Chloramphenicol+dexamethasone+polymyxin B
About
Polymyxin B+chloramphenicol+dexamethasone belongs to the class of combination medications called ‘antibiotics' and 'steroids' used for the treatment of bacterial eye infections and ear infections. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Polymyxin B+chloramphenicol+dexamethasone does not work against infections caused by viruses and fungi.
Polymyxin B+chloramphenicol+dexamethasone is a combination of Chloramphenicol, Dexamethasone, and Polymyxin B. Chloramphenicol is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal that works by killing the bacterial cell by preventing bacterial cell walls' formation essential for survival. Together Polymyxin B+chloramphenicol+dexamethasone prevent the spread of eye and ear infections caused by a wide range of gram-negative bacteria causing eye/ear infections.
You should use this medicine as prescribed by your doctor. When used in the eyes, the common side effects are eye discomfort, eye irritation, and a burning sensation in the eye. When used as ear drops, the side effects include mild irritation and temporary ear discomfort. Most of these side effects of Polymyxin B+chloramphenicol+dexamethasone do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Polymyxin B+chloramphenicol+dexamethasone or any other medicines, please tell your doctor. Polymyxin B+chloramphenicol+dexamethasone should be used with caution in children. You are advised to consult a doctor if you are pregnant or breastfeeding. You are recommended not to use contact lenses during the course of Polymyxin B+chloramphenicol+dexamethasone as it may worsen the infection. You are advised to maintain a 10 minutes time gap between using Polymyxin B+chloramphenicol+dexamethasone and other eye drops. Please do not touch the container tip to the eye, eyelids, or surrounding areas as it may contaminate Polymyxin B+chloramphenicol+dexamethasone and cause eye infections. Before using Polymyxin B+chloramphenicol+dexamethasone, inform your doctor if you have fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis. Do not use Polymyxin B+chloramphenicol+dexamethasone if you have tuberculosis, damaged cornea, ulceration, lesions with missing skin that cover the eye or ear, and increased pressure inside the eye.
Uses of Chloramphenicol+dexamethasone+polymyxin B
Medicinal Benefits
Polymyxin B+chloramphenicol+dexamethasone is a combination of Chloramphenicol, Dexamethasone, and Polymyxin B belongs to the class of combination medications called ‘antibiotics' and 'steroids' used for the treatment of bacterial eye infections and ear infections. Chloramphenicol is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal, killing the bacterial cell by preventing bacterial cell walls' formation essential for survival. Together Polymyxin B+chloramphenicol+dexamethasone prevent the spread of eye and ear infections caused by a wide range of gram-negative bacteria causing eye/ear infections.
Directions for Use
Storage
Side Effects of Chloramphenicol+dexamethasone+polymyxin B
Eye drops:
- Eye discomfort
- Eye irritation
- Burning sensation in the eye
Ear drops:
- Mild irritation
- Temporary ear discomfort
In-Depth Precautions and Warning
Drug Warnings
Please tell your doctor if you are allergic to Polymyxin B+chloramphenicol+dexamethasone or any other medicines. Polymyxin B+chloramphenicol+dexamethasone should be used with caution in children. You are advised to consult a doctor if you are pregnant or breastfeeding. You are recommended not to use contact lenses during the course of Polymyxin B+chloramphenicol+dexamethasone as it may worsen the infection. You are advised to maintain a 10 minutes time gap between using Polymyxin B+chloramphenicol+dexamethasone and other eye drops. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Polymyxin B+chloramphenicol+dexamethasone and cause eye infections. Before using Polymyxin B+chloramphenicol+dexamethasone, inform your doctor if you have fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis. Do not use Polymyxin B+chloramphenicol+dexamethasone if you have tuberculosis, damaged cornea, ulceration, lesions with missing skin that cover the eye or ear and increased pressure inside the eye.
Drug Interactions
Drug-Drug Interactions: Polymyxin B+chloramphenicol+dexamethasone may interact with an anti-cancer agent (methotrexate), immune suppressant (azathioprine), antiviral drug (ritonavir), and a medication used to treat HIV (cobicistat).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Polymyxin B+chloramphenicol+dexamethasone should not be used in patients with fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis, tuberculosis, damaged cornea, ulceration, and glaucoma (increased pressure inside the eye).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol may affect your ability to fight infections. So, it is recommended to avoid alcohol consumption until your condition improves.
Pregnancy
unsafeThe consequences of Polymyxin B+chloramphenicol+dexamethasone during pregnancy are unknown; therefore, do not use it unless your doctor deems it necessary. Ask your doctor for advice before using this medication if you are pregnant, suspect you may be pregnant or are planning a pregnancy.
Breast Feeding
cautionThe consequences of Polymyxin B+chloramphenicol+dexamethasone during breastfeeding are unknown; therefore, do not use it unless your doctor deems it necessary. Ask your doctor for advice before using this medication if you are breastfeeding.
Driving
cautionPolymyxin B+chloramphenicol+dexamethasone may affect your vision. So, do not drive or operate heavy machinery until your vision clears after using Polymyxin B+chloramphenicol+dexamethasone.
Liver
safe if prescribedPolymyxin B+chloramphenicol+dexamethasone can be used for treating eye/ear infections in patients with liver diseases.
Kidney
safe if prescribedPolymyxin B+chloramphenicol+dexamethasone can be used for treating eye/ear infections in patients with kidney problems.
Children
safe if prescribedPolymyxin B+chloramphenicol+dexamethasone can be used with caution in children to treat middle and outer ear infections. Use it only if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Sleep for at least six to eight hours to rejuvenate your eyes naturally.
- Wash your eyes with clean water at least two to three times a day
- Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
- Keep your ear clean and dry.
- Avoid alcoholic beverages as they can make you dehydrated and affect your sleep. This effect can also affect your body’s ability to fight off infections.
Special Advise
- Do not wear contact lenses while using Polymyxin B+chloramphenicol+dexamethasone eye drops.
- Avoid getting water in your ears while bathing, showering, or swimming while treating an ear infection.
- Avoid prolonged exposure to sunlight while using Polymyxin B+chloramphenicol+dexamethasone as it may cause increased photosensitivity (sensitivity to light).
Patients Concern
Disease/Condition Glossary
Conjunctivitis: The inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that is spread by secretions of the eye. Symptoms include redness, itch, and discharge or crusting around the eye.
Bacterial ear infection: The outer, middle, and inner regions of the ear are all affected when a bacterium invades the ear, which causes bacterial ear infection. Due to inflammation and fluid buildup in the middle ear, ear infections can be uncomfortable. Short-term to long-term ear infections can be acute or chronic in nature. The term 'middle ear infection' also applies to otitis media.
FAQs
Polymyxin B+chloramphenicol+dexamethasone is a combination of three medicines: Chloramphenicol, Dexamethasone and Polymyxin B. Chloramphenicol is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal that works by killing the bacterial cell by preventing bacterial cell walls' formation essential for survival. Together Polymyxin B+chloramphenicol+dexamethasone prevent the spread of eye and ear infections caused by a wide range of gram-negative bacteria causing eye/ear infections.
You are not recommended to wear contact lenses during the entire course of Polymyxin B+chloramphenicol+dexamethasone as it may worsen the infection. Therefore, you are advised to remove contact lenses before using Polymyxin B+chloramphenicol+dexamethasone and reinsert them after 24 hours of finishing the course of Polymyxin B+chloramphenicol+dexamethasone.
You are recommended to maintain a minimum of 10 minutes time gap between using Polymyxin B+chloramphenicol+dexamethasone and other eye drops and administering eye ointments in the last.
