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Fluticasone Furoate+azelastine Hydrochloride

About

Fluticasone Furoate+azelastine Hydrochloride belongs to the class of medications called 'anti-allergic' primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods, pollen or pet dander. 

Fluticasone Furoate+azelastine Hydrochloride is a combination of two drugs, namely: Fluticasone furoate (corticosteroid) and Azelastine hydrochloride (antihistamine/antiallergic). Fluticasone furoate prevents the release of certain chemicals in the body that cause inflammatory reactions. On the other hand, Azelastine hydrochloride works by blocking the action of histamine, a substance responsible for causing allergic reactions. Together, Fluticasone Furoate+azelastine Hydrochloride provides relief from allergic symptoms.

Use Fluticasone Furoate+azelastine Hydrochloride as advised by your doctor. Your doctor will recommend how often you need to take Fluticasone Furoate+azelastine Hydrochloride based on your medical condition. Some people may experience certain common side effects, such as headache, taste changes or nose bleeds. Most of these side effects of Fluticasone Furoate+azelastine Hydrochloride do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Fluticasone Furoate+azelastine Hydrochloride or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Fluticasone Furoate+azelastine Hydrochloride. Fluticasone Furoate+azelastine Hydrochloride is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds or increased drowsiness, stop using Fluticasone Furoate+azelastine Hydrochloride and consult a doctor immediately. 

Uses of Fluticasone Furoate+azelastine Hydrochloride

Allergic symptoms.

Medicinal Benefits

Fluticasone Furoate+azelastine Hydrochloride is a combination of two drugs, namely: Fluticasone furoate and Azelastine hydrochloride used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose or watery eyes. Fluticasone furoate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining. It stops the release of certain chemicals in the body that cause inflammatory reactions, thereby providing relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine hydrochloride belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together Fluticasone Furoate+azelastine Hydrochloride relieves allergic symptoms, including seasonal allergies and reduces inflammation of nasal passage.

Directions for Use

Check the label for directions before using Fluticasone Furoate+azelastine Hydrochloride. Insert the tip of the bottle into a nostril while closing the other nostril and spray the medicine towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fluticasone Furoate+azelastine Hydrochloride

  • Headache
  • Taste changes
  • Nose bleeds

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Fluticasone Furoate+azelastine Hydrochloride or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Fluticasone Furoate+azelastine Hydrochloride. Fluticasone Furoate+azelastine Hydrochloride is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds or increased drowsiness, stop using Fluticasone Furoate+azelastine Hydrochloride and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Fluticasone Furoate+azelastine Hydrochloride may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers or sores inside the nose, inform your doctor before using Fluticasone Furoate+azelastine Hydrochloride.

Drug Interactions

Drug-Drug Interaction: Fluticasone Furoate+azelastine Hydrochloride may interact with antidepressants (duloxetine, escitalopram), anticonvulsants (pregabalin), HIV/AIDS drug (ritonavir), antifungals (ketoconazole, fluconazole, itraconazole) and anti-allergy drugs (cetirizine).

Drug-Food Interaction: Fluticasone Furoate+azelastine Hydrochloride may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Fluticasone Furoate+azelastine Hydrochloride as it may lead to adrenal insufficiency and Cushing’s syndrome. Also, avoid consumption of alcohol with Fluticasone Furoate+azelastine Hydrochloride as it may cause increased drowsiness, dizziness, and impairment of judgement and thinking.

Drug-Disease Interaction: If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers or sores inside the nose, inform your doctor before using Fluticasone Furoate+azelastine Hydrochloride.

Drug-Drug Interactions Checker List:

  • DULOXETINE
  • ESCITALOPRAM
  • PREGABALIN
  • RITONAVIR
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ITRACONAZOLE
  • CETIRIZINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Fluticasone Furoate+azelastine Hydrochloride as it may increase adverse effects. Please consult a doctor before consuming alcohol with Fluticasone Furoate+azelastine Hydrochloride.

    • Safety Warning

      Pregnancy

      caution

      The safety of Fluticasone Furoate+azelastine Hydrochloride in pregnant women is unknown. Please consult a doctor. It is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Fluticasone Furoate+azelastine Hydrochloride is excreted in human milk. Please consult a doctor. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

    • Safety Warning

      Driving

      caution

      Fluticasone Furoate+azelastine Hydrochloride may cause drowsiness in some people. Therefore, drive only if you are alert after using Fluticasone Furoate+azelastine Hydrochloride.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of Fluticasone Furoate+azelastine Hydrochloride in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of Fluticasone Furoate+azelastine Hydrochloride in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      caution

      Fluticasone Furoate+azelastine Hydrochloride is not recommended for children below 6 years as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
    • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from a runny nose, cough, and sneezing.
    • The immune system is affected by stress and raises the risk of being sick. Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress.
    • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, and certain food items that are known to cause allergies to you.
    • Maintain personal hygiene and keep your surroundings clean.

    Special Advise

    Certain blood tests are recommended while using Fluticasone Furoate+azelastine Hydrochloride to monitor serum cortisol levels as Fluticasone Furoate+azelastine Hydrochloride may increase these levels.

    Patients Concern

    Disease/Condition Glossary

    Allergy: It is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to the body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods, pollen or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

    FAQs

    Fluticasone Furoate+azelastine Hydrochloride contains Fluticasone furoate and Azelastine hydrochloride. Fluticasone furoate works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Azelastine hydrochloride is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

    You are recommended to avoid consuming grapefruit and grapefruit juice with Fluticasone Furoate+azelastine Hydrochloride as they may lead to adrenal insufficiency and Cushing’s syndrome.

    Fluticasone Furoate+azelastine Hydrochloride may cause drowsiness in some people, especially in people consuming alcohol with Fluticasone Furoate+azelastine Hydrochloride. Therefore, avoid driving if you feel drowsy after using Fluticasone Furoate+azelastine Hydrochloride.

    You are not recommended to take more than the prescribed dose of Fluticasone Furoate+azelastine Hydrochloride or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while using Fluticasone Furoate+azelastine Hydrochloride, please consult a doctor immediately.

    Fluticasone Furoate+azelastine Hydrochloride is not intended for the treatment of asthma attacks. Fluticasone Furoate+azelastine Hydrochloride is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.

    You are not recommended to stop using Fluticasone Furoate+azelastine Hydrochloride without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Fluticasone Furoate+azelastine Hydrochloride for as long as your doctor has prescribed it, and if you experience any difficulty while using Fluticasone Furoate+azelastine Hydrochloride, please consult your doctor.

    You should avoid using Fluticasone Furoate+azelastine Hydrochloride and consult a doctor before using if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.

    Available Medicines for

    Fluticasone Furoate+azelastine Hydrochloride

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