Efavirenz+lamivudine+tenofovir Disoproxil Fumarate
About
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
You should take this medicine exactly as prescribed by the doctor. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.
It is not recommended to take Efavirenz+lamivudine+tenofovir Disoproxil Fumarate if you are allergic to any contents of it. Before taking Efavirenz+lamivudine+tenofovir Disoproxil Fumarate, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, Hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should not be given to children below 2 years of age. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Uses of Efavirenz+lamivudine+tenofovir Disoproxil Fumarate
Medicinal Benefits
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
Directions for Use
Storage
Side Effects of Efavirenz+lamivudine+tenofovir Disoproxil Fumarate
- Headache
- Dizziness
- Nausea
- Insomnia (difficulty in sleeping)
- Weakness
- Depression
- Cough
- Diarrhoea
- Impaired concentration
- Abnormal dreams
- Fatigue
- Nasal congestion (stuffy nose)
- Pain
In-Depth Precautions and Warning
Drug Warnings
It is not recommended to take Efavirenz+lamivudine+tenofovir Disoproxil Fumarate if you are allergic to any contents of it. Before taking Efavirenz+lamivudine+tenofovir Disoproxil Fumarate, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should not be given to children below 2 years of age. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis.
Drug Interactions
Drug-Drug Interactions: Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may interact with drugs like anticancer (cisplatin), anti-depressant (citalopram), anti-fungal (fluconazole), antibiotics (gentamicin, ciprofloxacin, azithromycin, tobramycin), antimetabolites (methotrexate), potassium-sparing diuretics (amiodarone), anti-platelet drug (aspirin).
Drug-Food Interactions: Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoid smoking and alcohol consumption while on this medication.
Drug-Disease Interactions: Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should not be used in patients with liver disease, kidney diseases, hepatitis B or C (liver infections), CNS disorders, heart diseases, hypercholesterolemia, bone disorders, lactic acidosis, immune reconstitution syndrome.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionConsumption of alcohol may increase the risk of side-effects.
Pregnancy
cautionEfavirenz+lamivudine+tenofovir Disoproxil Fumarate is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this Efavirenz+lamivudine+tenofovir Disoproxil Fumarate.
Breast Feeding
cautionEfavirenz+lamivudine+tenofovir Disoproxil Fumarate is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.
Driving
cautionEfavirenz+lamivudine+tenofovir Disoproxil Fumarate may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Liver
cautionEfavirenz+lamivudine+tenofovir Disoproxil Fumarate should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionEfavirenz+lamivudine+tenofovir Disoproxil Fumarate should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
cautionEfavirenz+lamivudine+tenofovir Disoproxil Fumarate is not recommended for use in children below 2 years. In children above 2 years of age, dose adjustments may be necessary.
Habit Forming
Diet & Lifestyle Advise
- Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
- Wash fruits and vegetables thoroughly. Use a separate cutting board for raw meats.
- Wash hands, utensils, and cutting boards with soap and water after each use.
- Eating a diet high in vegetables, fruits, whole grains, and legumes.
- Choosing lean, low-fat sources of protein.
- Limiting sweets, soft drinks, and foods with added sugar.
- Including proteins, carbohydrates, and a little good fat in all meals and snacks.
Special Advise
- Do not stop taking Efavirenz+lamivudine+tenofovir Disoproxil Fumarate without your doctor’s advice.
- Monitor your liver function tests and kidney function tests regularly.
Patients Concern
Disease/Condition Glossary
HIV (human immunodeficiency virus): HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral agents.
FAQs
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Efavirenz+lamivudine+tenofovir Disoproxil Fumarate also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate may cause the weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should not be stopped suddenly. Inform your doctor before stopping Efavirenz+lamivudine+tenofovir Disoproxil Fumarate.
Efavirenz+lamivudine+tenofovir Disoproxil Fumarate should be used with caution in liver diseases, kidney diseases, hypercholesterolemia, CNS disorders and lactic acidosis.
