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Thyroxine+pyridoxine+nicotinamide

About

Thyroxine+pyridoxine+nicotinamide is a combination medicine used to treat hypothyroidism. Hypothyroidism is a chronic condition in which the thyroid gland (located below the throat in the neck) cannot produce enough thyroid hormone. Thyroid hormones are composed of triiodothyronine (T3) and thyroxine (T4) which control the body's metabolism. In the condition of an underactive thyroid, the body's metabolism slows down, and the person feels less energetic. 

Thyroxine+pyridoxine+nicotinamide contains Thyroxine, Pyridoxine, and Nicotinamide. Thyroxine replaces the thyroid hormone that the thyroid gland is unable to produce. Pyridoxine/vitamin B6 helps in the utilisation of iodine, that is necessary for the synthesis of thyroxine hormone. Nicotinamide helps in keeping the body cells active. Pyridoxine and Nicotinamide help in providing essential nutrients. Together, Thyroxine+pyridoxine+nicotinamide helps in treating hypothyroidism.

You are advised to take Thyroxine+pyridoxine+nicotinamide for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as anxiety, vomiting, tremor, diarrhoea, palpitations, weight loss, and nervousness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Let your doctor know if you are allergic to any of the contents in Thyroxine+pyridoxine+nicotinamide. Consult your doctor before taking Thyroxine+pyridoxine+nicotinamide if you are pregnant. Thyroxine+pyridoxine+nicotinamide should be given to children only if prescribed by a doctor. Consult your doctor before consuming alcohol along with Thyroxine+pyridoxine+nicotinamide. Thyroxine+pyridoxine+nicotinamide does not help in treating obesity or weight problems. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Thyroxine+pyridoxine+nicotinamide

Hypothyroidism (underactive thyroid)

Medicinal Benefits

Thyroxine+pyridoxine+nicotinamide is a combination of three drugs, namely: Thyroxine, Pyridoxine and Nicotinamide. Thyroxine+pyridoxine+nicotinamide is used to treat hypothyroidism (underactive thyroid). Thyroxine is a synthetic thyroid hormone that is chemically similar to thyroxine produced by the thyroid gland. It replaces the thyroid hormone that the thyroid gland is unable to produce. Pyridoxine/vitamin B6 helps in the utilisation of iodine, that is necessary for the synthesis of thyroxine hormone. Nicotinamide helps in keeping the body cells active. Pyridoxine and Nicotinamide help in providing essential nutrients. Together, Thyroxine+pyridoxine+nicotinamide helps in treating hypothyroidism.

Directions for Use

Take Thyroxine+pyridoxine+nicotinamide on an empty stomach. Swallow Thyroxine+pyridoxine+nicotinamide as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Thyroxine+pyridoxine+nicotinamide

  • Anxiety
  • Vomiting
  • Tremor
  • Diarrhoea
  • Palpitations
  • Weight loss
  • Nervousness

In-Depth Precautions and Warning

Drug Warnings

Do not take Thyroxine+pyridoxine+nicotinamide if you are allergic to any of its contents. Talk to your doctor before taking Thyroxine+pyridoxine+nicotinamide if you have untreated/uncontrolled adrenal gland disorder, thyrotoxicosis (a thyroid disorder), heart problems, diabetes, anaemia, osteoporosis, pituitary gland problems, liver or kidney problems. Inform your doctor if you have recently received radiation therapy with iodine. Consult your doctor before taking Thyroxine+pyridoxine+nicotinamide if you are pregnant. Thyroxine+pyridoxine+nicotinamide should be given to children only if prescribed by a doctor.

Drug Interactions

Drug-Drug Interactions: Thyroxine+pyridoxine+nicotinamide may interact with antihypertensive (metoprolol), antacid (esomeprazole), supplements (calcium, vitamin D), anti-convulsant (phenytoin, phenobarbital), anti-Parkinson (levodopa), anti-neoplastic agent (altretamine).

Drug-Food Interactions: Avoid consumption of foods such as soybean flour, cottonseed meal, dietary fibre, walnuts, calcium, and calcium-fortified juices along with Thyroxine+pyridoxine+nicotinamide.

Drug-Disease Interactions: Inform your doctor if you have epilepsy, adrenal gland disorder, thyrotoxicosis (a thyroid disorder), heart problems, diabetes, anaemia, osteoporosis, or pituitary gland problems.

Drug-Drug Interactions Checker List:

  • METOPROLOL
  • ESOMEPRAZOLE
  • PHENYTOIN
  • PHENOBARBITAL
  • VITAMIN D
  • CALCIUM
  • LEVODOPA
  • ALTRETAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is unknown if alcohol interacts with Thyroxine+pyridoxine+nicotinamide. Please consult your doctor.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant or if you have any concerns regarding this. Your doctor will decide whether pregnant women can take Thyroxine+pyridoxine+nicotinamide or not.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      Thyroxine+pyridoxine+nicotinamide is safe to be taken by breastfeeding mothers if prescribed by the doctor.

    • Safety Warning

      Driving

      safe if prescribed

      Thyroxine+pyridoxine+nicotinamide generally does not affect your ability to drive. However, drive or handle machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Thyroxine+pyridoxine+nicotinamide should be used in children only if prescribed by the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eating the right nutrients and taking a regular dose of your prescribed medications may help reduce your symptoms and improve your thyroid function. 
    • People with hypothyroidism usually have a slower metabolism. Eating more protein may help boost their metabolism.
    • Yoga and aerobic exercises can help in boosting metabolism.
    • People with hypothyroidism should prefer the intake of more vegetables, fruits and lean meats. These foods are low in calories and may help prevent weight gain.
    • Avoid taking Goitrogens (agents which interfere with the normal function of the thyroid gland) which generally include soy foods (tofu), cabbage, broccoli, kale, cauliflower, spinach, sweet potatoes, cassava, peaches, strawberries, millet, pine nuts, peanuts, etc.

    Special Advise

    • Your doctor may advise regular thyroid function tests (T3, T4 and TSH) while taking Thyroxine+pyridoxine+nicotinamide. 

    Patients Concern

    Disease/Condition Glossary

    Hypothyroidism: It is a chronic condition in which the thyroid gland is unable to produce enough thyroid hormone to fulfil the needs of the body. The thyroid gland is a small gland that is located at the front of the neck and is responsible for releasing hormones (tri-iodothyronine (T3) and thyroxine (T4)) which are required for the proper functioning of the body. Without enough amount of thyroid hormone, the body's metabolism slows down, and a person feels less energetic. Early symptoms of hypothyroidism are fatigue and weight gain. Other symptoms include fatigue, weight gain, depression, constipation, feeling cold, decreased sweating, slowed heart rate, elevated blood cholesterol, dry skin, thinning hair, impaired memory, menstrual changes, muscle weakness, muscle stiffness and hoarseness. 

    FAQs

    Thyroxine+pyridoxine+nicotinamide is a combination of three drugs, namely: Thyroxine, Pyridoxine and Nicotinamide. Thyroxine is a synthetic thyroid hormone that is chemically similar to thyroxine produced by the thyroid gland. It replaces the thyroid hormone that the thyroid gland is unable to produce. Pyridoxine and Nicotinamide help in providing essential nutrients. Together, Thyroxine+pyridoxine+nicotinamide helps in treating hypothyroidism.

    Do not stop taking Thyroxine+pyridoxine+nicotinamide on your own as it may cause an imbalance in the body leading to very serious conditions affecting your metabolism. To treat your condition effectually, continue taking Thyroxine+pyridoxine+nicotinamide for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty whilst taking Thyroxine+pyridoxine+nicotinamide.

    A thyroid profile test is suggested by the doctor to check if Thyroxine+pyridoxine+nicotinamide is working effectively. You will observe a decrease in your TSH level after regular intake of Thyroxine+pyridoxine+nicotinamide as prescribed by your doctor.

    No, Thyroxine+pyridoxine+nicotinamide does not help in treating obesity or weight problems. Thyroxine+pyridoxine+nicotinamide is intended to treat underactive thyroid/hypothyroidism only.

    Consult your doctor before taking any weight-loss medicines or appetite suppressants along with Thyroxine+pyridoxine+nicotinamide as it might cause very unpleasant side-effects.

    Inform your doctor before taking Thyroxine+pyridoxine+nicotinamide along with anti-diabetic medicines. Dose adjustment may be needed in diabetic patients when you start treatment with Thyroxine+pyridoxine+nicotinamide. Regularly monitor blood glucose levels while taking Thyroxine+pyridoxine+nicotinamide.

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    Thyroxine+pyridoxine+nicotinamide

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