Fluconazole+tinidazole
About
Fluconazole+tinidazole belongs to a class of medication called anti-infectives used to treat various fungal and bacterial infections. Also, Fluconazole+tinidazole may be used to treat infections such as giardiasis and amoebiasis (stomach infections), and trichomoniasis (genital infection) caused by protozoa. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may affect the skin and spread into bones, tissues, organs, or the whole body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly.
Fluconazole+tinidazole is a combination of two drugs, namely: Fluconazole (antifungal) and Tinidazole (antiprotozoal). The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Fluconazole belongs to the class of antifungals that works by damaging the fungal cell membranes and killing fungi. Tinidazole belongs to the class of antiprotozoals that works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, killing micro-organisms and clearing the infection.
Take Fluconazole+tinidazole as prescribed by your doctor. You are advised to take Fluconazole+tinidazole for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, diarrhea, headache, skin rash or itching, loss of appetite, stomach pain, or cramps. Most of these side effects of Fluconazole+tinidazole do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Fluconazole+tinidazole or any other medicines, please tell your doctor. Avoid taking Fluconazole+tinidazole if you are pregnant or a nursing mother and consult a doctor. Tinidazole may affect fertility in both men and women. Therefore, please consult a doctor if you are planning for pregnancy before taking Fluconazole+tinidazole. Drive only if you are alert as Fluconazole+tinidazole may cause drowsiness, dizziness, numbness, or weakness. Do not drink alcohol with Fluconazole+tinidazole as it may cause adverse effects such as severe nausea, vomiting, sweating, fast heartbeats, tingling, or warmth under the skin.
Uses of Fluconazole+tinidazole
Medicinal Benefits
Fluconazole+tinidazole is a combination of two drugs, namely: Fluconazole and Tinidazole used to treat various fungal and bacterial infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Fluconazole is an antifungal that damages the fungal cell membranes and kills fungi. Tinidazole is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It damages the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, kills micro-organisms and clears the infection.
Directions for Use
Storage
Side Effects of Fluconazole+tinidazole
- Vomiting
- Nausea
- Diarrhoea
- Dyspepsia
- Itching or burning
- Darkened urine
- Abdominal Pain
- Headache
- Skin rash or itching
- Loss of appetite
- Stomach pain or cramps
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Fluconazole+tinidazole or any other medicines, please tell your doctor. Avoid taking Fluconazole+tinidazole if you are pregnant or a nursing mother and consult a doctor. Tinidazole may affect fertility in both men and women. Therefore, please consult a doctor if you are planning for pregnancy before taking Fluconazole+tinidazole. Drive only if you are alert as Fluconazole+tinidazole may cause drowsiness, dizziness, numbness, or weakness. Do not drink alcohol with Fluconazole+tinidazole as it may cause adverse effects such as severe nausea, vomiting, sweating, fast heartbeats, tingling, or warmth under the skin. You are recommended to complete the full course of Fluconazole+tinidazole as prescribed by your doctor for effective results. If you have adrenal insufficiency (adrenal glands do not produce sufficient amounts of steroid hormones), abnormal levels of calcium, magnesium, or potassium, a blood disorder, fits, kidney, liver, or heart problems inform your doctor before taking Fluconazole+tinidazole. Avoid taking Fluconazole+tinidazole with erythromycin, pimozide, cisapride, quinidine, terfenadine, and astemizole as it may cause adverse effects.
Drug Interactions
Drug-Drug Interaction: Fluconazole+tinidazole may interact with a blood thinner (warfarin), antibiotics (rifampicin, erythromycin, rifabutin, nitrofurantoin), antidepressants (nortriptyline, amitriptyline), antifungals (voriconazole, amphotericin B), benzodiazepines (triazolam, midazolam), anticonvulsants (phenytoin, carbamazepine), pain relievers (ibuprofen, lornoxicam, meloxicam, diclofenac, celecoxib, flurbiprofen, naproxen), antiallergic drugs (astemizole, terfenadine), antipsychotic drug (pimozide), drug for stomach upset (cisapride), medicines used to lower high blood pressure (verapamil, felodipine, losartan, nifedipine, isradipine, amlodipine), antiarrhythmic agent (quinidine), anticancer drug (ibrutinib, olaparib), antiasthma drug (theophylline), anti-HIV drugs (saquinavir, zidovudine), antidiabetics (glibenclamide, glipizide, chlorpropamide, tolbutamide).
Drug-Food Interaction: Avoid drinking beer, wine or spirits while taking Fluconazole+tinidazole and for 3 days after treatment with Fluconazole+tinidazole as it may cause stomach cramps, pounding heart, stomach cramps, or flushing (sudden feeling of warmth).
Drug-Disease Interaction: If you have adrenal insufficiency (adrenal glands do not produce sufficient amounts of steroid hormones), abnormal levels of calcium, magnesium, or potassium, a blood disorder, fits, kidney, liver or heart problems inform your doctor before taking Fluconazole+tinidazole.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption with Fluconazole+tinidazole as it may cause adverse effects such as severe nausea, vomiting, sweating, fast heartbeats, tingling or warmth under the skin. Please consult a doctor before consuming alcohol while using Fluconazole+tinidazole.
Pregnancy
unsafeFluconazole+tinidazole is not recommended for pregnant women as it may cause harm to the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Breast Feeding
unsafeFluconazole+tinidazole is contraindicated in breastfeeding mothers as Fluconazole+tinidazole is excreted in human milk and may harm the baby. However, if you stop breastfeeding while on treatment with Fluconazole+tinidazole, avoid breastfeeding for at least 3 days after stopping Fluconazole+tinidazole. Please consult a doctor if you are breastfeeding.
Driving
cautionFluconazole+tinidazole may cause drowsiness, dizziness, numbness or weakness. Therefore, avoid driving if you experience any of these symptoms after taking Fluconazole+tinidazole.
Liver
cautionTake Fluconazole+tinidazole with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Fluconazole+tinidazole with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionFluconazole+tinidazole is not recommended for children below 12 years to treat bacterial infections. However, for treating other infections, Fluconazole+tinidazole should be used in doses only as prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
- In wet places such as changing rooms and gym showers, don’t walk on barefoot. Wear flip-flops or sandals to prevent fungal infections.
- Do not scratch the affected area of skin as it can spread the infection to other body parts.
- Avoid sharing towels, combs, bedsheets, shoes or socks with others to prevent the spread of infection.
- Wash your bed sheets and towels regularly.
- Avoiding getting in contact with harsh soaps, detergents and rough fabrics.
- Include fiber rich foods, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice, whole grain bread should be included in your diet.
- Make sure you drink plenty of water or other fluids every day while you are taking Fluconazole+tinidazole.
- Avoid alcohol consumption as it may increase adverse effects.
Special Advise
- Please consult a doctor if the infection persists or worsens after using Fluconazole+tinidazole for 1 week.
Patients Concern
Disease/Condition Glossary
Fungal infection: It is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may affect the skin and spread into bones, tissues, organs, or the whole body. It may be contagious (spread from one person to another). The symptoms of a fungal infection include skin rash, darkening of the skin, peeling, itching, deformed toenail, or vaginal discharge. Antifungal medicines are usually used to treat fungal infections.
Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.
FAQs
Fluconazole+tinidazole contains Fluconazole and Tinidazole. Fluconazole is an antifungal that works by damaging the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, kills fungi. Tinidazole is an antiprotozoal that works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, kills micro-organisms and clears the infection.
Fluconazole+tinidazole may be used to treat gum infections such as gingivitis (inflammation of gums) caused by bacteria. Fluconazole+tinidazole contains Tinidazole that kills bacteria and clears infection.
Fluconazole+tinidazole may cause diarrhoea as a temporary adverse effect. However, if the condition persists or worsens or if you notice blood in stools, please consult your doctor.
You are not recommended to take Fluconazole+tinidazole with erythromycin as co-administration of these medicines may increase the risk of abnormal heart rhythm. However, please consult your doctor before taking Fluconazole+tinidazole with other medicines.
Fluconazole+tinidazole may affect fertility in both men and women. Therefore, please consult a doctor if you are planning for pregnancy before taking Fluconazole+tinidazole.
Fluconazole+tinidazole may be used to treat bacterial infections. Fluconazole+tinidazole contains Tinidazole, an antiprotozoal drug that kills bacteria and protozoa.
