Pregabalin+mecobalamin+folic Acid+pyridoxine
About
Pregabalin+mecobalamin+folic Acid+pyridoxine is a combination of medicine that belongs to the class of medicines known as ‘anticonvulsant'. It is primarily used for the treatment of neuropathic pain. Neuropathic pain is a chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash) or spinal cord injury, injuries to tissue, muscles or joints.
Pregabalin+mecobalamin+folic Acid+pyridoxine contains four medicines namely Pregabalin, Mecobalamin, Folic acid and Pyridoxine. Pregabalin works by calming the damaged or overactive nerves in your body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body. Mecobalamin and pyridoxine both are forms of vitamin B and helps in the reconstruction and protection of damaged nerve cells by producing a substance called myelin. A folic acid is also a form of vitamin B that helps in providing essential nutrients to the nerves. Together, Pregabalin+mecobalamin+folic Acid+pyridoxine helps in providing relief from neuropathic (damage nerve) pain.
Take Pregabalin+mecobalamin+folic Acid+pyridoxine as prescribed by your doctor. You are advised to take Pregabalin+mecobalamin+folic Acid+pyridoxine for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience dizziness, tiredness, sleepiness and uncoordinated body movements. Most of these side effects of Pregabalin+mecobalamin+folic Acid+pyridoxine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
To treat your condition effectually, continue taking Pregabalin+mecobalamin+folic Acid+pyridoxine for as long as your doctor has prescribed. Please do not stop taking Pregabalin+mecobalamin+folic Acid+pyridoxine without consulting your doctor as it could cause withdrawal symptoms. Pregabalin+mecobalamin+folic Acid+pyridoxine should not be given to children as safety and effectiveness have not been established. Do not take Pregabalin+mecobalamin+folic Acid+pyridoxine if you are pregnant or breastfeeding unless prescribed by the doctor. Pregabalin+mecobalamin+folic Acid+pyridoxine causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Pregabalin+mecobalamin+folic Acid+pyridoxine as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Pregabalin+mecobalamin+folic Acid+pyridoxine
Medicinal Benefits
Pregabalin+mecobalamin+folic Acid+pyridoxine is a combination of four medicines namely Pregabalin, Mecobalamin, Folic acid and Pyridoxine. Pregabalin is an anti-convulsant that affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels, this helps relieve nerve pain and lowers the risk of seizures. Mecobalamin and pyridoxine both are forms of vitamin B and helps in the reconstruction and protection of damaged nerve cells by producing a substance called myelin. Folic acid is a vitamin that helps in providing essential nutrients to the nerves. Together, Pregabalin+mecobalamin+folic Acid+pyridoxine helps in providing relief from neuropathic pain. Additionally, Pregabalin+mecobalamin+folic Acid+pyridoxine may also be used to treat diabetic neuropathy, fibromyalgia (muscle pain) and postherpetic neuralgia (burning pain in nerves and skin).
Directions for Use
Storage
Side Effects of Pregabalin+mecobalamin+folic Acid+pyridoxine
- Dizziness
- Tiredness
- Sleepiness
- Nausea and vomiting
- Stomach discomfort and pain
- Uncoordinated body movements
- Swelling of face, lips, eyelids, tongue, hands and feet
- Blurred or double vision
- Unusual tiredness and weakness
- Dry mouth
- Fever
In-Depth Precautions and Warning
Drug Warnings
Do not take Pregabalin+mecobalamin+folic Acid+pyridoxine if you are allergic to any of its contents. Inform your doctor before taking Pregabalin+mecobalamin+folic Acid+pyridoxine if you have or had heart problems or bipolar syndrome. Please do not stop taking Pregabalin+mecobalamin+folic Acid+pyridoxine without consulting your doctor as it could cause withdrawal symptoms. Do not take Pregabalin+mecobalamin+folic Acid+pyridoxine if you are pregnant or breastfeeding unless prescribed by the doctor. Pregabalin+mecobalamin+folic Acid+pyridoxine causes drowsiness and dizziness, so drive only if you are alert. Pregabalin+mecobalamin+folic Acid+pyridoxine should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabalin+mecobalamin+folic Acid+pyridoxine as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Drug Interactions
Drug-Drug Interactions: Pregabalin+mecobalamin+folic Acid+pyridoxine may have interaction with other anti-convulsant medications (gabapentin, phenobarbital, phenytoin), antidepressant medications (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline), pain killer medications (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol), anti-anxiety medications (diazepam, alprazolam), anti-diabetic medications (metformin), immunosuppressant medications (methotrexate), anti-rheumatoid medications (sulfasalazine), antibiotic medications (neomycin, chloramphenicol), anti-cancer medications (altretamine), anti-Parkinson’s medications (levodopa).
Drug-Food Interactions: Avoid consumption of alcohol while taking Pregabalin+mecobalamin+folic Acid+pyridoxine as it might cause increased dizziness and sleepiness.
Drug- Disease Interactions: Pregabalin+mecobalamin+folic Acid+pyridoxine may have interactions with disease conditions such as suicidal tendency, heart problems, liver/kidney impairment angioedema, peripheral edema, malabsorption and anemia.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Pregabalin+mecobalamin+folic Acid+pyridoxine as it may increase dizziness and sleepiness.
Pregnancy
cautionAvoid taking Pregabalin+mecobalamin+folic Acid+pyridoxine if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor before taking Pregabalin+mecobalamin+folic Acid+pyridoxine, your doctor will decide whether Pregabalin+mecobalamin+folic Acid+pyridoxine can be taken by breastfeeding mothers or not.
Driving
cautionPregabalin+mecobalamin+folic Acid+pyridoxine causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
cautionPregabalin+mecobalamin+folic Acid+pyridoxine should not be given to children as the safety and efficacy have not been established.
Habit Forming
Diet & Lifestyle Advise
- Include food rich in vitamin B and D in your diet.
- Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
- Exercising regularly helps in improving overall health and combating pain.
- Rest well, get plenty of sleep.
- Try taking a warm bath as it can be soothing.
- Avoid smoking and alcohol consumption.
- Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
- Acupuncture can be helpful by stimulating pressure points.
- Using essential oils for massages can help increase circulation.
Special Advise
- Consult your doctor immediately if you observe any changes in your behaviour, physically, mentally or psychologically.
- You are recommended not to stop Pregabalin+mecobalamin+folic Acid+pyridoxine suddenly, without consulting with your doctor.
- Inform your doctor about any addictions as Pregabalin+mecobalamin+folic Acid+pyridoxine may cause dependence, especially in patients who are chronic alcohol users or in patients who have used other recreational drugs in the past. Report the past use of alcohol or other drugs to the doctor before receiving Pregabalin+mecobalamin+folic Acid+pyridoxine.
Patients Concern
Disease/Condition Glossary
Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).
FAQs
Pregabalin+mecobalamin+folic Acid+pyridoxine is a combination of four medicines namely Pregabalin, Mecobalamin, Folic acid, and Pyridoxine. Pregabalin works by binding to the specific site on voltage-gated calcium channels, this helps in relieving nerve pain and lowers the risk of seizures. Mecobalamin and pyridoxine both are forms of vitamin B and helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Folic acid helps in providing essential nutrients to the nerves. Together, Pregabalin+mecobalamin+folic Acid+pyridoxine helps in providing relief from neuropathic pain.
Pregabalin+mecobalamin+folic Acid+pyridoxine is used to treat diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly causes pain in the legs and feet.
Pregabalin+mecobalamin+folic Acid+pyridoxine may be used to treat fibromyalgia. Fibromyalgia is a condition that is characterized by musculoskeletal pain, tenderness, fatigue, sleep and mood issues.
Do not discontinue Pregabalin+mecobalamin+folic Acid+pyridoxine without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Pregabalin+mecobalamin+folic Acid+pyridoxine for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregabalin+mecobalamin+folic Acid+pyridoxine, your doctor will reduce the dose gradually.
No, you are not recommended to take Pregabalin+mecobalamin+folic Acid+pyridoxine with tramadol as co-administration of these medicines may cause breathing problems, drowsiness and even lead to a stage of coma. So, before using Pregabalin+mecobalamin+folic Acid+pyridoxine with pain killers like oxycodone or any other opioids analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
