TERIZIDONE
About
TERIZIDONE belongs to the group of 'anti-tuberculosis drugs' primarily used to treat pulmonary (infection in the lungs) and extrapulmonary (infection at other sites of the body) tuberculosis. TERIZIDONE is a second-line drug and is used only when first-line drugs cannot be used. Tuberculosis is an infectious disease that primarily affects the lungs, but it can also spread to other body parts, such as kidneys, brain, spine, and bone marrow.
TERIZIDONE contains 'Terizidone' that belongs to the class of 'antimycobacterial.' It is bacteriostatic (stops bacterial growth) and works by preventing the cell wall synthesis in bacteria that cause tuberculosis.
Your doctor will decide the dose and duration of TERIZIDONE based on the severity of your disease. Common side effects of TERIZIDONE include confusion, difficulty in sleeping, headache, dizziness, slurred speech, depression, convulsions (fits), and tremor (shakiness). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
If you are known to be allergic to TERIZIDONE or its inactive components, please inform your doctor. Your doctor may suggest vitamin B6 and folic acid supplements while using TERIZIDONE. Inform your doctor beforehand if you have a history of liver or kidney diseases, heart problems, anxiety, depression, and fits. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Do not consume alcohol while using TERIZIDONE.
Uses of TERIZIDONE
Medicinal Benefits
TERIZIDONE contains 'Terizidone', which is used to treat multidrug-resistant and extensively-drug resistant tuberculosis. It is an antimycobacterial drug and has bacteriostatic action. It prevents the synthesis of the cell wall and interferes with the growth of bacteria that cause tuberculosis. TERIZIDONE is usually considered as a second-line drug and is used when the first-line drugs that treat tuberculosis are ineffective.
Directions for Use
Storage
Side Effects of TERIZIDONE
- Confusion
- Difficulty in sleeping
- Headache
- Dizziness
- Convulsions (fits)
- Slurred speech
- Depression
- Tremor (shakiness)
In-Depth Precautions and Warning
Drug Warnings
Let your doctor know if you are using any prescription and non-prescription medications, including other vitamins, before starting TERIZIDONE. Please tell your doctor if you are allergic to TERIZIDONE or its components. Brief your medical history to the doctor if you have any liver or kidney diseases, heart problems, anxiety, severe depression, frequent seizure (fits) episodes and alcohol use before starting TERIZIDONE. TERIZIDONE may lower vitamin B6 and folic acid levels; hence your doctor may advise supplements. Please let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoid alcohol intake while being treated with TERIZIDONE. Store TERIZIDONE below 25°C away from direct sunlight.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you take any depression medicines.
Drug-Food Interaction: Avoid alcohol and limit the use of cheese and fish while using TERIZIDONE.
Drug-Disease Interaction: Before using TERIZIDONE, let your doctor know if you have any liver or kidney diseases, heart problems, anxiety, severe depression, frequent seizure (fits) episodes, and alcohol use.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid alcohol consumption while taking TERIZIDONE. Please consult your doctor for more information.
Pregnancy
cautionThere is limited data on how TERIZIDONE affects pregnancy. Please consult your doctor before taking TERIZIDONE if you are pregnant or planning to conceive.
Breast Feeding
cautionIt is not known if TERIZIDONE is excreted into breast milk or not. Please consult your doctor before taking TERIZIDONE if you are a breastfeeding mother.
Driving
cautionTERIZIDONE may cause shakiness. Do not drive if you experience any symptoms that may affect your ability to drive or operate machinery.
Liver
cautionPlease consult your doctor since TERIZIDONE should be used with caution in patients with liver impairment/liver disease.
Kidney
cautionPlease consult your doctor since TERIZIDONE should be used with caution in patients with kidney impairment/kidney disease. Your doctor may adjust the dosage in case of renal dysfunction.
Children
cautionTERIZIDONE is recommended in children below 12 years of age only with a doctor's advice. The doctor will decide the dosage and duration based on the child's age and weight.
Habit Forming
Diet & Lifestyle Advise
- Foods rich in vitamin C, such as kiwi, broccoli and bell pepper, help improve the immune system.
- Avoid processed and fried foods.
- Warm ginger tea or warm soup can help in providing relief from cough.
- Avoid foods and drinks, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
- Quit smoking and avoid alcohol consumption.
Special Advise
- Let your doctor know that you are taking TERIZIDONE if you are undergoing any medical tests.
- Your doctor may advise for vitamin B6 and folic acid levels while undergoing treatment with TERIZIDONE since TERIZIDONE may lower vitamin B6 and folic acid levels.
Patients Concern
Disease/Condition Glossary
Tuberculosis (TB): Tuberculosis is an infectious disease that primarily affects the lungs, but it could also spread to other body parts such as kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can easily spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.
FAQs
TERIZIDONE contains 'Terizidone.' It is bacteriostatic and works by preventing the cell wall synthesis of the bacteria that causes tuberculosis.
TERIZIDONE should be used with caution under the doctor's supervision if you have a medical history of liver or kidney diseases, heart problems, anxiety, severe depression, frequent seizure (fits) episodes and allergic reactions. Please let your doctor know if you have any other medical problems before starting TERIZIDONE.
It is advised to take TERIZIDONE on an empty stomach for better results. However, if you take TERIZIDONE after food, avoid having high fatty meals. Please consult your doctor for more information.
Do not stop taking TERIZIDONE even if you feel better, as it may worsen your condition. You are recommended to complete the course as prescribed by your doctor. For the best advice, consult your doctor and do as recommended.
You may experience shakiness after using TERIZIDONE. Avoid driving in such cases until you are alert and focused. Consult your doctor if the condition persists longer.
Take the missed dose of TERIZIDONE as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
