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Insulin Aspart Protamine

About

Insulin Aspart Protamine is an intermediate-acting human insulin analogue used to lower blood glucose levels in people with diabetes mellitus. Diabetes occurs when the body does not produce enough insulin to control the level of blood sugar. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above average.
 
Insulin Aspart Protamine contains ‘Insulin aspart protamine’, which works in a similar manner as the insulin produced by the body. It suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells. Thereby, Insulin Aspart Protamine helps in controlling the blood glucose levels.
 
You are advised to take Insulin Aspart Protamine for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as hypoglycaemia (low blood glucose levels), injection site reactions, rash, and itching sensations. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult your doctor if you experience these side effects persistently.
 
Do not skip any doses or stop taking Insulin Aspart Protamine suddenly without consulting your doctor as it may lead to increased blood glucose levels. Consult your doctor if you are pregnant or breastfeeding. Insulin Aspart Protamine should not be given to children below 10 years. Avoid alcohol consumption while taking Insulin Aspart Protamine as it might increase side-effects. Insulin Aspart Protamine may cause hypoglycaemia, so drive only if you are alert. Inform your doctor about all the medications you are taking and your health condition to rule out any unpleasant side effects.

Uses of Insulin Aspart Protamine

Diabetes

Medicinal Benefits

Insulin Aspart Protamine is an intermediate-acting human insulin analogue used to lower the blood glucose levels in people with diabetes mellitus. Insulin Aspart Protamine works in a similar manner as the insulin produced by the body. It suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells. Thereby, Insulin Aspart Protamine helps in controlling the blood glucose levels. 

Directions for Use

Insulin Aspart Protamine should be administered sub-cutaneous only. Wash your hands properly and adjust the dose as advised by the doctor. Clean the injection site and inject the dose subcutaneously in the abdomen area. Safely discard the needle. Your doctor will advise for how long you need to take Insulin Aspart Protamine based on your medical condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Insulin Aspart Protamine

  • Hypoglycaemia (low blood glucose levels)
  • Local injection site reactions
  • Rash
  • Itching sensation

In-Depth Precautions and Warning

Drug Warnings

Do not take Insulin Aspart Protamine if you are allergic to any of its contents. Inform your doctor if you have adrenal, pituitary, thyroid glands, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Insulin Aspart Protamine should not be given to children below 10 years. Avoid alcohol consumption while taking Insulin Aspart Protamine as it might increase side-effects. Insulin Aspart Protamine may cause hypoglycaemia, so drive only if you are alert. 

Drug Interactions

Drug-Drug Interactions: Insulin Aspart Protamine may interact with somatostatin analogues (octreotide), anti-diabetic (pioglitazone), androgen (danazol)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have heart diseases, hypoglycemia (low blood glucose levels), hyperkalemia (low potassium levels), kidney, or liver problems.

Drug-Drug Interactions Checker List:

  • OCTREOTIDE
  • PIOGLITAZONE
  • DANAZOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption while taking Insulin Aspart Protamine to prevent unpleasant side effects.

    • Safety Warning

      Pregnancy

      caution

      Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      It is safe to use Insulin Aspart Protamine by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Driving

      caution

      Insulin Aspart Protamine may cause hypoglycaemia. So, drive, and operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Insulin Aspart Protamine should be used with caution in patients with liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Insulin Aspart Protamine should be used with caution in patients with kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Insulin Aspart Protamine is not recommended for children below 10years.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.
    • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
    • Follow a healthy diet and walk for at least 45 minutes to complement treatment with Insulin Aspart Protamine.
    • Maintain a healthy weight by exercising regularly.
    • Rest properly, avoid stress by doing meditation or yoga.

    Special Advise

    • Regularly monitor blood glucose levels while taking Insulin Aspart Protamine.
    • Try not to skip any doses and take Insulin Aspart Protamine for as long as your doctor has prescribed it for you.
    • To avoid contamination, always use a new needle for each injection.
    • Always check the cartridge and rubber plunger for any leakage.

    Patients Concern

    Disease/Condition Glossary

    Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in your blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types, namely: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

    FAQs

    Insulin Aspart Protamine suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells. Thereby, Insulin Aspart Protamine helps in controlling the blood glucose levels.

    Insulin Aspart Protamine may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Insulin Aspart Protamine. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.

    Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Insulin Aspart Protamine is taken along with other antidiabetic medicines.

    Avoid skipping meals. Maintain a healthy diet by regular intake of good food. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.

    Do not stop taking Insulin Aspart Protamine without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Insulin Aspart Protamine for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Insulin Aspart Protamine.

    Available Medicines for

    Insulin Aspart Protamine

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