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Ergotamine+caffeine+belladonna+paracetamol

About

Ergotamine+caffeine+belladonna+paracetamol belongs to the class of medications called 'antimigraine agents' used to prevent migraine symptoms like intense throbbing in one area, headache, nausea and vomiting. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. 
 
Ergotamine+caffeine+belladonna+paracetamol contains Ergotamine (alkaloid), Caffeine (methylxanthine), Paracetamol (mild analgesic) and Belladonna (alkaloid). Ergotamine works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Belladonna works by blocking the chemicals of the nervous system. Paracetamol blocks the release of prostaglandins that cause pain and fever. Together, Ergotamine+caffeine+belladonna+paracetamol helps treat signs and symptoms of migraine.
 
You are advised to take Ergotamine+caffeine+belladonna+paracetamol for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as stomach pain, dizziness, dry mouth and diarrhoea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Ergotamine+caffeine+belladonna+paracetamol contains paracetamol, do not take other medicines containing paracetamol along with Ergotamine+caffeine+belladonna+paracetamol unless prescribed. Do not take Ergotamine+caffeine+belladonna+paracetamol if you are pregnant or breastfeeding. Ergotamine+caffeine+belladonna+paracetamol may cause dizziness, so drive with caution. Ergotamine+caffeine+belladonna+paracetamol should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Ergotamine+caffeine+belladonna+paracetamol as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Ergotamine+caffeine+belladonna+paracetamol

Migraine

Medicinal Benefits

Ergotamine+caffeine+belladonna+paracetamol is a combination of four drugs, namely: Ergotamine, caffeine, belladonna and paracetamol. Ergotamine+caffeine+belladonna+paracetamol is indicated to treat and prevent migraine. Ergotamine is an ergot alkaloid that works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headache. Caffeine is a methylxanthine which enhances the vasoconstrictive effect (narrowing of blood vessels). Belladonna works by blocking the chemicals of the nervous system. Paracetamol is an analgesic which blocks the release of prostaglandins that cause pain. Together, Ergotamine+caffeine+belladonna+paracetamol helps in treating migraine.

Directions for Use

Swallow Ergotamine+caffeine+belladonna+paracetamol as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ergotamine+caffeine+belladonna+paracetamol

  • Stomach pain
  • Dizziness
  • Dry mouth
  • Diarrhoea
  • Constipation
  • Tachycardia (increased heart rate)
  • Blurred vision

In-Depth Precautions and Warning

Drug Warnings

Do not take Ergotamine+caffeine+belladonna+paracetamol if you are allergic to any of its contents, if you have/had heart problems, blood circulation problems, or if you are taking antibiotics, anti-fungal, anti-HIV or other anti-migraine medicines. Ergotamine+caffeine+belladonna+paracetamol contains paracetamol, do not take other medicines containing paracetamol along with Ergotamine+caffeine+belladonna+paracetamol unless prescribed. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver or kidney problems. Do not take Ergotamine+caffeine+belladonna+paracetamol if you are pregnant or breastfeeding. Ergotamine+caffeine+belladonna+paracetamol may cause dizziness, so drive only if you are alert. Ergotamine+caffeine+belladonna+paracetamol is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Ergotamine+caffeine+belladonna+paracetamol as it could lead to increased dizziness. Do not take any other medicines for pain relief along with Ergotamine+caffeine+belladonna+paracetamol unless prescribed. 

Drug Interactions

Drug-Drug Interactions: Ergotamine+caffeine+belladonna+paracetamol may interact with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole), anti-HIV medicines (indinavir, nelfinavir, ritonavir), a decongestant (oxymetazoline), pain killers (acetaminophen, butalbital, fentanyl), anti-depressant (fluoxetine), anti-anxiety (diazepam), antacid (ranitidine).

Drug-Food Interactions: Avoid the consumption of alcohol and caffeinated products. Do not consume grapefruit while taking Ergotamine+caffeine+belladonna+paracetamol.

Drug-Disease Interactions: Inform your doctor if you have high blood pressure, heart problems, bipolar disorder, psychotic disorders, seizure disorders, gastroesophageal reflux disease, liver or kidney problems.

Drug-Drug Interactions Checker List:

  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TROLEANDOMYCIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • INDINAVIR
  • NELFINAVIR
  • RITONAVIR
  • OXYMETAZOLINE
  • ACETAMINOPHEN
  • FENTANYL
  • BUTALBITAL
  • FLUOXETINE
  • DIAZEPAM
  • RANITIDINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Ergotamine+caffeine+belladonna+paracetamol as it may cause increased dizziness.

    • Safety Warning

      Pregnancy

      unsafe

      Avoid taking Ergotamine+caffeine+belladonna+paracetamol if you are pregnant or planning for pregnancy. Please consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Breast Feeding

      unsafe

      Ergotamine+caffeine+belladonna+paracetamol may pass into breastmilk. Avoid taking Ergotamine+caffeine+belladonna+paracetamol if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Driving

      caution

      Ergotamine+caffeine+belladonna+paracetamol may cause dizziness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Ergotamine+caffeine+belladonna+paracetamol should not be given to children as safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
    • Avoid bright lights, loud noise, and extreme temperatures.
    • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
    • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
    • Massage your scalp to ease the pain.
    • Lie down in a quiet, dark room.
    • Place a cold cloth over your forehead or neck.
    • Avoid smoking, alcohol, and caffeinated drinks. 
    • Learn what triggers your migraine and try avoiding them.
    • Stay hydrated. Drink plenty of fluids.
    • Learn relaxation skills as they help in reducing stress.

    Patients Concern

    Disease/Condition Glossary

    Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Migraine headache is preceded by warning symptoms one or two days prior to the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, sensitivity to sound and light.

    FAQs

    Ergotamine+caffeine+belladonna+paracetamol contains Ergotamine, caffeine, belladonna, and paracetamol. Ergotamine works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headache. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Belladonna works by blocking the chemicals of the nervous system. Paracetamol blocks the release of prostaglandins that cause pain.

    Dry mouth could be a side-effect of Ergotamine+caffeine+belladonna+paracetamol. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

    Do not take Ergotamine+caffeine+belladonna+paracetamol along with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole) and anti-HIV medicines (indinavir, nelfinavir, ritonavir). Ergotamine+caffeine+belladonna+paracetamol contains ergotamine and caffeine, which, when taken along with these drugs, could lead to unpleasant side effects such as poor blood flow to hands, feet or brain.

    Diarrhoea could be a side-effect of Ergotamine+caffeine+belladonna+paracetamol. Drink plenty of fluids to prevent dehydration if you experience diarrhoea. Talk to your doctor if the condition persists or worsens.

    Avoid taking Ergotamine+caffeine+belladonna+paracetamol with large quantities of caffeinated beverages, such as tea, coffee or cola. High caffeine intake, along with Ergotamine+caffeine+belladonna+paracetamol can cause nervousness, shakiness and a fast heartbeat.

    Available Medicines for

    Ergotamine+caffeine+belladonna+paracetamol

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