Nimesulide+pseudoephedrine+cetirizine
About
Nimesulide+pseudoephedrine+cetirizine is a combination of respiratory medication used to treat common cold symptoms, such as sneezing, runny nose, nasal and sinus congestion, stuffy nose, or watery eyes. The common cold is a respiratory illness that affects the nose and throat and is caused by viruses known as 'rhinoviruses'. The virus enters the body through the nose, mouth, or eyes and spreads easily through air droplets when a sick person sneezes, coughs, or talks.
Nimesulide+pseudoephedrine+cetirizine consists of three medicines, namely: Nimesulide (pain killer), Pseudoephedrine (decongestant), and Cetirizine (anti-allergic). Nimesulide works by blocking the effect of a chemical known as prostaglandin (PGs) that is responsible for pain, fever, and inflammation (swelling and redness) in our body. Pseudoephedrine belongs to the class of decongestant drugs. It works by reducing the swelling of blood vessels in your nose, this helps mucus and airflow more freely in the cavities in your nose (sinuses), helping you breathe more easily. Cetirizine is an antihistamine (anti-allergic) drug that reduces the effects of histamine, a chemical substance that causes allergies like runny nose and skin rash. Together, it relieves the common cold symptoms.
Take Nimesulide+pseudoephedrine+cetirizine as prescribed by your doctor. You are advised to take Nimesulide+pseudoephedrine+cetirizine for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, vomiting, diarrhea, dryness in the mouth, fatigue, insomnia (difficulty in sleeping), sleepiness, nervousness, dizziness, restlessness, headache, and increased liver enzymes. Most of these side effects of Nimesulide+pseudoephedrine+cetirizine do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Let your doctor know if you have any allergic reactions to medicines. It is mandatory to inform your doctor if you have heart, liver, kidney diseases, gastrointestinal disorders, stomach ulcers, prostate enlargement, urinary retention, diabetes, and eye disorders like cataracts and glaucoma before taking Nimesulide+pseudoephedrine+cetirizine. Nimesulide+pseudoephedrine+cetirizine contains Nimesulide which causes an increased chance of problems with joints and tissues around joints in children under 18 years. So, let your doctor know if your children have any joint problems during or after treatment with Nimesulide+pseudoephedrine+cetirizine. You get severe sunburn or blisters on your skin as an intake of Nimesulide+pseudoephedrine+cetirizine may increase the sensitivity of the skin. Please check with your doctor if you are pregnant or breastfeeding. Avoid alcohol while taking Nimesulide+pseudoephedrine+cetirizine, since it can worsen the side effects like dizziness and sleepiness.
Uses of Nimesulide+pseudoephedrine+cetirizine
Medicinal Benefits
Nimesulide+pseudoephedrine+cetirizine is a combination of respiratory medication used to treat common cold symptoms, such as sneezing, runny nose, nasal and sinus congestion, stuffy nose, or watery eyes. Nimesulide+pseudoephedrine+cetirizine consists of Nimesulide (pain killer), Pseudoephedrine (decongestant), and Cetirizine (anti-allergic). Nimesulide works by blocking the effect of a chemical known as prostaglandin (PGs) that is responsible for pain, fever, and inflammation (swelling and redness) in our body. Pseudoephedrine belongs to the class of decongestant drugs. It works by reducing the swelling of blood vessels in your nose, this helps mucus and airflow more freely in the cavities in your nose (sinuses), helping you breathe more easily. Cetirizine is an antihistamine (anti-allergic) drug that reduces histamine effects, a chemical substance that causes allergies like runny nose and skin rash. Together, it relieves the common cold symptoms.
Directions for Use
Storage
Side Effects of Nimesulide+pseudoephedrine+cetirizine
- Nausea
- Vomiting
- Diarrhea
- High blood pressure
- Dryness in mouth
- Fatigue
- Difficulty in sleeping
- Sleepiness
- Anxiety
- Nervousness
- Dizziness
- Restlessness
- Headache
- Increased heart rate
- Increased liver enzymes.
In-Depth Precautions and Warning
Drug Warnings
Let your doctor know if you have any allergic reactions to medicines. Please inform your doctor before starting Nimesulide+pseudoephedrine+cetirizine if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery, heart disease, severe renal/hepatic impairment, or history of allergy to any painkillers as Nimesulide+pseudoephedrine+cetirizine may worsen your condition. It is mandatory to inform your doctor if you have prostate enlargement, urinary retention, diabetes, and eye disorders like cataracts and glaucoma before taking Nimesulide+pseudoephedrine+cetirizine. Nimesulide+pseudoephedrine+cetirizine contains Nimesulide which causes an increased chance of problems with joints and tissues around joints in children under 18 years. So, let your doctor know if your children have any joint problems during or after treatment with Nimesulide+pseudoephedrine+cetirizine. You get severe sunburn or blisters on your skin as an intake of Nimesulide+pseudoephedrine+cetirizine may increase the skin's sensitivity. Please check with your doctor if you are pregnant or breastfeeding. Avoid consuming alcohol with Nimesulide+pseudoephedrine+cetirizine as it could lead to increased drowsiness or dizziness. Do not drive if you feel sleepy after taking Nimesulide+pseudoephedrine+cetirizine.
Drug Interactions
Drug-Drug Interactions: Nimesulide+pseudoephedrine+cetirizine is shown to interact with the antianxiety drug (alprazolam), blood thinners (warfarin), anti-arthritis or anti-cancer agents (methotrexate), antifungal (ketoconazole), cough suppressants (hydrocodone), anti-allergic drugs (diphenhydramine).
Drug-Food Interactions: Limit alcohol intake since it may worsen the side effects like dizziness, drowsiness, and difficulty concentrating. Nimesulide+pseudoephedrine+cetirizine contains nimesulide, therefore, do not take it with dairy products like milk, yogurt, or calcium-fortified juices.
Drug-Disease Interactions: Nimesulide+pseudoephedrine+cetirizine should be administered with caution in patients with heart, liver, kidney diseases, diabetes, and glaucoma.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionTaking Nimesulide+pseudoephedrine+cetirizine with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with Nimesulide+pseudoephedrine+cetirizine.
Pregnancy
unsafeNimesulide+pseudoephedrine+cetirizine contains nimesulide which is not recommended during pregnancy especially during the last 3 months of pregnancy may harm the unborn baby. There are limited studies on how Nimesulide+pseudoephedrine+cetirizine affects pregnancy. However, the animal studies of Pseudoephedrine in Nimesulide+pseudoephedrine+cetirizine showed harmful effects on the developing baby.
Breast Feeding
unsafeUse of Nimesulide+pseudoephedrine+cetirizine during breastfeeding is not recommended as it may pass through the milk and harm the baby.
Driving
cautionAfter taking Nimesulide+pseudoephedrine+cetirizine, you may notice dizziness, sleepiness, drowsiness. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.
Liver
cautionNimesulide+pseudoephedrine+cetirizine can cause hepatotoxicity (liver damage). So, it should not be taken with caution in liver disease/impairment only when prescribed by a doctor.
Kidney
cautionCetirizine in Nimesulide+pseudoephedrine+cetirizine is contraindicated in patients undergoing dialysis treatment. Please consult your doctor before taking Nimesulide+pseudoephedrine+cetirizine in cases of renal impairment.
Children
cautionNimesulide+pseudoephedrine+cetirizine contains Nimesulide which is contraindicated in children below 12 years of age. It may cause kidney problems in children and adolescents who are dehydrated.
Habit Forming
Diet & Lifestyle Advise
- Take Nimesulide+pseudoephedrine+cetirizine as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal, or vitamin supplements without informing your pharmacist or doctor when you take Nimesulide+pseudoephedrine+cetirizine.
- Know your triggers like allergens, such as pollen, dust, and food items that make your asthma and other respiratory diseases severe.
- Quit smoking and avoid passive smoking. Smoking may reduce the effectiveness of the medicine.
- Drink warm fluids while you take Nimesulide+pseudoephedrine+cetirizine to help loosen congestion and lubricate the throat.
- Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
- Learning breathing exercises will help you move more air in and out of your lungs.
- Avoid alcohol consumption with Nimesulide+pseudoephedrine+cetirizine as it may cause tiredness, drowsiness, or lack of concentration.
Special Advise
- Regularly monitor your blood sugar levels while using Nimesulide+pseudoephedrine+cetirizine since decongestants like Pseudoephedrine can increase blood glucose levels.
- Consult your diabetologist if you have diabetes before using Nimesulide+pseudoephedrine+cetirizine so that your insulin or other diabetic medication can be adjusted accordingly to maintain your blood sugar levels.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by viruses, mainly 'rhinovirus' affecting your nose and throat (upper respiratory tract). Children younger than six years of age are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like dust, pollutants, etc. Symptoms of a common cold might include stuffy or runny nose, sore throat, cough, congestion, mild body pain or a mild headache, sneezing, low-grade fever, and feeling unwell (malaise).
FAQs
No, pseudoephedrine in Nimesulide+pseudoephedrine+cetirizine may increase the blood sugar/blood glucose levels. You are advised to monitor your blood glucose levels while taking Nimesulide+pseudoephedrine+cetirizine regularly. Inform your doctor if you have diabetes before consuming Nimesulide+pseudoephedrine+cetirizine.
Cetirizine in Nimesulide+pseudoephedrine+cetirizine is contraindicated in patients undergoing dialysis treatment. Thus, it is advisable do not to take Nimesulide+pseudoephedrine+cetirizine if you are undergoing dialysis treatment. Please consult your doctor before taking Nimesulide+pseudoephedrine+cetirizine in cases of renal impairment.
Nimesulide+pseudoephedrine+cetirizine is not recommended for use in patients with prostate enlargement since Pseudoephedrine present in Nimesulide+pseudoephedrine+cetirizine may cause or worsen urinary difficulty in patients with prostate enlargement. It is advised to consult your doctor before using Nimesulide+pseudoephedrine+cetirizine.
Nimesulide+pseudoephedrine+cetirizine contains nimesulide. This medicine is known to cause harm to the liver particularly in doses above the advised level. Also, avoid drinking alcohol while taking this Nimesulide+pseudoephedrine+cetirizine, as it may further enhance your risk of liver damage. Use of this Nimesulide+pseudoephedrine+cetirizine should preferably be avoided in patients with the underlying liver disease.
Yes, Nimesulide+pseudoephedrine+cetirizine may cause drowsiness. It is not necessary for everyone taking Nimesulide+pseudoephedrine+cetirizine to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Nimesulide+pseudoephedrine+cetirizine.
