Methylcobalamin+dosulepin
About
Methylcobalamin+dosulepin belongs to the class of medications called antidepressants used in the treatment of depression. Depression is a neurological disease. It is a mood disorder characterized by persistent feelings of sadness, loss, or anger. This condition can also be triggered by vitamin b12 deficiency. Your doctor prescribes Methylcobalamin+dosulepin when other medications are ineffective to treat depression.
Methylcobalamin+dosulepin is a combination of two medicines: Dosulepine and Methylcobalamin. Dosulepin is a tricyclic antidepressant that increases neurotransmitter's activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.
The dose is determined by your doctor based on your health condition. The common side-effects of Methylcobalamin+dosulepin are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.
Do not take Methylcobalamin+dosulepin if you are allergic to any content of it. Do not take Methylcobalamin+dosulepin if you have an irregular heartbeat or any other heart problems, liver problems, eye condition known as glaucoma, prostate problems in men (difficulty in passing water or enlarged prostate), mania (feeling over-excited with unusual behaviour), and epilepsy (fits). It should be used with caution in young adults as it can increase worsen depression and cause suicidal thoughts. If you have thoughts of harming yourself, consult your doctor immediately. Inform your doctor if you are pregnant or breastfeeding.
Uses of Methylcobalamin+dosulepin
Medicinal Benefits
Methylcobalamin+dosulepin is a combination of two medicines: Dosulepine and Methylcobalamin. Your doctor prescribes this medication when other medications are ineffective to treat depression. Dosulepin is a tricyclic antidepressant that increases neurotransmitters' activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.
Directions for Use
Storage
Side Effects of Methylcobalamin+dosulepin
- Dry mouth
- Blurred vision
- Headache
- Increase or decrease in appetite
- Nausea or vomiting
- Diarrhoea
- Changes in heartbeat
- Constipation
- Difficulty in passing urine
- Sweating
In-Depth Precautions and Warning
Drug Warnings
Before taking Methylcobalamin+dosulepin, inform your doctor if you are undergoing surgery, have diabetes, receiving electroshock therapy (ECT), have thyroid problems, difficulty in passing urine, adrenal gland tumour, have porphyria (disease-causing damage to the nerves and skin sensitivity), have a history of mania or psychosis, have cardiac disease, have severe renal disease, and have epilepsy (fits). It increases suicidal tendencies, especially in young adults.
Drug Interactions
Drug-Drug Interaction: Methylcobalamin+dosulepin may interact with other antidepressants, antihypertensives, medications used to treat heart disorders, antacid (omeprazole and cimetidine), antimalarial drug (halofantrine), antiallergy medicines (terfenadine and astemizole), pain killer (tramadol), local anaesthetics, antiepileptic drugs (phenytoin, primidone, and carbamazepine), estrogen-containing birth control pills, anticoagulant (warfarin), a medicine used to treat HIV (ritonavir), antibiotic (neomycin), and antibacterial (rifampicin).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Methylcobalamin+dosulepin should not be used in patients with heart disorders, liver problems, glaucoma (an eye condition), prostate problems in men, mania (feeling over-excited with unusual behaviour), and epilepsy (fits).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol increases the risk of side-effects.
Pregnancy
unsafeMethylcobalamin+dosulepin is a category C drug. So, it is not recommended for use in pregnant women.
Breast Feeding
cautionMethylcobalamin+dosulepin should be used with caution in breastfeeding mothers.
Driving
cautionMethylcobalamin+dosulepin may cause drowsiness. So, do not drive or operate heavy machinery while taking this medicine.
Liver
cautionMethylcobalamin+dosulepin should be used with caution in patients with liver diseases. Dose adjustments may be necessary.
Kidney
cautionMethylcobalamin+dosulepin should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.
Children
cautionMethylcobalamin+dosulepin should not be used in children below 12 years of age without a doctor's advice.
Habit Forming
Diet & Lifestyle Advise
- Eat a well-balanced diet.
- Avoid processed or packed foods and foods that are high in refined sugars.
- Exercise regularly.
- Lose excess weight and keep a check on your weight.
- Avoid stress.
- Improve your mood by being active, socializing with others, and talking about your feelings.
- Quit alcohol intake and smoking.
Patients Concern
Disease/Condition Glossary
Depression: Depression is a mental health disorder in which patients experience persistent loss of interest or mood and feelings of sadness. It affects quality-of-life. It causes changes in sleep, appetite, social behaviour, learning abilities, concentration, and self-esteem. This condition can also be triggered by vitamin B12 (cyanocobalamin) deficiency.
FAQs
Methylcobalamin+dosulepin contains Dosulepin and Methylcobalamin. It treats depression by enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. It also treats vitamin B12 deficiency which is a risk factor for depression.
Methylcobalamin+dosulepin should not be used in patients with heart problems as it may worsen the condition. Discuss with your doctor about the potential benefits and risks before using Methylcobalamin+dosulepin.
The common side-effects of Methylcobalamin+dosulepin are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.
Methylcobalamin+dosulepin should not be used in patients with thyroid problems as it may exacerbate the condition by causing iatrogenic effects (drug-inducing side-effects). So, discuss the risks and benefits of this medication with your doctor before using Methylcobalamin+dosulepin.
Methylcobalamin+dosulepin increases suicidal thoughts and worsens the depression in young adults. Your doctor may prescribe this medicine with dose adjustments. So, do not use Methylcobalamin+dosulepin without consulting your doctor.
