Rosuvastatin+calcitriol
About Rosuvastatin+calcitriol
Rosuvastatin+calcitriol belongs to the class of ‘cholesterol-lowering agents’ primarily used to lower abnormally elevated bad cholesterol or fat levels like low-density lipoprotein (LDL) and triglycerides (TG) and increases good cholesterol levels (high-density lipoprotein or HDL) in the bloodstream. Hyperlipidaemia or dyslipidaemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. This condition can clog the blood vessels and leads to coronary heart diseases, like stroke and heart attack.
Rosuvastatin+calcitriol is composed of two medicines, namely: Rosuvastatin and Calcitriol (Vitamin D3). Rosuvastatin belongs to drugs known as antilipemic agents (cholesterol-lowering)/statins or HMG-CoA reductase inhibitors. It works by blocking liver enzymes, causing the liver to make less cholesterol. Rosuvastatin lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Calcitriol is a synthetic version of Vitamin D3 that helps relieve musculoskeletal problems, as the main side effect caused by Rosuvastatin.
Take Rosuvastatin+calcitriol as prescribed by your doctor. Like every medicine, Rosuvastatin+calcitriol also has common side effects that include muscle pain, weakness, headache, constipation, dizziness and stomach pain. These side effects do not occur in everyone using Rosuvastatin+calcitriol and may vary individually. If these side effects occur, they resolve gradually over time and do not usually require medical attention. However, if you notice any side effects that are not manageable, it is advised to consult your doctor.
Try not to stop taking this medicine of your own. Let your doctor know if you have any kidney, liver or heart diseases, diabetes, lung problems, thyroid disease, alcohol use, muscle pain and brain disorders before starting Rosuvastatin+calcitriol. Rosuvastatin+calcitriol is not indicated for use during pregnancy and breastfeeding. Please avoid or limit alcohol intake since it may lead to increased dizziness while using Rosuvastatin+calcitriol. Rosuvastatin+calcitriol is recommended for use in children older than six years of age.
Uses of Rosuvastatin+calcitriol
Medicinal Benefits
Rosuvastatin+calcitriol is used to treat hyperlipidaemia or dyslipidaemia. It is composed of Rosuvastatin and Calcitriol. Rosuvastatin is a cholesterol-lowering agent or HMG-CoA reductase inhibitor. It works by blocking liver enzymes, causing the liver to make less cholesterol. It also lowers the bad cholesterol levels and increases good cholesterol levels in the blood. Rosuvastatin reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). Calcitriol is a synthetic version of Vitamin D3. It raises the Vitamin D levels and thereby increases calcium levels in the blood. Calcitriol helps in relieving musculoskeletal pain, a side effect caused by Rosuvastatin.
Directions for Use
Storage
Side Effects of Rosuvastatin+calcitriol
- Muscle pain
- Weakness
- Headache
- Constipation
- Dizziness
- Stomach pain
Drug Warnings
Before taking Rosuvastatin+calcitriol, let your doctor know if you have a history of kidney, liver or heart diseases, diabetes, lung problems, thyroid disease, alcohol use, muscle pain and brain disorders. Avoid using other over the counter medications, herbal or vitamin supplements without medical advice. Rosuvastatin+calcitriol may have harmful effects on the baby when a pregnant mother uses it. Rosuvastatin+calcitriol can pass into the breast milk and may affect the breastfed infants. Hence, the use of Rosuvastatin+calcitriol is contraindicated during pregnancy and breastfeeding. Please avoid or limit alcohol intake since it may lead to increased dizziness while using Rosuvastatin+calcitriol. Rosuvastatin+calcitriol is recommended for use in children older than 6 years of age. Higher doses of Rosuvastatin+calcitriol are not indicated for patients younger than 18 years of age.
Drug Interactions
Drug-Drug Interaction: Rosuvastatin+calcitriol may interact with other cholesterol-lowering drugs (Gemfibrozil, fenofibrate, ezetimibe), blood thinners (warfarin, clopidogrel), blood-related drugs (fostamatinib), antibiotics (erythromycin, fusidic acid), antiviral drugs (ritonavir, lopinavir, atazanavir, ombitasvir, paritaprevir, dasabuvir, velpatasvir, grazoprevir, elbasvir, glecaprevir, pibrentasvir), anti-cancer medicines (regorafenib), immunosuppressants (cyclosporine), antacids and oral contraceptives.
Drug-Food Interaction: Avoid fatty foods to help control your cholesterol and triglyceride levels.
Drug-Disease Interaction: Rosuvastatin+calcitriol should be used with caution if you have kidney, liver or heart diseases, diabetes, lung problems, thyroid disease, alcohol use, muscle pain and brain disorders.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is recommended to avoid or limit the intake of alcohol while using Rosuvastatin+calcitriol.
Pregnancy
unsafeRosuvastatin+calcitriol is a pregnancy X category medicine, so it is unsafe and not recommended during pregnancy. It has harmful effects on the foetus. If the patient becomes pregnant while using Rosuvastatin+calcitriol, please discontinue immediately and you should be aware of the potential risks to the foetus. Please consult your doctor if you are planning to conceive or already pregnant before starting Rosuvastatin+calcitriol.
Breast Feeding
unsafeRosuvastatin+calcitriol is not recommended for use if you are lactating, since Rosuvastatin+calcitriol passes through the breast milk and may affect breastfed infants.
Driving
cautionDo not drive or operate machinery if you experience dizziness while using Rosuvastatin+calcitriol. Please seek medical attention if the symptom persists longer.
Liver
cautionLet your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Rosuvastatin+calcitriol.
Kidney
cautionLet your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Rosuvastatin+calcitriol.
Children
cautionRosuvastatin+calcitriol is recommended for use in children older than six years of age. Higher doses of Rosuvastatin+calcitriol are not indicated for patients younger than 18 years of age and used only when prescribed by a child specialist.
Habit Forming
Diet & Lifestyle Advise
- Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Rosuvastatin+calcitriol.
- Low cholesterol diet and regular exercise regime are found to complement treatment with Rosuvastatin+calcitriol effectively.
- Keep your cholesterol and triglyceride levels under control.
- Eat at regular intervals and maintain a healthy diet that includes fresh fruits, vegetables.
- High-fat meal should be avoided as it may further increase the risk of heart attack and instead eat heart-healthy foods.
- Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
- Keep a check on your weight and exercise regularly to keep your heart healthy.
- Your doctor also guides you on noticing and managing the early symptoms of detecting heart diseases.
Special Advise
- Close monitoring of your heart like the ECG test is required every month.
- Lipid profile test consisting of HDL, LDL, TG, VLDL and TC is required every month to monitor cholesterol level.
Patients Concern
Disease/Condition Glossary
Hyperlipidaemia or dyslipidaemia: It occurs when there is an excess of harmful cholesterol (LDL) and a low level of good cholesterol (HDL) in the bloodstream. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol.
FAQs
Rosuvastatin+calcitriol lowers the bad cholesterol levels and increases good cholesterol levels in the blood, thus preventing high-cholesterol associated conditions like heart attack and stroke.
Let your doctor know if you have any kidney, liver or heart diseases, diabetes, lung problems, thyroid disease, alcohol use, muscle pain and brain disorders before taking Rosuvastatin+calcitriol. Please inform your doctor if you have any other medical issues.
Rosuvastatin+calcitriol can cause dizziness as one of its side effects. Please consult your doctor if you feel dizzy for a longer time. To reduce dizziness and light-headedness symptoms, it is advised to get up slowly when you rise from a sitting or lying position. Avoid driving or operating machinery during episodes of dizziness.
Antacids containing aluminium or magnesium may interfere with the absorption of Rosuvastatin+calcitriol. Hence it is advised to take antacids at least two hours after taking Rosuvastatin+calcitriol.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Yes, prolonged use of statin present in Rosuvastatin+calcitriol may cause muscle pain or weakness like rhabdomyolysis and myasthenia gravis. So, if you experience any sign of muscle pain or weakness, immediately contact a doctor.
