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Polymyxin B+neomycin+hydrocortisone

About

Polymyxin B+neomycin+hydrocortisone belongs to two classes of medications: antibiotics and steroids. It is primarily used to treat bacterial ear infections. An ear infection occurs when bacteria invade the middle or outer ear, causing pain and inflammation. On the other hand, Polymyxin B+neomycin+hydrocortisone can also use to treat ear infections as a complication after ear surgery (e.g., mastoidectomy, fenestration).

Polymyxin B+neomycin+hydrocortisone is a combination medicine that contains Neomycin, Polymyxin B and Hydrocortisone. Neomycin and polymyxin B belong to the class of medicines known as antibiotics; they work by killing bacteria or preventing their growth. Hydrocortisone is a steroid medicine used to relieve the redness, itching, and swelling caused by ear infections. Together Polymyxin B+neomycin+hydrocortisone reduces redness, irritation, and discomfort of certain ear problems.

Polymyxin B+neomycin+hydrocortisone is only for otic (ear) use. Depending on your medical condition, you are advised to use Polymyxin B+neomycin+hydrocortisone for as long as your doctor prescribes it. In some cases, you may experience common side effects, such as a burning sensation, irritation, itching and redness at the application site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of the ingredients in the Polymyxin B+neomycin+hydrocortisone. Before using Polymyxin B+neomycin+hydrocortisone, notify your doctor if you have hearing problems (ototoxicity), a perforated eardrum or chronic otitis media. Consult your doctor if you are pregnant or breastfeeding. Polymyxin B+neomycin+hydrocortisone should be used in children only when advised by a doctor. Before taking Polymyxin B+neomycin+hydrocortisone, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects and interactions.

Uses of Polymyxin B+neomycin+hydrocortisone

Bacterial ear infections

Medicinal Benefits

Polymyxin B+neomycin+hydrocortisone is a combination medicine that contains Neomycin, Polymyxin B and Hydrocortisone. Neomycin and polymyxin B belong to the class of medicines known as antibiotics; they work by killing bacteria or preventing their growth. Hydrocortisone is a steroid medicine used to relieve the redness, itching, and swelling caused by ear infections. Together Polymyxin B+neomycin+hydrocortisone reduces redness, irritation, and discomfort of certain ear problems.  Besides this, it can also be used to treat ear infections as a complication after ear surgery (e.g., mastoidectomy, fenestration).

Directions for Use

Lie down with the affected ear facing upwards. Hold the dropper over the ear and instil the prescribed number of drops. Continue to lie on your side for two minutes to allow the drops to reach the base of the ear canal. Repeat the procedure for the other ear if needed. Avoid contamination by not touching the dropper to the ear or surrounding areas.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Polymyxin B+neomycin+hydrocortisone

  • Burning sensation
  • Irritation
  • Itching
  • Redness
  • Rash
  • Red, itchy, dry, scaly skin at the affected site 
  • Abnormal sensation in the ear

In-Depth Precautions and Warning

Drug Warnings

Do not use Polymyxin B+neomycin+hydrocortisone if you are allergic to any of its components. Polymyxin B+neomycin+hydrocortisone is only to be used in the ears. Polymyxin B+neomycin+hydrocortisone should never be injected or used orally. Avoid contact with the Polymyxin B+neomycin+hydrocortisone with your nose, mouth, or eyes. If Polymyxin B+neomycin+hydrocortisone comes into contact with these areas accidentally, thoroughly rinse it with water. Do not use Polymyxin B+neomycin+hydrocortisone without consulting the doctor if you are pregnant, planning to become pregnant, or breastfeeding. Before taking Polymyxin B+neomycin+hydrocortisone, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects and interactions. Polymyxin B+neomycin+hydrocortisone should not be used longer than your doctor prescribes. Contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

Drug Interactions

Drug-Drug Interactions: Relevant interactions could not be found/established. However, do not use other ear products without talking to your doctor or health care professional.

Drug-Food Interactions: Relevant interactions could not be found/established.

Drug-Disease Interactions:  Relevant interactions could not be found/established.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    No interaction was found/established. However, It is best to avoid alcohol consumption while using medication.

  • Safety Warning

    Pregnancy

    caution

    If you are planning to become pregnant or are already pregnant, please inform your doctor. Your doctor will prescribe if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    Inform your doctor if you are breastfeeding. Your doctor will prescribe if the benefits outweigh the risks.

  • Safety Warning

    Driving

    safe if prescribed

    Polymyxin B+neomycin+hydrocortisone has no or negligible influence on the ability to drive or use machines.

  • Safety Warning

    Liver

    caution

    Limited information about the usage of Polymyxin B+neomycin+hydrocortisone in patients with liver disease is available. Please inform your physician if you have had a liver impairment/disorder history. Your doctor will prescribe if the benefits outweigh the risks.

  • Safety Warning

    Kidney

    caution

    Limited information about the usage of Polymyxin B+neomycin+hydrocortisone in patients with kidney disease is available. Please inform your physician if you have had a kidney impairment/disorder history. Your doctor will prescribe if the benefits outweigh the risks.

  • Safety Warning

    Children

    caution

    Polymyxin B+neomycin+hydrocortisone should not be used in children unless prescribed by the doctor.

Habit Forming

No

Diet & Lifestyle Advise

  • Consult an ENT on a regular basis to ensure early detection of any ear problems.
  • Avoid consuming foods you are allergic to, as it can cause the body to produce excess mucus, resulting in ear inflammation.
  • Avoid getting shampoo, soap, or water into your ears, as this can cause itching.
  • Poking or scratching the ear can cause damage to the ear canal, resulting in inflammation. 
  • Using cotton swabs, bobby pins, or other objects to remove earwax may push wax deeper into the ear, causing ear damage.
  • Never put cold water in your ear, and avoid spraying liquids into your ear with force.

Patients Concern

Disease/Condition Glossary

Bacterial ear infections: An ear infection occurs when the bacteria affect the middle or outer ear, leading to pain and inflammation. An ear infection occurs when the Eustachian tubes (small tubes that run from each ear to the back of the throat) become blocked or swollen. Ear infections can be painful due to inflammation and fluid build-up. Symptoms include pain or discomfort inside the ear, pus or fluid-like drainage from the ear, feeling of pressure inside the ear, and loss of hearing.

FAQs

Polymyxin B+neomycin+hydrocortisone is a combination medicine that contains Neomycin, Polymyxin B and Hydrocortisone. Neomycin and polymyxin B belong to the class of medicines known as antibiotics; they work by killing bacteria or preventing their growth. Hydrocortisone is a steroid medicine used to relieve the redness, itching, and swelling caused by ear infections. Together Polymyxin B+neomycin+hydrocortisone reduces redness, irritation, and discomfort of certain ear problems.

Hydrocortisone is a corticosteroid (steroid) medication. It reduces discomfort, itching, and swelling (inflammation) caused by ear infections by reducing your body's immunological reaction.

Polymyxin B+neomycin+hydrocortisone should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using Polymyxin B+neomycin+hydrocortisone for 2-4 weeks, consult your doctor.

Polymyxin B+neomycin+hydrocortisone does not help in treating eye infections. Polymyxin B+neomycin+hydrocortisone is used to treat ear infections caused by bacteria.

Please do not stop using Polymyxin B+neomycin+hydrocortisone without consulting your doctor on your own. Continue using Polymyxin B+neomycin+hydrocortisone for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Polymyxin B+neomycin+hydrocortisone.

Available Medicines for

Polymyxin B+neomycin+hydrocortisone

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