Lomefloxacin
About
Lomefloxacin belongs to the group of antibiotic medicines called fluoroquinolones indicated in the treatment of mild to moderate bacterial infections such as urinary tract infections and bronchitis. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.
Lomefloxacin contains Lomefloxacin, that works by interfering with the activity of topoisomerase IV and DNA gyrase, which are necessary for the transcription and replication of bacterial DNA. Thereby, Lomefloxacin fights bacteria in the body and treats bacterial infection.
In some cases, Lomefloxacin may cause side effects such as diarrhoea, nausea, vomiting, drowsiness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.
Consult the doctor if you are pregnant or breastfeeding. Lomefloxacin is not recommended for children below 18 years as it might interfere with bone development. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.
Uses of Lomefloxacin
Medicinal Benefits
Lomefloxacin belongs to the group of antibiotic medicines called fluoroquinolones indicated in the treatment of mild to moderate bacterial infections such as urinary tract infections and bronchitis (inflammation of the airways). Lomefloxacin contains Lomefloxacin, that works by interfering with the activity of topoisomerase IV and DNA gyrase, which are necessary for the transcription and replication of bacterial DNA. Thereby, Lomefloxacin fights bacteria in the body and treats bacterial infection.
Directions for Use
Storage
Side Effects of Lomefloxacin
- Nausea
- Vomiting
- Diarrhoea
- Headache
- Drowsiness or lightheadedness
In-Depth Precautions and Warning
Drug Warnings
Do not take Lomefloxacin if you are allergic to any of its components. Avoid exposure to direct and indirect sunlight (even when using sunscreen) while on treatment with Lomefloxacin and for several days following the treatment, as it may cause skin sensitivity to sunlight. The risk of phototoxicity can be reduced by taking Lomefloxacin in the evening, at least 12 hours before exposure to the sun. Lomefloxacin should be discontinued if signs or symptoms of photosensitivity such as sensation of skin burning, swelling, redness, rash, blisters, dermatitis or itching occur. Lomefloxacin may cause peripheral neuropathy and tendon effects. Consult the doctor if you experience symptoms of peripheral neuropathy such as pain, burning, tingling, numbness, and /or weakness, (or) symptoms of tendon effects like pain, inflammation, or rupture of a tendon. Let the doctor know if you have kidney problems, seizures or epilepsy.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking steroids (dexamethasone), anti-diabetic (glipizide), and NSAID (aspirin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform the doctor if you have colitis, CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy, tendonitis (inflammation of tendons), diabetes, crystalluria (presence of crystals in urine), or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known if alcohol interacts with Lomefloxacin. Please consult a doctor.
Pregnancy
cautionConsult the doctor if you are pregnant. Lomefloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Breast Feeding
cautionConsult the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the treatment to the mother.
Driving
cautionLomefloxacin may cause dizziness. Be cautious while driving or operating heavy machinery. Avoid activities requiring alertness if you experience dizziness.
Liver
cautionLimited information was available about using Lomefloxacin in patients with liver disease. Inform your doctor before receiving the Lomefloxacin if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionModification of dosage is recommended in patients with kidney dysfunction, So inform your doctor if you have a history of kidney disease.
Children
unsafeLomefloxacin is not recommended for children below 18 years as the safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
- Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
- Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
- Avoid consumption of alcohol and usage of tobacco.
Special Advise
- Drink plenty of fluids every day to prevent lomefloxacin crystals from forming in the urine.
- If you experience diarrhoea, consult the doctor, as anti-bacterial agents may cause pseudomembranous colitis (severe inflammation of the inner lining of the large intestine).
- Maintain a gap of 2 hours between Lomefloxacin and vitamin/mineral supplements.
- Sucralfate and antacids containing aluminium or magnesium should not be taken within 4 hours before or 2 hours after taking Lomefloxacin.
Patients Concern
Disease/Condition Glossary
Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any body part and multiply very quickly. Generalised symptoms of bacterial infection include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.
FAQs
Lomefloxacin works by interfering with the activity of enzymes which are necessary for bacterial DNA replication. Thereby, it helps treat bacterial infections.
Your symptoms may begin to improve before the infection is completely treated. Therefore, even if you begin to feel better, continue taking Lomefloxacin for as long as your doctor has prescribed it.
Lomefloxacin may make the skin more sensitive to sunlight and might result in severe sunburn. Therefore, avoid exposure to both direct and indirect sunlight during treatment with Lomefloxacin and for a few days after the treatment ends. Consult the doctor if you experience severe burning, redness, swelling, blistering, or itching.
Consult the doctor before taking vitamin/mineral supplements, as they might decrease the effects of lomefloxacin if taken at the same time. Maintaining a gap of 2 hours between Lomefloxacin and vitamin/mineral supplements is advised.