Metronidazole+nicotinamide
About
Metronidazole+nicotinamide belongs to the class of medicine known as an antibiotic. This combination medicine is primarily used to treat acne. Acne or acne vulgaris is a long-term skin problem caused when hair follicles become plugged with oil and dead skin cells. It leads to the formation of blackheads, whiteheads, pimples, oily skin and a scar on the uppermost layer of the skin (epidermis).
Metronidazole+nicotinamide is composed of two medicines namely: Metronidazole and Nicotinamide. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne. Together they effectively help in treating acne by preventing or stopping bacterial growth.
Use Metronidazole+nicotinamide as prescribed by your doctor. Your doctor will recommend how often you take Metronidazole+nicotinamide based on your medical condition. Some people may experience dry skin and application site reactions such as irritation, burning, redness, and itching). Most of these side effects of Metronidazole+nicotinamide do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Metronidazole+nicotinamide should not be taken if you are allergic to Metronidazole+nicotinamide or any other contents present in it. Avoid unnecessary and prolonged use of Metronidazole+nicotinamide as it causes unpleasant side effects. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Metronidazole+nicotinamide. Metronidazole+nicotinamide should not be used for children less than 18 years of age as safety and efficacy of Metronidazole+nicotinamide for children has not established. Metronidazole+nicotinamide has no known effects on the ability to drive and using machines.
Uses of Metronidazole+nicotinamide
Medicinal Benefits
Metronidazole+nicotinamide is composed of two medicines namely: metronidazole and nicotinamide. Metronidazole+nicotinamide is primarily used to treat acne. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a synthetic form of Vitamin B3, that stimulates ceramide (fats found on the uppermost layer of the skin) synthesis and improves the epidermal permeability barrier functions, making skin look supple and soft. This combination of Metronidazole+nicotinamide is thus efficient for treating acne.
Directions for Use
Storage
Side Effects of Metronidazole+nicotinamide
- Dry skin
- Irritation
- Burning
- Redness
- Itching
- Rashes
In-Depth Precautions and Warning
Drug Warnings
Metronidazole+nicotinamide is meant for only topical use only and not for oral, ophthalmic or intravaginal use. You should not use a Metronidazole+nicotinamide if your skin is very sensitive or allergic to Metronidazole+nicotinamide. Do not apply Metronidazole+nicotinamide on the cut, scraped, sunburned or eczema-affected skin part. Accidently Metronidazole+nicotinamide gets into your eyes, immediately rinse your eyes with water thoroughly and contact your doctor immediately if the irritation persists. Inform your doctor if your skin conditions do not improve. Metronidazole+nicotinamide may take time to treat acne, so do not apply dosage more than prescribed for better and faster results. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Metronidazole+nicotinamide. Metronidazole+nicotinamide should not be used for children less than 18 years of age as safety and efficacy of Metronidazole+nicotinamide for children has not established. Metronidazole+nicotinamide has no known effects on the ability to drive and using machines.
Drug Interactions
Drug-Drug Interaction: Metronidazole+nicotinamide may interact with a blood thinner (warfarin, dicoumarin), birth control pills (ethinyl estradiol), and antihyperlipidemic (atorvastatin ).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Metronidazole+nicotinamide may interact with liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThere are no interactions found with Metronidazole+nicotinamide pertaining to alcohol. However, it is advised to avoid alcohol for a speedy recovery.
Pregnancy
cautionMetronidazole+nicotinamide should be used for pregnant women unless if clearly needed. Consult with your doctor before using Metronidazole+nicotinamide.
Breast Feeding
cautionMetronidazole+nicotinamide should be used for pregnant women unless if clearly needed. Consult with your doctor before using Metronidazole+nicotinamide.
Driving
safe if prescribedMetronidazole+nicotinamide usually does not affect your ability to drive or operate machinery.
Liver
cautionMetronidazole+nicotinamide to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionMetronidazole+nicotinamide to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeMetronidazole+nicotinamide should not be used for children less than 18 years of age as safety and efficacy of Metronidazole+nicotinamide for children has not established.
Habit Forming
Diet & Lifestyle Advise
- Avoid fried food or oil food and drink plenty of water
- It is advised to avoid unnecessary exposure to the sun.
- In case, it is necessary to go out in the sun, use sunscreen.
- Do not itch or scratch the infected area.
- Use moisturizer to prevent the occurrence of side effects
- Exercise regularly to reduce stress
Special Advise
- Do not use Metronidazole+nicotinamide on broken, cut , abrasion or burnt skin.
- Do not apply just on the pimples, apply on the area effected by the pimples.
Patients Concern
Disease/Condition Glossary
Acne is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, red, large and tender bumps.
FAQs
Dry skin is the most common side effect of Metronidazole+nicotinamide. Avoid alcohol-based products and use skin moisturizers to avoid dryness.
It is advised to keep and store this medicine in the container or the pack in which it came in and keep it tightly closed. Keep away from pets, children and other people.
Metronidazole+nicotinamide is composed of two medicines namely: Metronidazole and nicotinamide. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne. Together they effectively help in treating acne.
Yes, you can do makeup, but you have to choose the products cautiously. Avoid using harsh and greasy cosmetics on your face. Some products may results acne. This form of acne is known as acne cosmetica. Occasionally women who do not have acne can grow acne cosmetica because of makeup wearing.
No, only two times face washing is sufficient. Washing your face too frequently may lead to irritation and dryness and worsen acne. It is recommended by your doctor to use medicated face wash for acne.
Metronidazole+nicotinamide should not be used if you have the following conditions such as hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
