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Ketorolac Tromethamine

About

Ketorolac Tromethamine belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAID) indicated for the short-term management of moderate to severe acute postoperative pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body.
 
Ketorolac Tromethamine contains 'ketorolac tromethamine', which works by inhibiting the synthesis of certain chemical messengers in the body, such as prostaglandins which are responsible for causing pain and inflammation. Thereby, Ketorolac Tromethamine helps provide relief from pain.
 
In some cases, you may experience common side effects such as nausea, vomiting, stomach upset, diarrhoea, constipation, gas, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Avoid taking Ketorolac Tromethamine if you are pregnant or breastfeeding. Ketorolac Tromethamine should not be given to children below 16 years as safety and efficacy have not been established. Avoid consuming alcohol with Ketorolac Tromethamine as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Ketorolac Tromethamine

Postoperative pain relief

Medicinal Benefits

Ketorolac Tromethamine belongs to a group of medicines called  Non-Steroidal Anti-Inflammatory Drugs (NSAID) indicated for the short-term management of moderate to severe acute postoperative pain. Ketorolac Tromethamine contains 'ketorolac tromethamine', which works by inhibiting the synthesis of certain chemical messengers in the body, such as prostaglandins which are responsible for causing pain and inflammation. Thereby, Ketorolac Tromethamine helps provide relief from pain.

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water; do not chew or break the tablet/capsule. Tablet DT: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ketorolac Tromethamine

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Gas
  • Stomach upset
  • Dizziness

In-Depth Precautions and Warning

Drug Warnings

Do not take Ketorolac Tromethamine if you are allergic to any of its contents; if you have/had asthma, severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines. Ketorolac Tromethamine can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart surgery, do not take Ketorolac Tromethamine. Inform your doctor if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Avoid taking Ketorolac Tromethamine if you are pregnant or breastfeeding. Ketorolac Tromethamine may cause dizziness, so drive only if you are alert. Ketorolac Tromethamine is not recommended for children below 16 years as safety and effectiveness have not been established. Stop taking Ketorolac Tromethamine and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Ketorolac Tromethamine unless prescribed. 

Drug Interactions

Drug-Drug Interactions: Ketorolac Tromethamine may have interaction with a blood thinner (warfarin, heparin), antipsychotic agent (lithium), pain killers (aspirin), uricosuric (probenecid), antiprogestational steroids (mifepristone).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have stomach ulcer or perforation, bleeding problems, heart problems, blood circulation problems, asthma, fluid retention, thrombosis, porphyria, anaemia, high blood pressure, kidney or liver problems.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • HEPARIN
  • LITHIUM
  • ASPIRIN
  • PROBENECID
  • MIFEPRESTONE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Ketorolac Tromethamine as it may cause increased dizziness. It may also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      unsafe

      Avoid taking Ketorolac Tromethamine if you are pregnant or planning for pregnancy. Please consult your doctor if you have any concerns.

    • Safety Warning

      Breast Feeding

      unsafe

      Ketorolac Tromethamine is not recommended during breastfeeding as Ketorolac Tromethamine might pass into breastmilk.

    • Safety Warning

      Driving

      caution

      Ketorolac Tromethamine may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Ketorolac Tromethamine is not recommended for patients with advanced renal impairment and patients at risk for renal failure.

    • Safety Warning

      Children

      unsafe

      Ketorolac Tromethamine is recommended for children below 16years as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
    • Massages can also be helpful.
    • Avoid freezing and hot temperatures.
    • Avoid wearing tight-fitting clothes; instead, wear loose garments.
    • Rest well, and get plenty of sleep.
    • To avoid developing pressure sores, change your position every two hours.
    • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
    • Stay hydrated, drink plenty of water.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, and stomach ache.

    FAQs

    Ketorolac Tromethamine works by inhibiting the synthesis of certain chemical messengers which are responsible for causing pain and inflammation. Thereby, Ketorolac Tromethamine helps provide relief from pain.

    Diarrhoea might be a side-effect of Ketorolac Tromethamine. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

    Do not take any other pain killer medicines along with Ketorolac Tromethamine unless prescribed, as it might lead to unpleasant side effects and can increase the risk of stomach bleeding associated with NSAIDs.

    Ketorolac Tromethamine is usually prescribed for less than 5 days. It should not be taken for longer durations. The lowest possible dose for the shortest duration is advised. Take Ketorolac Tromethamine only for as long as your doctor has prescribed. Avoid taking Ketorolac Tromethamine for longer durations as it might increase the risk of heart problems and stomach bleeding.

    Ketorolac Tromethamine might affect fertility. Therefore, Ketorolac Tromethamine is not recommended for women trying to conceive. Please consult your doctor if you have any concerns.

    Available Medicines for

    Ketorolac Tromethamine

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