PERINDOPRIL ERBUMINE
About
PERINDOPRIL ERBUMINE is an anti-hypertensive medication primarily used to treat high blood pressure and heart failure. It is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.
PERINDOPRIL ERBUMINE contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). PERINDOPRIL ERBUMINE relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body.
Take PERINDOPRIL ERBUMINE as prescribed. Your doctor will advise you on the dosage and duration based on your medical condition. In some cases, you may experience dizziness, headache, weakness, vomiting, and nausea. Most of these side effects of PERINDOPRIL ERBUMINE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine on your own, even if your blood pressure becomes normal; doing so may worsen your condition. Avoid taking PERINDOPRIL ERBUMINE if you are pregnant or breastfeeding. PERINDOPRIL ERBUMINE is not recommended for children below 18years. PERINDOPRIL ERBUMINE may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.
Uses of PERINDOPRIL ERBUMINE
Medicinal Benefits
PERINDOPRIL ERBUMINE is used to treat high blood pressure and heart failure. Additionally, it is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. PERINDOPRIL ERBUMINE contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). PERINDOPRIL ERBUMINE allows constricted blood vessels to relax and therefore helps lower high blood pressure.
Directions for Use
Storage
Side Effects of PERINDOPRIL ERBUMINE
- Cough
- Nausea
- Dizziness
- Headache
- Vision disturbances
- Ankle swelling
- Weakness
- Vomiting
In-Depth Precautions and Warning
Drug Warnings
Do not take PERINDOPRIL ERBUMINE if you are allergic to any of the contents, ACE inhibitors, if you are taking sacubitril, valsartan, or aliskiren. Inform your doctor if you have/had kidney problems, dialysis, heart problems, liver dysfunction, diabetes, dehydration, angioedema, collagen vascular disease, or primary aldosteronism. Consult your doctor if you develop signs of infection or jaundice. Avoid taking PERINDOPRIL ERBUMINE if you are pregnant or breastfeeding. PERINDOPRIL ERBUMINE is not recommended for children below 18years. PERINDOPRIL ERBUMINE may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.
Drug Interactions
Drug-Drug Interaction: PERINDOPRIL ERBUMINE may interact with medication used for heart failure, high blood pressure (nitroglycerin, aliskiren, losartan, valsartan, olmesartan, candesartan, captopril, enalapril), epilepsy and anxiety medications (pregabalin), diuretics (hydrochlorothiazide, furosemide, bumetanide, chlorthalidone, and indapamide), NSAIDs (naproxen, ibuprofen, indomethacin, celecoxib), narcotic analgesics (codeine) and medication used for mania and depression (lithium).
Drug-Food Interaction: Avoid intake of high potassium and sodium intake. Including these in your diet might increase the level of potassium in your blood (hyperkalemia). Besides this, do not use salt substitutes or potassium supplements while taking PERINDOPRIL ERBUMINE.
Drug-Disease Interaction: Inform your doctor if you have/had angioedema (swelling), bone marrow suppression, congestive heart failure, hemodialysis (A medical procedure to remove fluid and waste products from the blood and to correct electrolyte imbalances), hyperkalemia (high potassium level), low blood pressure (hypotension), liver disease, and kidney dysfunction.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAlcohol may enhance the hypotensive (low blood pressure) effect of PERINDOPRIL ERBUMINE. It may also cause increased dizziness. For better advice, you should consult your doctor if you can take PERINDOPRIL ERBUMINE with alcohol.
Pregnancy
unsafeAvoid taking PERINDOPRIL ERBUMINE if you are pregnant, especially if you are more than 3months pregnant as it may cause harm to the developing fetus. Consult your doctor if you are pregnant or planning for pregnancy.
Breast Feeding
unsafeUse of PERINDOPRIL ERBUMINE is not recommended during the breastfeeding.
Driving
cautionPERINDOPRIL ERBUMINE may cause blurry vision, dizziness or weakness. Drive or operate machinery only if you are alert.
Liver
cautionRare elevation in liver enzymes (like bilirubin) has been observed while taking PERINDOPRIL ERBUMINE, so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.
Kidney
cautionPERINDOPRIL ERBUMINE to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. PERINDOPRIL ERBUMINE should be given with precaution in hemodialysis condition.
Children
unsafeThe safety and effectiveness of PERINDOPRIL ERBUMINE in children below 18years have not been established.
Habit Forming
Diet & Lifestyle Advise
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
- Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
- Limit intake of sodium chloride (table salt) in your daily diet.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
Special Advise
- Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
- Inform your doctor if you are due to undergo any surgery, LDL apheresis (removal of cholesterol from blood), or desensitisation treatment.
- Regular kidney function, blood pressure, and electrolyte level monitoring are advised.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition in which the blood exerts increased pressure on the artery walls. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. High blood pressure (hypertension) can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked), brain damage (stroke), and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
PERINDOPRIL ERBUMINE relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body.
It is advised to continue taking PERINDOPRIL ERBUMINE even after your blood pressure is under control or becomes normal as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.
PERINDOPRIL ERBUMINE might alter potassium levels. Therefore inform your doctor if you are taking food rich in potassium, potassium-containing salt substitutes or over-the-counter potassium supplements.
Light-headedness could be a side-effect of PERINDOPRIL ERBUMINE. It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking PERINDOPRIL ERBUMINE are advised to regularly monitor their blood pressure levels to avoid unpleasant events.
Inform your doctor if you are diabetic as PERINDOPRIL ERBUMINE may cause hypoglycaemia (low blood glucose levels). Regular monitoring of blood sugar levels is advised.
