Gabapentin+methylcobalamin+nortriptyline
About
Gabapentin+methylcobalamin+nortriptyline is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).
Gabapentin+methylcobalamin+nortriptyline contains Gabapentin, methylcobalamin, and nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Methylcobalamin helps protect and rejuvenate the nerve cells and nerve fibres. Together, Gabapentin+methylcobalamin+nortriptyline helps in providing relief from neuropathic pain.
You are advised to take Gabapentin+methylcobalamin+nortriptyline for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Gabapentin+methylcobalamin+nortriptyline may cause dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Consult your doctor if you are pregnant or breastfeeding. Gabapentin+methylcobalamin+nortriptyline may cause sleepiness and dizziness, so drive only if you are alert. Limited data is available regarding the usage of Gabapentin+methylcobalamin+nortriptyline in children, so please consult a doctor if you have any concerns. Avoid consuming alcohol with Gabapentin+methylcobalamin+nortriptyline as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.
Uses of Gabapentin+methylcobalamin+nortriptyline
Medicinal Benefits
Gabapentin+methylcobalamin+nortriptyline contains Gabapentin (anti-convulsant), Methylcobalamin (vitamin), and Nortriptyline (tricyclic antidepressant). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline works by increasing the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Methylcobalamin helps protect and rejuvenate the nerve cells and nerve fibres. Together, Gabapentin+methylcobalamin+nortriptyline helps in providing relief from neuropathic pain.
Directions for Use
Storage
Side Effects of Gabapentin+methylcobalamin+nortriptyline
- Dizziness
- Sleepiness
- Tiredness
- Headache
- Nausea
- Vomiting
- Dry mouth
- Constipation
In-Depth Precautions and Warning
Drug Warnings
Do not take Gabapentin+methylcobalamin+nortriptyline if you are allergic to any of its contents. Inform your doctor if you have/had heart problems, bipolar syndrome, thyroid disorder, epilepsy, high blood pressure, diabetes, urinary retention, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Gabapentin+methylcobalamin+nortriptyline may cause sleepiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Gabapentin+methylcobalamin+nortriptyline as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Drug Interactions
Drug-Drug Interactions: Gabapentin+methylcobalamin+nortriptyline may interact with hypnotics (zolpidem), antidepressants (duloxetine, escitalopram, sertraline), pain killers (hydrocodone, acetaminophen), anti-histamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), anti-convulsant (pregabalin, topiramate), anti-anxiety (alprazolam), anti-emetic (ondansetron).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have heart problems, pheochromocytoma (tumour of the adrenal gland), depression, seizures, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, glaucoma, diabetes, thyroid problems, suicidal tendency, hemodialysis, kidney or liver problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Gabapentin+methylcobalamin+nortriptyline as it may cause increased dizziness and sleepiness.
Pregnancy
cautionPlease consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor if you are breastfeeding; your doctor will decide whether Gabapentin+methylcobalamin+nortriptyline can be taken by breastfeeding mothers or not.
Driving
cautionGabapentin+methylcobalamin+nortriptyline may cause dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
cautionLimited information is available regarding the usage of Gabapentin+methylcobalamin+nortriptyline in children. Please consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Include food rich in vitamin B and D in your diet.
- Exercising regularly helps in improving overall health and combating pain.
- Rest well. Get optimum sleep.
- Include cayenne pepper in your diet, as it can help in lowering neuropathic pain.
- Try taking a warm bath, as it can be soothing.
- Avoid smoking and alcohol consumption.
- Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
- Acupuncture can be helpful by stimulating pressure points.
- Using essential oils for massages can help increase circulation.
Patients Concern
Disease/Condition Glossary
Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It occurs by chronic progressive nerve disease, infection, or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).
FAQs
Gabapentin+methylcobalamin+nortriptyline works by binding to the specific site on voltage-gated calcium channels and decreases the movement of pain receptors. It also helps protect and rejuvenate the nerve cells and nerve fibres.
Gabapentin+methylcobalamin+nortriptyline may cause constipation. Eat fibre-rich food and drink plenty of fluids if you experience constipation. If the condition persists or worsens, consult a doctor.
To treat your condition effectually, continue taking Gabapentin+methylcobalamin+nortriptyline for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Gabapentin+methylcobalamin+nortriptyline.
Dry mouth could be a side-effect of Gabapentin+methylcobalamin+nortriptyline. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Gabapentin+methylcobalamin+nortriptyline may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet. Consult your doctor if you have any concerns.
