recommended for children below 12 years as the safety and effectiveness were not established. Drive only if you are alert as Doxycycline+tinidazole may cause drowsiness, weakness or numbness. Avoid exposure to strong sunlight as Doxycycline+tinidazole may make the skin more sensitive to sunburn than normal. Inform your doctor if you are taking oral retinoids as it may increase the risk of increased pressure in the skull. You are recommended to complete the full course of Doxycycline+tinidazole as prescribed by your doctor for effective results.
Drug Interactions
Drug-Drug Interaction: Doxycycline+tinidazole may interact with a blood thinner (warfarin), anticonvulsants (phenytoin, carbamazepine), immunosuppressant (ciclosporin) and antibiotic (nitrofurantoin).
Drug-Food Interaction: Avoid drinking beer, wine or spirits while taking Doxycycline+tinidazole and 3 days after treatment with Doxycycline+tinidazole as it may cause stomach cramps, pounding heart, stomach cramps, or flushing (sudden feeling of warmth).
Drug-Disease Interaction: If you have kidney or liver problems, myasthenia gravis (muscle weakness), porphyria (a disorder in the formation of red blood pigment), systemic lupus erythematosus (an autoimmune disease), syphilis, diarrhea, blood disorder or fits, inform your doctor before taking Doxycycline+tinidazole.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption with Doxycycline+tinidazole as it may reduce the effect of Doxycycline+tinidazole and cause adverse effects such as severe nausea, vomiting, sweating, fast heartbeats, tingling or warmth under the skin. Please consult a doctor before consuming alcohol while using Doxycycline+tinidazole.
Pregnancy
unsafeDoxycycline+tinidazole is not recommended for pregnant women as it may cause harm to the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Breast Feeding
unsafeDoxycycline+tinidazole is contraindicated in breastfeeding mothers as Doxycycline+tinidazole is excreted in human milk and may cause permanent discolouration of the tooth in the baby. Please consult a doctor if you are breastfeeding.
Driving
cautionDoxycycline+tinidazole may cause drowsiness, weakness or numbness. Therefore, drive only if you are alert after taking Doxycycline+tinidazole.
Liver
cautionTake Doxycycline+tinidazole with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Doxycycline+tinidazole with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeDoxycycline+tinidazole is not recommended for children below 12 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Take probiotics after completing the full course of Doxycycline+tinidazole to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
- Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
- Make sure you drink plenty of water or other fluids every day while you are taking Doxycycline+tinidazole.
- Avoid alcohol consumption as it may increase adverse effects.
Special Advise
- Doxycycline+tinidazole may rarely cause abnormal liver function tests. Please consult a doctor if you any concerns regarding this.
Patients Concern
Disease/Condition Glossary
Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.
FAQs
Doxycycline+tinidazole contains two antibiotics, namely: Doxycycline and Tinidazole. Doxycycline works by inhibiting the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Tinidazole works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits new DNA formation. Thereby, it kills micro-organisms and prevents the spread of bacterial infection.
Doxycycline+tinidazole may be used to treat sexually transmitted diseases such as gonorrhoea, chlamydia or syphilis caused by bacteria. Doxycycline+tinidazole is an antibiotic that kills bacteria and prevents the spread of infection. Consult a doctor before the use of Doxycycline+tinidazole.
Doxycycline+tinidazole may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Doxycycline+tinidazole and consult a doctor immediately.
You are not recommended to take Doxycycline+tinidazole with warfarin as co-administration of these two medicines may increase bleeding risk. However, please consult your doctor before taking Doxycycline+tinidazole with other medicines.
Doxycycline+tinidazole contains Doxycycline, which makes the skin more sensitive to sunburn than usual. Therefore, avoid exposure to strong UV light (sunbed) or sunlight while taking Doxycycline+tinidazole.
Doxycycline+tinidazole is not used to treat viral infections. Doxycycline+tinidazole is an antibiotic which is used to treat only bacterial infections.
